Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Moriz A. Habigt"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract To elucidate the adaptation of the right ventricle to acute and intermittently sustained afterload elevation, targeted preload reductions and afterload increases were implemented in a porcine model involving 12 pigs. Preload reduction was ac
Externí odkaz:
https://doaj.org/article/5f0426201585458d90462c3d837e75c8
Autor:
Mare Mechelinck, Marc Hein, Carolin Kupp, Till Braunschweig, Marius J. Helmedag, Axel Klinkenberg, Moriz A. Habigt, Uwe Klinge, René H. Tolba, Moritz Uhlig
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11351 (2023)
The effect of liver cirrhosis on vascular remodeling in vivo remains unknown. Therefore, this study investigates the influence of cholestatic liver cirrhosis on carotid arterial remodeling. A total of 79 male Sprague Dawley rats underwent bile duct l
Externí odkaz:
https://doaj.org/article/54d4c16903f44593bb46bfb9f6abff4b
Autor:
Moritz Uhlig, Marc Hein, Moriz A. Habigt, René H. Tolba, Till Braunschweig, Marius J. Helmedag, Melissa Arici, Alexander Theißen, Axel Klinkenberg, Uwe Klinge, Mare Mechelinck
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8147 (2023)
Cirrhotic patients often suffer from cirrhotic cardiomyopathy (CCM). Previous animal models of CCM were inconsistent concerning the time and mechanism of injury; thus, the temporal dynamics and cardiac vulnerability were studied in more detail. Rats
Externí odkaz:
https://doaj.org/article/24d15545a60a4ebbb31771ee8f4e75fa
Autor:
Moriz A. Habigt, Michelle Krieger, Jonas Gesenhues, Maike Ketelhut, Mare Mechelinck, Marc Hein
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The linearity and load insensitivity of the end-systolic pressure–volume-relationship (ESPVR), a parameter that describes the ventricular contractile state, are controversial. We hypothesize that linearity is influenced by a variable overl
Externí odkaz:
https://doaj.org/article/3ea685f54c7a43e48ff2fc7794d120d5
Publikováno v:
Mathematical and Computational Applications, Vol 27, Iss 2, p 28 (2022)
Many computer simulation models of the cardiovascular system, of varying complexity and objectives, have been proposed in physiological science. Every model needs to be parameterized and evaluated individually. We conducted a porcine animal model to
Externí odkaz:
https://doaj.org/article/717e69e59fa14a25a315a134a220dcd1
Publikováno v:
ASAIO Journal. 69:86-95
The physical fitness of patients with terminal heart failure and an implanted left ventricular assist device (LVAD) might be improved by load-adaptive control of the LVAD. In this study, three control strategies for LVAD were compared in eight pigs:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51a0a01f63f65c683187170a37073bd
https://doi.org/10.1097/mat.0000000000001722
https://doi.org/10.1097/mat.0000000000001722
Autor:
Johanne C Krueger, Moriz A Habigt, Marius J Helmedag, Moritz Uhlig, Michaela Moss, André Bleich, René H Tolba, Rolf Rossaint, Marc Hein, Mare Mechelinck
Publikováno v:
Animal Welfare. 32
Severity assessment in animals is an ongoing field of research. In particular, the question of objectifiable and meaningful parameters of score-sheets, as well as their best combination, arise. This retrospective analysis investigates the suitability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::479359dff5cf473d084fe9317e002bab
https://doi.org/10.1017/awf.2023.21
https://doi.org/10.1017/awf.2023.21
Autor:
Sebastian Billig, Marc Hein, Celine Kirchner, David Schumacher, Moriz Aljoscha Habigt, Mare Mechelinck, Dieter Fuchs, Uwe Klinge, Alexander Theißen, Christian Beckers, Christian Bleilevens, Rafael Kramann, Moritz Uhlig
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 876 (2024)
Background: Previous studies have shown cardiac abnormalities in acute liver injury, suggesting a potential role in the associated high mortality. Methods: We designed an experimental study exploring the short-term effects of acute cholestasis-induce
Externí odkaz:
https://doaj.org/article/fca834b394cb4b9f8df1b39aafc30183
Autor:
Moritz Uhlig, Marc Hein, Moriz A Habigt, René H Tolba, Till Braunschweig, Marius J Helmedag, Uwe Klinge, Alexander Koch, Christian Trautwein, Mare Mechelinck
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256790 (2021)
To investigate whether acute liver failure (ALF) leads to secondary acute myocardial injury, 100 ALF patients that were retrospectively identified in a single center based on ICD 10 codes and 8 rats from an experimental study that died early after bi
Externí odkaz:
https://doaj.org/article/d8b8f4270f9c41118c876f97a5fe48bf
Autor:
Mare Mechelinck, Carolin Kupp, Johanne C Krüger, Moriz A Habigt, Marius J Helmedag, René H Tolba, Rolf Rossaint, Marc Hein
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226430 (2019)
OBJECTIVE:A simple but reliable and safe anaesthetic procedure is required for surgical interventions in small rodents. Combined ketamine and xylazine injections are often used in rats for less invasive surgery, possibly with spontaneous breathing an
Externí odkaz:
https://doaj.org/article/1327994cc4504c359bcaba5d31a84b21