Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Morioh Kusakabe"'
Publikováno v:
Genes to Cells. 25:86-99
Neurotrophic signaling regulates neural cell behaviors in development and physiology, although its role in regeneration has not been fully investigated. Here, we examined the role of neurotrophic signaling in Xenopus laevis tadpole tail regeneration.
Publikováno v:
Journal of Biological Chemistry. 293:8342-8361
Epithelia contribute to physical barriers that protect internal tissues from the external environment and also support organ structure. Accordingly, establishment and maintenance of epithelial architecture are essential for both embryonic development
Publikováno v:
Genes to Cells. 20:324-339
Cannabinoid receptor interacting protein 1 (CNRIP1), which has been originally identified as the binding partner of cannabinoid receptor 1 (CNR1), is evolutionarily conserved throughout vertebrates, but its physiological function has been unknown. He
Publikováno v:
Nature Communications. 6
Cilia are essential for embryogenesis and maintenance of homeostasis, but little is known about the signalling pathways that regulate ciliogenesis. Here, we identify ERK7, an atypical mitogen-activated protein kinase, as a key regulator of ciliogenes
Autor:
Hiroshi Hanafusa, Norihisa Masuyama, Morioh Kusakabe, Hiroaki Yamanaka, Eisuke Nishida, Takayuki Yasunaga
Publikováno v:
Genes to Cells. 10:369-379
It has been suggested that ILK (integrin-linked kinase) participates in integrin- and growth factor-mediated signaling pathways and also functions as a scaffold protein at cell–extracellular matrix (ECM) adhesion sites. As the recently reported ILK
Publikováno v:
Developmental Cell. 7:33-44
Spatiotemporal control of the Ras/ERK MAP kinase signaling pathway is among the key mechanisms for regulating a wide variety of cellular processes. In this study, we report that human Sef (hSef), a recently identified inhibitor whose action mechanism
Publikováno v:
Nature communications. 6
Cell fate specifications of multiciliate cells (MCCs) and ionocytes are commonly suppressed by the Notch pathway in developing epithelia, but are governed by different master regulators, suggesting the existence of a common regulator linking the Notc
Publikováno v:
EMBO reports. 1:32-39
Although a number of genes that are involved in the establishment of left-right asymmetry have been identified, earlier events in the molecular pathway developing left-right asymmetry remain to be elucidated. Here we present evidence suggesting that
Publikováno v:
Development (Cambridge, England). 139(16)
Sox9 acts together with Sox5 or Sox6 as a master regulator for chondrogenesis; however, the inter-relationship among these transcription factors remains unclear. Here, we show that the protein kinase MLTK plays an essential role in the onset of chond
Publikováno v:
Science signaling. 4(156)
A balance between cell survival and apoptosis is essential for animal development. Although proper development involves multiple interactions between germ layers, little is known about the intercellular and intertissue signaling pathways that promote