Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Morio Arai"'
Autor:
Keisuke Komatsuya, Masaki Ishikawa, Norihito Kikuchi, Tetsuya Hirabayashi, Ryo Taguchi, Naomasa Yamamoto, Morio Arai, Kohji Kasahara
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 69 (2023)
Platelet lipid rafts are critical membrane domains for adhesion, aggregation, and clot retraction. Lipid rafts are isolated as a detergent-resistant membrane fraction via sucrose density gradient centrifugation. The platelet detergent-resistant membr
Externí odkaz:
https://doaj.org/article/5cb9c7835042435b8a60cc8ff315dbd4
Autor:
Hiroko Ohtsuka, Tomohiro Iguchi, Moyuru Hayashi, Mizuho Kaneda, Kazuko Iida, Motoyuki Shimonaka, Takahiko Hara, Morio Arai, Yuichi Koike, Naomasa Yamamoto, Kohji Kasahara
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169609 (2017)
Stromal cell-derived factor-1α (SDF-1α)-induced platelet aggregation is mediated through its G protein-coupled receptor CXCR4 and phosphatidylinositol 3 kinase (PI3K). Here, we demonstrate that SDF-1α induces phosphorylation of Akt at Thr308 and S
Externí odkaz:
https://doaj.org/article/55386a5e5065438fa2ee3d0bb64ca9c2
Publikováno v:
International Journal of General Medicine
Hitoshi Ueda,1 Misato Toyoda,1 Morio Arai,2 Michio Sakai3 1Japan Medical Office, Takeda Pharmaceutical Company Limited, Tokyo, Japan; 2Takeda Development Center-Japan, Takeda Pharmaceutical Company Limited, Tokyo, Japan; 3Pediatrics Department, Munak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a135fa584bc268977a3a223327dd6ed3
https://doi.org/10.2147/ijgm.s272251
https://doi.org/10.2147/ijgm.s272251
Autor:
Katsuyuki Fukutake, Hiroshi Takagi, Werner Engl, Junki Takamatsu, Tadashi Matsushita, Morio Arai, Midori Shima, Akira Shirahata, Haruhiko Uchikawa, Keiji Nogami, Akira Yoshioka, Masashi Taki
Publikováno v:
International Journal of Hematology. 109:336-345
Rurioctocog alfa (recombinant Factor VIII: AdvateⓇ) is available for the control of bleeding in patients with hemophilia A in Japan. To evaluate the immunogenicity, safety, and efficacy of prophylactic and on-demand use of rurioctocog alfa, postmar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c465bfe3b4f44bef2f756d10a51f8c31
https://doi.org/10.1007/s12185-018-02574-x
https://doi.org/10.1007/s12185-018-02574-x
Autor:
Masashi Taki, Katsuyuki Fukutake, Tadashi Matsushita, Keiji Nogami, Midori Shima, Akira Yoshioka, Junki Takamatsu, Morio Arai, Hiroshi Takagi, Haruhiko Uchikawa, Werner Engl, Akira Shirahata
Publikováno v:
International Journal of Hematology. 109:70-78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f219b33d439db46f19eb8b2a8a9249a
https://doi.org/10.1007/s12185-018-2499-y
https://doi.org/10.1007/s12185-018-2499-y
Autor:
Katsuyuki Fukutake, Morio Arai, Hiroshi Takagi, Keiji Nogami, Hideyuki Takedani, Junki Takamatsu, Midori Shima, Masashi Taki, Tadashi Matsushita, Haruhiko Uchikawa, Akira Shirahata, Akira Yoshioka, Werner Engl
Publikováno v:
International Journal of Hematology. 108:22-29
Rurioctocog alfa (recombinant factor VIII: Advate®) is available for the control of bleeding among patients with hemophilia A in Japan. To evaluate the perioperative safety and hemostatic efficacy of Advate®, a postmarketing surveillance was conduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4498bfe4b0a69c2467a24b7ed666ff35
https://doi.org/10.1007/s12185-018-2434-2
https://doi.org/10.1007/s12185-018-2434-2
Autor:
Katsuyuki, Fukutake, Masashi, Taki, Tadashi, Matsushita, Keiji, Nogami, Midori, Shima, Akira, Yoshioka, Junki, Takamatsu, Haruhiko, Uchikawa, Hiroshi, Takagi, Morio, Arai, Werner, Engl, Akira, Shirahata
Publikováno v:
International journal of hematology. 109(1)
Rurioctocog alfa (recombinant factor VIII: Advate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::14c1ab3c6fd156d8a867767eb7861c36
https://pubmed.ncbi.nlm.nih.gov/30560315
https://pubmed.ncbi.nlm.nih.gov/30560315
Autor:
Midori Shima, Tadashi Matsushita, Haruhiko Uchikawa, Teruhisa Fujii, Katsuyuki Fukutake, Tetsuji Sato, Michio Sakai, Werner Engl, Brigitt E. Abbuehl, Barbara A. Konkle, Masashi Taki, Morio Arai, Keiji Nogami, Satoshi Higasa
Publikováno v:
International journal of hematology. 106(5)
Rurioctocog alfa pegol (BAX 855) is a novel third-generation recombinant factor VIII whose active ingredient is chemically modified with polyethylene glycol. A global multicenter phase 2/3 study of the product in 137 patients (including 11 patients f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61879b01d63ee79f851e57a6d0022dfc
https://pubmed.ncbi.nlm.nih.gov/29149425
https://pubmed.ncbi.nlm.nih.gov/29149425
Autor:
Tomohiro Iguchi, Moyuru Hayashi, Kohji Kasahara, Naomasa Yamamoto, Kazuko Iida, Morio Arai, Yuichi Koike, Takahiko Hara, Motoyuki Shimonaka, Mizuho Kaneda, Hiroko Ohtsuka
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0169609 (2017)
PLoS ONE, Vol 12, Iss 1, p e0169609 (2017)
Stromal cell-derived factor-1α (SDF-1α)-induced platelet aggregation is mediated through its G protein-coupled receptor CXCR4 and phosphatidylinositol 3 kinase (PI3K). Here, we demonstrate that SDF-1α induces phosphorylation of Akt at Thr308 and S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca1a0b63616233c582d0c8316868d90
http://europepmc.org/articles/PMC5224795
http://europepmc.org/articles/PMC5224795
Autor:
Yoichi Sakata, Hideki Uchiumi, Tadashi Matsushita, Keiji Nogami, Takashi Suzuki, Kazuo Kawasugi, Midori Shima, Hideji Hanabusa, Teruhisa Fujii, Yasuo Horikoshi, Morio Arai
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 25:75-81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af758e9e64591d4affe32fa776a5a34
https://doi.org/10.2491/jjsth.25.75
https://doi.org/10.2491/jjsth.25.75