Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Moritz Wachsmuth-Melm"'
Autor:
Liv Zimmermann, Xiaohan Zhao, Jana Makroczyova, Moritz Wachsmuth-Melm, Vibhu Prasad, Zach Hensel, Ralf Bartenschlager, Petr Chlanda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Coronavirus replication is associated with the remodeling of cellular membranes, resulting in the formation of double-membrane vesicles (DMVs). A DMV-spanning pore was identified as a putative portal for viral RNA. However, the exact compone
Externí odkaz:
https://doaj.org/article/ec898bd6b18840459e8a9139b107c87a
Autor:
Steffen Klein, Mirko Cortese, Sophie L. Winter, Moritz Wachsmuth-Melm, Christopher J. Neufeldt, Berati Cerikan, Megan L. Stanifer, Steeve Boulant, Ralf Bartenschlager, Petr Chlanda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Here the authors visualize SARS-CoV-2 infected cells by in situ cryo-electron tomography, delineating the structural organization and conformational changes that occur during virus replication and budding; and provide insight into vRNP architecture a
Externí odkaz:
https://doaj.org/article/7a032aa67d8d4439ad792070dcdf9862
Autor:
Liv Zimmermann, Xiaohan Zhao, Jana Makroczyova, Moritz Wachsmuth-Melm, Vibhu Prasad, Ralf Bartenschlager, Petr Chlanda
Coronavirus replication is associated with the remodeling of cellular membranes resulting in the formation of double-membrane vesicles (DMVs). Recently, a pore spanning DMV was identified as a putative portal for viral RNA transcription and replicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7590abd4eed6721c7375e85f9d66a452
https://doi.org/10.1101/2022.10.21.513196
https://doi.org/10.1101/2022.10.21.513196
Autor:
Steffen Klein, Gonen Golani, Fabio Lolicato, Carmen Lahr, Daniel Beyer, Alexia Herrmann, Moritz Wachsmuth-Melm, Nina Reddmann, Romy Brecht, Mehdi Hosseinzadeh, Androniki Kolovou, Jana Makroczyova, Sarah Peterl, Martin Schorb, Yannick Schwab, Britta Brügger, Walter Nickel, Ulrich S. Schwarz, Petr Chlanda
Interferon-induced transmembrane protein 3 (IFITM3) inhibits the entry of numerous viruses through undefined molecular mechanisms. IFITM3 localizes in the endosomal-lysosomal system and specifically impacts virus fusion with target cell membranes. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0653c4d3a678dfa01922575f8a2b56
https://doi.org/10.1101/2022.09.01.506185
https://doi.org/10.1101/2022.09.01.506185
Autor:
Megan L. Stanifer, Steeve Boulant, Steffen Klein, Sophie L. Winter, Christopher J. Neufeldt, Berati Cerikan, Petr Chlanda, Moritz Wachsmuth-Melm, Mirko Cortese, Ralf Bartenschlager
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID19 pandemic, is a highly pathogenic β-coronavirus. As other coronaviruses, SARS-CoV-2 is enveloped, replicates in the cytoplasm and assembles at intracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e622d1d943c776afd9a185ec7d0626
https://doaj.org/article/7a032aa67d8d4439ad792070dcdf9862
https://doaj.org/article/7a032aa67d8d4439ad792070dcdf9862
Publikováno v:
Methods in cell biology. 162
In situ cryo-electron tomography of cryo-focused ion beam (cryo-FIB) milled cells enables the study of cellular organelles in unperturbed conditions and close to the molecular resolution. However, due to the crowdedness of the cellular environment, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0ac866aa551120dc3a8b3cdb53092f0
https://pubmed.ncbi.nlm.nih.gov/33707016
https://pubmed.ncbi.nlm.nih.gov/33707016
Publikováno v:
Methods in Cell Biology ISBN: 9780128220580
In situ cryo-electron tomography of cryo-focused ion beam (cryo-FIB) milled cells enables the study of cellular organelles in unperturbed conditions and close to the molecular resolution. However, due to the crowdedness of the cellular environment, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b2f25b33f7613a0a257f563c7a00f65
https://doi.org/10.1016/bs.mcb.2020.12.009
https://doi.org/10.1016/bs.mcb.2020.12.009
Autor:
Steeve Boulant, Mirko Cortese, Petr Chlanda, Megan L. Stanifer, Sophie L. Winter, Berati Cerikan, Steffen Klein, Christopher J. Neufeldt, Ralf Bartenschlager, Moritz Wachsmuth-Melm
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID19 pandemic, is a highly pathogenic β-coronavirus. As other coronaviruses, SARS-CoV-2 is enveloped, replicates in the cytoplasm and assembles at intracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a544e8daea6db00f4e6510bdfc52c91
https://doi.org/10.1101/2020.06.23.167064
https://doi.org/10.1101/2020.06.23.167064