Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Moritz, Radbruch"'
Autor:
Pedro Osorio, Guillermo Jimenez-Perez, Javier Montalt-Tordera, Jens Hooge, Guillem Duran-Ballester, Shivam Singh, Moritz Radbruch, Ute Bach, Sabrina Schroeder, Krystyna Siudak, Julia Vienenkoetter, Bettina Lawrenz, Sadegh Mohammadi
Publikováno v:
Diagnostics, Vol 14, Iss 13, p 1442 (2024)
Artificial Intelligence (AI)-based image analysis has immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially powerful solu
Externí odkaz:
https://doaj.org/article/54e91f0a90cb42fda1e3c97fecbca72b
Autor:
Moritz Radbruch, Hannah Pischon, Fang Du, Rainer Haag, Fabian Schumacher, Burkhard Kleuser, Lars Mundhenk, Achim D. Gruber
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 349
Two challenges in topical drug delivery to the skin include solubilizing hydrophobic drugs in water-based formulations and increasing drug penetration into the skin. Polymeric core-multishell nanocarrier (CMS), particularly the novel biodegradable CM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8e3aa2d8d6021ba3aad10c130c96c1
https://pubmed.ncbi.nlm.nih.gov/35905785
https://pubmed.ncbi.nlm.nih.gov/35905785
Autor:
Moritz Radbruch, Jörg Raabe, Annika Vogt, Lars Mundhenk, Sebastian Bachmann, Achim D. Gruber, Fiorenza Rancan, Eckart Rühl, R. Gurny, Benjamin Watts, A. Klossek, Hannah Pischon, K. Yamamoto, R. Flesch, Petra Schrade, Ulrike Blume-Peytavi, K. Fuchs
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 139:68-75
The penetration of topically applied tacrolimus formulated in micelles into murine skin is reported, measured by X-ray microscopy. Tacrolimus and micelles are probed for the first time by this high spatial resolution technique by element-selective ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268c2f8274db8b7b4c2043f70bc2cb30
https://doi.org/10.1016/j.ejpb.2019.03.006
https://doi.org/10.1016/j.ejpb.2019.03.006
Autor:
Moritz Radbruch, Stefan Hönzke, Sarah Hedtrich, Leonie Wallmeyer, Monika Schäfer-Korting, Anja Ostrowski, Lars Mundhenk
Publikováno v:
Journal of Investigative Dermatology. 136(3):631-639
Atopic dermatitis is a chronic skin condition with complex etiology. It is characterized by skin barrier defects and T helper type 2 (Th2)-polarized inflammation. Although mutations in the filaggrin gene are known to be prominent genetic risk factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b6b9c30d38f702373a2df5f85a054e
Autor:
Lars Mundhenk, Moritz Radbruch, Jens Balke, Falko Neumann, Nan Ma, Robert Brodwolf, Alexander Wolf, Hannah Pischon, Achim D. Gruber, Ulrike Alexiev, Pierre Volz
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 14(23)
Nanoparticles hold a great promise in biomedical science. However, due to their unique physical and chemical properties they can lead to overproduction of intracellular reactive oxygen species (ROS). As an important mechanism of nanotoxicity, there i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b200d120d89e050246658674e029dd8c
https://pubmed.ncbi.nlm.nih.gov/29726099
https://pubmed.ncbi.nlm.nih.gov/29726099
Autor:
Anja Ostrowski, Stefan Hönzke, Moritz Radbruch, Achim D. Gruber, Hannah Pischon, Joachim W. Fluhr, Sarah Hedtrich, Lars Mundhenk, Fabian Schumacher, Burkhard Kleuser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eaf02cc94148b5e5764ab041b7a20ff
https://www.ncbi.nlm.nih.gov/pubmed/28947356
https://www.ncbi.nlm.nih.gov/pubmed/28947356
Autor:
Moritz, Radbruch, Hannah, Pischon, Anja, Ostrowski, Pierre, Volz, Robert, Brodwolf, Falko, Neumann, Michael, Unbehauen, Burkhard, Kleuser, Rainer, Haag, Nan, Ma, Ulrike, Alexiev, Lars, Mundhenk, Achim D, Gruber
Publikováno v:
Nanoscale Research Letters
Dendritic hPG-amid-C18-mPEG core-multishell nanocarriers (CMS) represent a novel class of unimolecular micelles that hold great potential as drug transporters, e.g., to facilitate topical therapy in skin diseases. Atopic dermatitis is among the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be4ca9336bc3b2a35821f329ff551030
https://pubmed.ncbi.nlm.nih.gov/28116609
https://pubmed.ncbi.nlm.nih.gov/28116609
Autor:
Lars Mundhenk, Rainer Haag, Pierre Volz, Michael Unbehauen, Ulrike Alexiev, Moritz Radbruch, Joachim W. Fluhr, Sarah Hedtrich, Stefan Hönzke, Burkhard Kleuser, Achim D. Gruber, Hannah Pischon, Christian Gerecke, Anja Ostrowski
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 13(1)
Inflammatory disorders of the skin pose particular therapeutic challenges due to complex structural and functional alterations of the skin barrier. Penetration of several anti-inflammatory drugs is particularly problematic in psoriasis, a common derm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0518163536d1c49f599397bf43c7158
https://pubmed.ncbi.nlm.nih.gov/27697619
https://pubmed.ncbi.nlm.nih.gov/27697619
Autor:
Hannah Pischon, Lars Mundhenk, Moritz Radbruch, B. Kleuser, K. Yamamoto, Rainer Haag, A. Klossek, F. Du, Eckart Rühl, F. Schumacher, Achim D. Gruber
Publikováno v:
Journal of Comparative Pathology. 166:103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c25573c0d7368b8acfa60217b912b0b3
https://doi.org/10.1016/j.jcpa.2018.10.011
https://doi.org/10.1016/j.jcpa.2018.10.011
Autor:
Hannah Pischon, Nan Ma, Jens Balke, Alexander Wolf, Pierre Volz, Lars Mundhenk, Moritz Radbruch, Ulrike Alexiev, Falko Neumann, Achim D. Gruber, Robert Brodwolf
Publikováno v:
Small. 14:1870106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4feba2e1ae3178a4c589ef2dcdb1965
https://doi.org/10.1002/smll.201870106
https://doi.org/10.1002/smll.201870106