Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Morio Ueno"'
Autor:
Morio Ueno, MD, PhD, Kengo Yoshii, PhD, Tomoko Yamashita, PhD, Kazuhiro Sonomura, PhD, Kazuko Asada, BEng, Eiko Ito, BSci, Tomoko Fujita, BEd, Chie Sotozono, MD, PhD, Shigeru Kinoshita, MD, PhD, Junji Hamuro, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100299- (2023)
Purpose: The purpose of the study was to clarify the interplay between metabolites and microRNAs (miRs) in the aqueous humor (AqH) of bullous keratopathy (BK) patients to retain human corneal endothelium (HCE) integrity. Design: Prospective, comparat
Externí odkaz:
https://doaj.org/article/cabf9c0d46004751afc2079ae9d7e9ea
Autor:
Munetoyo Toda, Morio Ueno, Jun Yamada, Asako Hiraga, Kazuko Asada, Junji Hamuro, Chie Sotozono, Shigeru Kinoshita
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract This study aims to clarify the immunogenicity in acquired and innate immune responses of cultured human corneal endothelial cells (hCECs) applied for cell injection therapy, a newly established modality for corneal endothelium failures. Thir
Externí odkaz:
https://doaj.org/article/0ac3782f0d1648d4906ef7600e52e045
Autor:
Yasufumi Tomioka, Koji Kitazawa, Hideki Fukuoka, Morio Ueno, Noriko Koizumi, Chie Sotozono, Shigeru Kinoshita
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 30, Iss , Pp 101839- (2023)
Purpose: To report the safety, efficacy, and long-term outcome in a case of Fuchs endothelial corneal dystrophy (FECD) treated by Rho-associated protein kinase (ROCK)-inhibitor eye drops in combination with removal of degenerated corneal endothelial
Externí odkaz:
https://doaj.org/article/2c070629582049868a3d848b39ff53d5
Autor:
Koji Kitazawa, MD, PhD, Munetoyo Toda, PhD, Morio Ueno, MD, Asako Uehara, Chie Sotozono, MD, PhD, Shigeru Kinoshita, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 2, Pp 100239- (2023)
Purpose: Corneal endothelial cell density (ECD) gradually decreases after corneal transplantation by unknown biologic, biophysical, or immunologic mechanism. Our purpose was to assess the association between donor corneal endothelial cell (CEC) matur
Externí odkaz:
https://doaj.org/article/b97150f0a35149c9b8f3a1b37954109e
Autor:
Hideto Deguchi, Tomoko Yamashita, Nao Hiramoto, Yohei Otsuki, Atsushi Mukai, Morio Ueno, Chie Sotozono, Shigeru Kinoshita, Junji Hamuro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract This study aimed to uncover the mechanism responsible for the clinical efficacy of cell injection therapy with fully differentiated cultured cells. Analysis of polarized expression of ion transporters on cultured human corneal endothelial ce
Externí odkaz:
https://doaj.org/article/90321856ceb94fd58470874fa3fdc7a0
Cellular Interplay Through Extracellular Vesicle miR-184 Alleviates Corneal Endothelium Degeneration
Autor:
Tomoko Yamashita, PhD, Kazuko Asada, BEng, Morio Ueno, MD, PhD, Nao Hiramoto, PhD, Tomoko Fujita, BEd, Munetoyo Toda, PhD, Chie Sotozono, MD, PhD, Shigeru Kinoshita, MD, PhD, Junji Hamuro, PhD
Publikováno v:
Ophthalmology Science, Vol 2, Iss 4, Pp 100212- (2022)
Objective: The objective of the study was to reveal the presence of cellular interplay through extracellular vesicle (EV) microRNAs (miRs), to dampen the vicious cycle to degenerate human corneal endothelium (HCE) tissues. Design: Prospective, compar
Externí odkaz:
https://doaj.org/article/aa52be25f2df4ba9b6960edbc26679ba
Autor:
Takahiko Sato, Koki Higashioka, Hidetoshi Sakurai, Takuya Yamamoto, Naoki Goshima, Morio Ueno, Chie Sotozono
Publikováno v:
Stem Cell Reports, Vol 13, Iss 2, Pp 352-365 (2019)
Summary: The use of adult skeletal muscle stem cells (MuSCs) for cell therapy has been attempted for decades, but still encounters considerable difficulties. MuSCs derived from human induced pluripotent stem cells (hiPSCs) are promising candidates fo
Externí odkaz:
https://doaj.org/article/6938615ffeda48bca05e020514337469
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 19, Iss , Pp 100782- (2020)
Purpose: To report a particular circumstance that led to the abnormal complication of choroidal detachment (CD)-induced secondary angle-closure after trabeculectomy with mitomycin C (MMC). Observations: An 82-year-old Japanese male patient with under
Externí odkaz:
https://doaj.org/article/9307af819b394b928b7688e8b7b5f6c7
Autor:
Yoichi Sunagawa, Masafumi Funamoto, Shogo Sono, Kana Shimizu, Satoshi Shimizu, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka, Eriko Morimoto, Morio Ueno, Maki Komiyama, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 136, Iss 4, Pp 212-217 (2018)
The natural compound, curcumin (CUR), possesses several pharmacological properties, including p300-specific histone acetyltransferase (HAT) inhibitory activity. In our previous study, we demonstrated that CUR could prevent the development of cardiac
Externí odkaz:
https://doaj.org/article/466bb888092b41d9b00f70db1ef7f77c
Autor:
Naoki Okumura, Munetoyo Toda, Kohsaku Numa, John Bush, Motomu Tanaka, Noriko Koizumi, Junji Hamuro, Akihisa Yamamoto, Kojiro Imai, Shigeru Kinoshita, Hiroshi Tanaka, Chie Sotozono, Satoshi Teramukai, Morio Ueno
Publikováno v:
American Journal of Ophthalmology. 237:267-277
PURPOSE To investigate the safety and efficacy of cultured human corneal endothelial cell (hCEC)-injection therapy with mature differentiated (mature) cell subpopulations (SPs) for corneal endothelial failure (CEF). DESIGN Comparative, interventional