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pro vyhledávání: '"Moritz A. Kirchner"'
Autor:
Coline Plé, Heng-Keat Tam, Anais Vieira Da Cruz, Nina Compagne, Juan-Carlos Jiménez-Castellanos, Reinke T. Müller, Elizabeth Pradel, Wuen Ee Foong, Giuliano Malloci, Alexia Ballée, Moritz A. Kirchner, Parisa Moshfegh, Adrien Herledan, Andrea Herrmann, Benoit Deprez, Nicolas Willand, Attilio Vittorio Vargiu, Klaas M. Pos, Marion Flipo, Ruben C. Hartkoorn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Efflux transporters of the RND family confer resistance to multiple antibiotics in Gram-negative bacteria. Here, the authors identify pyridylpiperazine-based compounds that potentiate antibiotic activity in E. coli through allosteric inhibition of it
Externí odkaz:
https://doaj.org/article/2d5e83c99b5c4265bf969d47fed84ba5