Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Moritoshi Hirono"'
Autor:
Moritoshi Hirono, Masanori Nakata
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Ghrelin, an orexigenic peptide ligand for growth hormone secretagogue receptor 1a (GHS-R1a), occurs not only in the stomach but also in the brain, and modulates neuronal activity and synaptic efficacy. Previous studies showed that GHS-R1a ex
Externí odkaz:
https://doaj.org/article/d1d7fd1e858e42159d21c9662d3eb017
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0286031 (2023)
γ-aminobutyric acid (GABA) is a major inhibitory neurotransmitter and its concentrations in the brain could be associated with EtOH-induced impairment of motor coordination. GABA is synthesized by two isoforms of glutamate decarboxylase (GAD): GAD65
Externí odkaz:
https://doaj.org/article/b6363bd9938a4100b84b3581451b5219
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Classically, the cerebellum has been thought to play a significant role in motor coordination. However, a growing body of evidence for novel neural connections between the cerebellum and various brain regions indicates that the cerebellum also contri
Externí odkaz:
https://doaj.org/article/2d24f72560f54b2d9ecba7c84a83db4c
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106316 (2014)
Stimulation of type I metabotropic glutamate receptors (mGluR1/5) in several neuronal types induces slow excitatory responses through activation of transient receptor potential canonical (TRPC) channels. GABAergic cerebellar molecular layer interneur
Externí odkaz:
https://doaj.org/article/47fd4b1143684a16a6dfc5db672d58e4
Autor:
Yasushi Kishimoto, Moritoshi Hirono, Ryuichiro Atarashi, Suehiro Sakaguchi, Tohru Yoshioka, Shigeru Katamine, Yutaka Kirino
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60627 (2013)
Mice lacking the prion protein (PrP(C)) gene (Prnp), Ngsk Prnp (0/0) mice, show late-onset cerebellar Purkinje cell (PC) degeneration because of ectopic overexpression of PrP(C)-like protein (PrPLP/Dpl). Because PrP(C) is highly expressed in cerebell
Externí odkaz:
https://doaj.org/article/d8ed7a743f734cf29c4f29ac5731bc56
Autor:
Moritoshi Hirono, Fumihito Saitow, Moeko Kudo, Hidenori Suzuki, Yuchio Yanagawa, Masahisa Yamada, Soichi Nagao, Shiro Konishi, Kunihiko Obata
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29663 (2012)
Inhibitory interneurons in the cerebellar granular layer are more heterogeneous than traditionally depicted. In contrast to Golgi cells, which are ubiquitously distributed in the granular layer, small fusiform Lugaro cells and globular cells are loca
Externí odkaz:
https://doaj.org/article/691052ee111942189c933a8585632166
Autor:
Masayuki Ikeda, Moritoshi Hirono, Takashi Sugiyama, Takahiro Moriya, Masami Ikeda-Sagara, Naomi Eguchi, Yoshihiro Urade, Tohru Yoshioka
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7737 (2009)
BACKGROUND: THE SLEEP SEQUENCE: i) non-REM sleep, ii) REM sleep, and iii) wakefulness, is stable and widely preserved in mammals, but the underlying mechanisms are unknown. It has been shown that this sequence is disrupted by sudden REM sleep onset d
Externí odkaz:
https://doaj.org/article/cd32849905e54f928179410f52ab3880
Autor:
Moritoshi Hirono, Yuchio Yanagawa
Publikováno v:
Journal of Neuroscience Research. 99:898-913
Endocannabinoids (eCBs) act as ubiquitous modulators of synaptic transmission via the activation of cannabinoid receptors (CBRs). Cerebellar Purkinje cells (PCs) make strong inhibitory synaptic contacts not only with neurons in the deep cerebellar nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d301704f15fb44224a0d857e9d4909b8
https://doi.org/10.1002/jnr.24765
https://doi.org/10.1002/jnr.24765
Autor:
Moritoshi Hirono
Publikováno v:
Contemporary Clinical Neuroscience ISBN: 9783030758165
Perineuronal nets (PNNs), which are condensed glycosaminoglycan-rich extracellular matrix structures, surround cell bodies, proximal dendrites, and axon initial segments of neurons in the central nervous system. Digestion of PNNs demonstrated that PN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf1f2c1aba543a7c108f5233efedeab4
https://doi.org/10.1007/978-3-030-75817-2_8
https://doi.org/10.1007/978-3-030-75817-2_8
