Cancer-Cell-Selective Targeting by Arylcyclopropylamine-Vorinostat Conjugates

Autor: Ota, Yosuke, Itoh, Yukihiro, Kurohara, Takashi, Singh, Ritesh, Elboray, Elghareeb E., Hu, Chenliang, Zamani, Farzad, Mukherjee, Anirban, Takada, Yuri, Yamashita, Yasunobu, Morita, Mie, Horinaka, Mano, Sowa, Yoshihiro, Masuda, Mitsuharu, Sakai, Toshiyuki, Suzuki, Takayoshi

Publikováno v: ACS Medicinal Chemistry Letters. 13(10):1568-1573

Yosuke Ota, Yukihiro Itoh, Takashi Kurohara, Ritesh Singh, Elghareeb E. Elboray, Chenliang Hu, Farzad Zamani, Anirban Mukherjee, Yuri Takada, Yasunobu Yamashita, Mie Morita, Mano Horinaka, Yoshihiro Sowa, Mitsuharu Masuda, Toshiyuki Sakai, and Takayo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::984ee264998e6eb3a0d87afe835038f9
https://hdl.handle.net/11094/89872

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Blockage of the mevalonate pathway overcomes the apoptotic resistance to MEK inhibitors with suppressing the activation of Akt in cancer cells.

Autor: Iizuka-Ohashi M; Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Division of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Watanabe M; Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan., Sukeno M; Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan., Morita M; Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan., Hoang NTH; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan., Kuchimaru T; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan., Kizaka-Kondoh S; Department of Life Science and Technology, School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan., Sowa Y; Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan., Sakaguchi K; Division of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Taguchi T; Division of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan., Sakai T; Department of Molecular-Targeting Cancer Prevention, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Publikováno v: Oncotarget [Oncotarget] 2018 Apr 13; Vol. 9 (28), pp. 19597-19612. Date of Electronic Publication: 2018 Apr 13 (Print Publication: 2018).