Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Moritz Kochanek"'
Autor:
Gero Knittel, Hans Christian Reinhardt, Ari M. Melnick, Ron D. Jachimowicz, Bastian von Tresckow, F. Thomas Wunderlich, Branko Zevnik, Bjoern Chapuy, Joachim R. Göthert, Sebastian Klein, Markus Chmielewski, Dinis Pedro Calado, Michael Hallek, Thorsten Persigehl, Monika Ortmann, Jörn Meinel, Philipp Lohneis, Reinhard Büttner, Alessandra Holzem, Filippo Beleggia, Lorenz Jonigkeit, Jacqueline Knüfer, Moritz Kochanek, Roman K. Thomas, Graziella Bosco, Nima Abedpour, Martin Peifer, Phuong-Hien Nguyen, Viktoria Kohlhas, Tobias Riet, Ilmars Kisis, Tim Lohmann, Pascal Nieper, Benedikt W. Pelzer, Julia Hansen, Ruth Flümann
Table S1 contains the p values of comparisons of the V gene usage in non-malignant GC B cells between the individual genotypes. These comparisons were done on the family, gene and allele level. V usage was compared for all BCR sequences as well as fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16522456824017cbee9d61e5a078d618
https://doi.org/10.1158/2643-3230.22546170.v1
https://doi.org/10.1158/2643-3230.22546170.v1
Autor:
Gero Knittel, Hans Christian Reinhardt, Ari M. Melnick, Ron D. Jachimowicz, Bastian von Tresckow, F. Thomas Wunderlich, Branko Zevnik, Bjoern Chapuy, Joachim R. Göthert, Sebastian Klein, Markus Chmielewski, Dinis Pedro Calado, Michael Hallek, Thorsten Persigehl, Monika Ortmann, Jörn Meinel, Philipp Lohneis, Reinhard Büttner, Alessandra Holzem, Filippo Beleggia, Lorenz Jonigkeit, Jacqueline Knüfer, Moritz Kochanek, Roman K. Thomas, Graziella Bosco, Nima Abedpour, Martin Peifer, Phuong-Hien Nguyen, Viktoria Kohlhas, Tobias Riet, Ilmars Kisis, Tim Lohmann, Pascal Nieper, Benedikt W. Pelzer, Julia Hansen, Ruth Flümann
Table S4 contains the individual mutations of PPMBC and MBC lymphomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7ee124fadfef4d6723c99c569ec724
https://doi.org/10.1158/2643-3230.22546161.v1
https://doi.org/10.1158/2643-3230.22546161.v1
Autor:
Gero Knittel, Hans Christian Reinhardt, Ari M. Melnick, Ron D. Jachimowicz, Bastian von Tresckow, F. Thomas Wunderlich, Branko Zevnik, Bjoern Chapuy, Joachim R. Göthert, Sebastian Klein, Markus Chmielewski, Dinis Pedro Calado, Michael Hallek, Thorsten Persigehl, Monika Ortmann, Jörn Meinel, Philipp Lohneis, Reinhard Büttner, Alessandra Holzem, Filippo Beleggia, Lorenz Jonigkeit, Jacqueline Knüfer, Moritz Kochanek, Roman K. Thomas, Graziella Bosco, Nima Abedpour, Martin Peifer, Phuong-Hien Nguyen, Viktoria Kohlhas, Tobias Riet, Ilmars Kisis, Tim Lohmann, Pascal Nieper, Benedikt W. Pelzer, Julia Hansen, Ruth Flümann
Table S6 contains clinical parameters and sequencing results of human DLBCL samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6782abe7230ecc2ba43e0aca7aecb86b
https://doi.org/10.1158/2643-3230.22546152.v1
https://doi.org/10.1158/2643-3230.22546152.v1
Autor:
Gero Knittel, Hans Christian Reinhardt, Clemens A. Schmitt, Martin Peifer, Thorsten Persigehl, Anthony Letai, Arndt Borkhardt, Hamid Kashkar, Reinhard Büttner, Philipp Lohneis, Anna Brunn, Manuel Montesinos-Rongen, Sandrine Sander, Ari M. Melnick, Wendy Béguelin, Laura Pasqualucci, Lukas P. Frenzel, Andreas R. Klatt, Janine Altmüller, Martina Deckert, Marcus Krüger, Janica Wiederstein, Arina Riabinska, Maurice Reimann, Jeremy A. Ryan, Alexandra da Palma Guerreiro, Julia Hauer, Heinz Ahlert, Benedikt W. Pelzer, Ilmars Kisis, Moritz Kochanek, Sanil Bhatia, Sebastian Klein, Alessandra Holzem, Pauline Pfeiffer, Pascal Nieper, Tim Rehkämper, Ruth Flümann
Pharmacological Screen IC50 values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b24c0c678d7d5feb1dbbae1529f6df7
https://doi.org/10.1158/2643-3230.22542673
https://doi.org/10.1158/2643-3230.22542673
Autor:
Gero Knittel, Hans Christian Reinhardt, Ari M. Melnick, Ron D. Jachimowicz, Bastian von Tresckow, F. Thomas Wunderlich, Branko Zevnik, Bjoern Chapuy, Joachim R. Göthert, Sebastian Klein, Markus Chmielewski, Dinis Pedro Calado, Michael Hallek, Thorsten Persigehl, Monika Ortmann, Jörn Meinel, Philipp Lohneis, Reinhard Büttner, Alessandra Holzem, Filippo Beleggia, Lorenz Jonigkeit, Jacqueline Knüfer, Moritz Kochanek, Roman K. Thomas, Graziella Bosco, Nima Abedpour, Martin Peifer, Phuong-Hien Nguyen, Viktoria Kohlhas, Tobias Riet, Ilmars Kisis, Tim Lohmann, Pascal Nieper, Benedikt W. Pelzer, Julia Hansen, Ruth Flümann
This file contains the Supplementary Figures S1 to S12.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cef089d690f63351b9669b9955cf0e
https://doi.org/10.1158/2643-3230.22546173
https://doi.org/10.1158/2643-3230.22546173
Autor:
Gero Knittel, Hans Christian Reinhardt, Ari M. Melnick, Ron D. Jachimowicz, Bastian von Tresckow, F. Thomas Wunderlich, Branko Zevnik, Bjoern Chapuy, Joachim R. Göthert, Sebastian Klein, Markus Chmielewski, Dinis Pedro Calado, Michael Hallek, Thorsten Persigehl, Monika Ortmann, Jörn Meinel, Philipp Lohneis, Reinhard Büttner, Alessandra Holzem, Filippo Beleggia, Lorenz Jonigkeit, Jacqueline Knüfer, Moritz Kochanek, Roman K. Thomas, Graziella Bosco, Nima Abedpour, Martin Peifer, Phuong-Hien Nguyen, Viktoria Kohlhas, Tobias Riet, Ilmars Kisis, Tim Lohmann, Pascal Nieper, Benedikt W. Pelzer, Julia Hansen, Ruth Flümann
Table S3 contains B cell receptor repertoire sequencing data and lists the individual sublcones of the dominant clones of MBC, SMBC and PPMBC lymphomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11864e0a3b5a9be31da35506c7cd1e9d
https://doi.org/10.1158/2643-3230.22546164.v1
https://doi.org/10.1158/2643-3230.22546164.v1
Autor:
Gero Knittel, Hans Christian Reinhardt, Clemens A. Schmitt, Martin Peifer, Thorsten Persigehl, Anthony Letai, Arndt Borkhardt, Hamid Kashkar, Reinhard Büttner, Philipp Lohneis, Anna Brunn, Manuel Montesinos-Rongen, Sandrine Sander, Ari M. Melnick, Wendy Béguelin, Laura Pasqualucci, Lukas P. Frenzel, Andreas R. Klatt, Janine Altmüller, Martina Deckert, Marcus Krüger, Janica Wiederstein, Arina Riabinska, Maurice Reimann, Jeremy A. Ryan, Alexandra da Palma Guerreiro, Julia Hauer, Heinz Ahlert, Benedikt W. Pelzer, Ilmars Kisis, Moritz Kochanek, Sanil Bhatia, Sebastian Klein, Alessandra Holzem, Pauline Pfeiffer, Pascal Nieper, Tim Rehkämper, Ruth Flümann
WES Mutations Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10dee7df83b0531e2b2b3318be35c1df
https://doi.org/10.1158/2643-3230.22542676
https://doi.org/10.1158/2643-3230.22542676
Autor:
Gero Knittel, Hans Christian Reinhardt, Clemens A. Schmitt, Martin Peifer, Thorsten Persigehl, Anthony Letai, Arndt Borkhardt, Hamid Kashkar, Reinhard Büttner, Philipp Lohneis, Anna Brunn, Manuel Montesinos-Rongen, Sandrine Sander, Ari M. Melnick, Wendy Béguelin, Laura Pasqualucci, Lukas P. Frenzel, Andreas R. Klatt, Janine Altmüller, Martina Deckert, Marcus Krüger, Janica Wiederstein, Arina Riabinska, Maurice Reimann, Jeremy A. Ryan, Alexandra da Palma Guerreiro, Julia Hauer, Heinz Ahlert, Benedikt W. Pelzer, Ilmars Kisis, Moritz Kochanek, Sanil Bhatia, Sebastian Klein, Alessandra Holzem, Pauline Pfeiffer, Pascal Nieper, Tim Rehkämper, Ruth Flümann
Based on gene expression profiles, diffuse large B-cell lymphoma (DLBCL) is subdivided into germinal center B-cell–like (GCB) and activated B-cell–like (ABC) DLBCL. Two of the most common genomic aberrations in ABC-DLBCL are mutations in MYD88 as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be2bb69b8adfd9f6af9c3c822eed536
https://doi.org/10.1158/2643-3230.c.6550018
https://doi.org/10.1158/2643-3230.c.6550018
Autor:
Gero Knittel, Hans Christian Reinhardt, Ari M. Melnick, Ron D. Jachimowicz, Bastian von Tresckow, F. Thomas Wunderlich, Branko Zevnik, Bjoern Chapuy, Joachim R. Göthert, Sebastian Klein, Markus Chmielewski, Dinis Pedro Calado, Michael Hallek, Thorsten Persigehl, Monika Ortmann, Jörn Meinel, Philipp Lohneis, Reinhard Büttner, Alessandra Holzem, Filippo Beleggia, Lorenz Jonigkeit, Jacqueline Knüfer, Moritz Kochanek, Roman K. Thomas, Graziella Bosco, Nima Abedpour, Martin Peifer, Phuong-Hien Nguyen, Viktoria Kohlhas, Tobias Riet, Ilmars Kisis, Tim Lohmann, Pascal Nieper, Benedikt W. Pelzer, Julia Hansen, Ruth Flümann
Genomic profiling revealed the identity of at least 5 subtypes of diffuse large B-cell lymphoma (DLBCL), including the MCD/C5 cluster characterized by aberrations in MYD88, BCL2, PRDM1, and/or SPIB. We generated mouse models harboring B cell–specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278e9a4312ef1b4ce85aa06afa865ce1
https://doi.org/10.1158/2643-3230.c.6551112.v1
https://doi.org/10.1158/2643-3230.c.6551112.v1
Autor:
Gero Knittel, Hans Christian Reinhardt, Clemens A. Schmitt, Martin Peifer, Thorsten Persigehl, Anthony Letai, Arndt Borkhardt, Hamid Kashkar, Reinhard Büttner, Philipp Lohneis, Anna Brunn, Manuel Montesinos-Rongen, Sandrine Sander, Ari M. Melnick, Wendy Béguelin, Laura Pasqualucci, Lukas P. Frenzel, Andreas R. Klatt, Janine Altmüller, Martina Deckert, Marcus Krüger, Janica Wiederstein, Arina Riabinska, Maurice Reimann, Jeremy A. Ryan, Alexandra da Palma Guerreiro, Julia Hauer, Heinz Ahlert, Benedikt W. Pelzer, Ilmars Kisis, Moritz Kochanek, Sanil Bhatia, Sebastian Klein, Alessandra Holzem, Pauline Pfeiffer, Pascal Nieper, Tim Rehkämper, Ruth Flümann
BCR sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea72be7b54ae6be765d5f479d8252f1
https://doi.org/10.1158/2643-3230.22542670.v1
https://doi.org/10.1158/2643-3230.22542670.v1