Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Moritsugu Kimura"'
Autor:
Masumi Kondo, Kaichiro Sawada, Yosuke Matsuda, Makiko Abe, Noriyuki Sanechika, Yumi Takanashi, Yoshitaka Mori, Moritsugu Kimura, Masao Toyoda
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1771 (2024)
Deuterium-depleted water (DDW) is used in the treatment of many diseases, including cancer and diabetes. To detect the effect of DDW on gene expression and activation of the insulin-responsive transporter GLUT4 as a mechanism for improving the pathol
Externí odkaz:
https://doaj.org/article/3ce4f6ca52ff4bd0a39a2c6e47f45f0c
Autor:
Yoshimi Muta, Kazuo Kobayashi, Masao Toyoda, Atsuhito Tone, Daisuke Suzuki, Daisuke Tsuriya, Hideo Machimura, Hidetoshi Shimura, Hiroshi Takeda, Hisashi Yokomizo, Kei Takeshita, Keiichi Chin, Keizo Kanasaki, Kouichi Tamura, Masaaki Miyauchi, Masuo Saburi, Miwa Morita, Miwako Yomota, Moritsugu Kimura, Nobuo Hatori, Shinichi Nakajima, Shun Ito, Shunichiro Tsukamoto, Takashi Murata, Takaya Matsushita, Takayuki Furuki, Takuya Hashimoto, Tomoya Umezono, Yuichi Takashi, Daiji Kawanami
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Accumulating evidence has demonstrated that both SGLT2 inhibitors (SGLT2i) and GLP-1 receptor agonists (GLP1Ra) have protective effects in patients with diabetic kidney disease. Combination therapy with SGLT2i and GLP1Ra is commonly used in patients
Externí odkaz:
https://doaj.org/article/e387d4d5ba7242e08853f9abf1debf8d
Autor:
Yuki Ohashi, Masao Toyoda, Nobumichi Saito, Masahiro Koizumi, Genta Kanai, Hirotaka Komaba, Moritsugu Kimura, Takehiko Wada, Hiroo Takahashi, Yuichiro Takahashi, Naoto Ishida, Takatoshi Kakuta, Masafumi Fukagawa, Kimiyoshi Ichida
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Two-thirds of urate is excreted via the renal pathway and the remaining one-third via the extra-renal pathway, the latter mainly via the intestine in healthy individuals. ABCG2, a urate exporter, is expressed in various tissues including the
Externí odkaz:
https://doaj.org/article/0e483fa5cdb84734b9795fd2b63716f9
Autor:
Masao Toyoda, Nobumichi Saito, Moritsugu Kimura, Nobuo Hatori, Kouichi Tamura, Masaaki Miyakawa, Kazuyoshi Sato, Akira Kanamori, Kazuo Kobayashi
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 9, Pp 1520-1527 (2022)
ABSTRACT Aims/Introduction We previously reported that sodium–glucose cotransporter 2 inhibitor (SGLT2i) treatment was associated with an improvement of the albumin‐to‐creatinine ratio in Japanese patients with type 2 diabetes mellitus and chro
Externí odkaz:
https://doaj.org/article/9d29947443064f66a7b0e820db4c0a8b
Autor:
Jun Ito, Moritsugu Kimura, Tomoyuki Toya, Konomi Isozumi, Atsuro Kawaji, Yudai Isozaki, Masafumi Fukagawa
Publikováno v:
Renal Replacement Therapy, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Background The mortality rate of novel coronaviral disease (COVID-19) patients undergoing dialysis is considerably higher than that of patients with normal kidney function. As of August 2021, only remdesivir has been approved in Japan as an
Externí odkaz:
https://doaj.org/article/26c67d1ee856469c8358bdeb69d3ce00
Autor:
Nobumichi Saito, Masao Toyoda, Masumi Kondo, Makiko Abe, Noriyuki Sanechika, Moritsugu Kimura, Kaichiro Sawada, Masafumi Fukagawa
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 501 (2023)
(1) Background: Renal dysfunction and hypertension are mutually aggravating factors; however, the details of their interaction remain unclear. In a study using renal tissue from diabetic rats, we found that β1-integrin, a cell-substrate adhesion mol
Externí odkaz:
https://doaj.org/article/4d2d8ca123654e0eb02847a564f543e7
Autor:
Moritsugu Kimura, Masao Toyoda, Nobumichi Saito, Makiko Abe, Eri Kato, Akemi Sugihara, Naoto Ishida, Masafumi Fukagawa
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 2 (2022)
IntroductionIt is extremely important for patients with diabetes undergoing maintenance hemodialysis (MHD) to receive regular ophthalmologic examinations. However, even in the field of MHD in Japan, where there are many hemodialysis patients and the
Externí odkaz:
https://doaj.org/article/5457ecf1143c4dda9ad4dcb018fb5e60
Autor:
Kazuo Kobayashi, Masao Toyoda, Moritsugu Kimura, Nobuo Hatori, Takayuki Furuki, Hiroyuki Sakai, Masahiro Takihata, Tomoya Umezono, Shun Ito, Daisuke Suzuki, Hiroshi Takeda, Akira Kanamori, Hisakazu Degawa, Hareaki Yamamoto, Hideo Machimura, Atsuko Mokubo, Keiichi Chin, Mitsuo Obana, Toshimasa Hishiki, Kouta Aoyama, Shinichi Nakajima, Shinichi Umezawa, Hidetoshi Shimura, Togo Aoyama, Kazuyoshi Sato, Masaaki Miyakawa
Publikováno v:
Clinical and Experimental Hypertension, Vol 41, Iss 7, Pp 637-644 (2019)
Decrease in blood pressure contributes to the reno-protective effects of sodium-glucose cotransporter 2 inhibitors; however, its relationship with home monitoring of blood pressure is unclear. We retrospectively analyzed 101 visiting members of the K
Externí odkaz:
https://doaj.org/article/b1b31d2ac3f746d1be93392f3402d38a
Autor:
Moritsugu Kimura, Masao Toyoda, Nobumichi Saito, Noriko Kaneyama, Han Miyatake, Eitaro Tanaka, Hirotaka Komaba, Masanori Hara, Masafumi Fukagawa
Publikováno v:
Journal of Diabetes Research, Vol 2020 (2020)
Externí odkaz:
https://doaj.org/article/6155cbcaa82b4c9aa05c6876a4d25528
Publikováno v:
Case Reports in Medicine, Vol 2019 (2019)
The patient was a 40-year-old woman, who had been diagnosed with Prader–Willi syndrome (PWS) at 1 year of age and type 2 diabetes at 27 years of age. At 34 years of age, she was hospitalized to start insulin therapy and receive guidance on treatmen
Externí odkaz:
https://doaj.org/article/d13c67793fc14fff8198321a1d2c9c42