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pro vyhledávání: '"Moritsuka, Akihiro"'
Autor:
Miyamoto, Hirotaka, Matsueda, Satoshi, Moritsuka, Akihiro, Shimokawa, Kenta, Hirata, Haruna, Nakashima, Mikiro, Sasaki, Hitoshi, Fumoto, Shintaro, Nishida, Koyo
Publikováno v:
Biopharmaceutics & Drug Disposition. 36(7):481-489
The effect of hypothermia on the in vivo pharmacokinetics of midazolam was evaluated, with a focus on altered metabolism in the liver and binding to serum proteins. Rat primary hepatocytes were incubated with midazolam (which is metabolized mainly by