Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Moritz Jesinghaus"'
Autor:
Max B. Albers, Martina Sevcik, Dominik Wiese, Jerena Manoharan, Anja Rinke, Moritz Jesinghaus, Detlef K. Bartsch
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Functioning pancreatic neuroendocrine neoplasms other than insulinomas and gastrinomas (rf-pNENs) are exceptionally rare tumours. Thus, their characteristics and long-term prognosis have not been well defined. This article aims to present da
Externí odkaz:
https://doaj.org/article/cdc97dfde5004dd783adf949c2640373
Autor:
Sebastian Foersch, Maxime Schmitt, Anne‐Sophie Litmeyer, Markus Tschurtschenthaler, Thomas Gress, Detlef K Bartsch, Nicole Pfarr, Katja Steiger, Carsten Denkert, Moritz Jesinghaus
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 5, Pp n/a-n/a (2024)
Abstract Antibody–drug conjugates (ADCs) directed to trophoblast cell surface antigen 2 (TROP2) have gained approval as a therapeutic option for advanced triple‐negative breast cancer, and TROP2 expression has been linked to unfavourable outcomes
Externí odkaz:
https://doaj.org/article/8a36804c34c64ace9a0a2bc6238a569b
Autor:
Anne‐Sophie Litmeyer, Björn Konukiewitz, Atsuko Kasajima, Sebastian Foersch, Felix Schicktanz, Maxime Schmitt, Franziska Kellers, Albert Grass, Paul Jank, Bettina Lehman, Thomas M Gress, Anja Rinke, Detlef K Bartsch, Carsten Denkert, Wilko Weichert, Günter Klöppel, Moritz Jesinghaus
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 6, Pp 498-509 (2023)
Abstract Complementary to synaptophysin and chromogranin A, insulinoma‐associated protein 1 (INSM1) has emerged as a sensitive marker for the diagnosis of neuroendocrine neoplasms. Since there are no comparative data regarding INSM1 expression in c
Externí odkaz:
https://doaj.org/article/341b6cb122f243fc92b1c5ab08d08acc
Autor:
Paul Jank, Jonas Leichsenring, Svenja Kolb, Inga Hoffmann, Philip Bischoff, Catarina Alisa Kunze, Mihnea P. Dragomir, Moritz Gleitsmann, Moritz Jesinghaus, Wolfgang D. Schmitt, Hagen Kulbe, Christine Sers, Albrecht Stenzinger, Jalid Sehouli, Ioana Elena Braicu, Christina Westhoff, David Horst, Carsten Denkert, Stefan Gröschel, Eliane T. Taube
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background Mechanisms of development and progression of high-grade serous ovarian cancer (HGSOC) are poorly understood. EVI1 and PARP1, part of TGF-ß pathway, are upregulated in cancers with DNA repair deficiencies with DNA repair deficienc
Externí odkaz:
https://doaj.org/article/6475539f264d451aaaf6ee746f0741b3
Autor:
Mariel C. Paul, Christian Schneeweis, Chiara Falcomatà, Chuan Shan, Daniel Rossmeisl, Stella Koutsouli, Christine Klement, Magdalena Zukowska, Sebastian A. Widholz, Moritz Jesinghaus, Konstanze K. Heuermann, Thomas Engleitner, Barbara Seidler, Katia Sleiman, Katja Steiger, Markus Tschurtschenthaler, Benjamin Walter, Sören A. Weidemann, Regina Pietsch, Angelika Schnieke, Roland M. Schmid, Maria S. Robles, Geoffroy Andrieux, Melanie Boerries, Roland Rad, Günter Schneider, Dieter Saur
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
SNAIL promotes tumour metastasis through inducing epithelial to mesenchymal transition (EMT). Here the authors report that SNAIL bypasses senescence and regulates cell cycle progression to promote pancreatic carcinogenesis and this is independent of
Externí odkaz:
https://doaj.org/article/fdf4c0ab459c4aa5ae822ae980ab27e7
Autor:
Moritz Jesinghaus, Melanie Boxberg, Maxime Schmitt, Mark Kriegsmann, Alexander Harms, Corinna Lang, Thomas Muley, Hauke Winter, Katharina Kriegsmann, Arne Warth, Albrecht Stenzinger, Carsten Denkert, Hans Hoffmann, Seyer Safi, Wilko Weichert
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 6, Pp 567-578 (2022)
Abstract Grading of squamous cell carcinomas (SCCs) based on tumour budding and cell nest size has been termed cellular dissociation grading (CDG) and was suggested as a robust outcome predictor when assessed in biopsies and resections of various ext
Externí odkaz:
https://doaj.org/article/fc3c4b257ebd4b42b7c5c1c7e231e8a1
Autor:
Moritz Jesinghaus, Anna‐Lina Herz, Meike Kohlruss, Miguel Silva, Albert Grass, Sebastian Lange, Alexander Novotny, Katja Ott, Thomas Schmidt, Matthias Gaida, Alexander Hapfelmeier, Carsten Denkert, Wilko Weichert, Gisela Keller
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 5, Pp 448-457 (2022)
Abstract Tumour budding (TB) has been associated with adverse clinicopathological factors and poor survival in a plethora of therapy‐naïve carcinoma entities including gastric adenocarcinoma (GC). As conventional histopathological grading is usual
Externí odkaz:
https://doaj.org/article/92ec24fc6db94372ab41267445c0bb90
Autor:
Lisa Marr, Bernhard Haller, Thomas Pyka, Jan C. Peeken, Moritz Jesinghaus, Klemens Scheidhauer, Helmut Friess, Stephanie E. Combs, Stefan Münch
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Aim of this study was to validate the prognostic impact of clinical parameters and baseline 18F-FDG-PET/CT derived textural features to predict histopathologic response and survival in patients with esophageal squamous cell carcinoma undergo
Externí odkaz:
https://doaj.org/article/e8829ab2129543d08789672eb5437be5
Autor:
Anna‐Lina Herz, Sarah Wisser, Meike Kohlruss, Julia Slotta‐Huspenina, Moritz Jesinghaus, Bianca Grosser, Katja Steiger, Alexander Novotny, Alexander Hapfelmeier, Thomas Schmidt, Matthias M Gaida, Wilko Weichert, Gisela Keller
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 3, Pp 233-244 (2022)
Abstract We investigated the clinical impact of elevated microsatellite instability at selected tetranucleotide (EMAST) repeats in the context of neoadjuvant chemotherapy (CTx) in gastric/gastro‐oesophageal adenocarcinomas. We analysed 583 resected
Externí odkaz:
https://doaj.org/article/e5e6877fff83436aa6d11d902a591f00
Autor:
David Schult, Sandra Reitmeier, Plamena Koyumdzhieva, Tobias Lahmer, Moritz Middelhoff, Johanna Erber, Jochen Schneider, Juliane Kager, Marina Frolova, Julia Horstmann, Lisa Fricke, Katja Steiger, Moritz Jesinghaus, Klaus-Peter Janssen, Ulrike Protzer, Klaus Neuhaus, Roland M. Schmid, Dirk Haller, Michael Quante
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
There is a growing debate about the involvement of the gut microbiome in COVID-19, although it is not conclusively understood whether the microbiome has an impact on COVID-19, or vice versa, especially as analysis of amplicon data in hospitalized pat
Externí odkaz:
https://doaj.org/article/0d64f28858eb4fdba2a6630ef6f2d6ee