Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Morimichi Sato"'
Autor:
Makoto Kawai, Yoshinori Murata, Mio Sakai, Atsushi Omura, Kazunari Hattori, Shinichi Sakemi, Yoko Matsuoka, Ivan J. Samardjiev, Jon Bordner, Morimichi Sato, Takashi Kojima, Takashi Mano
Publikováno v:
International Journal of Pharmaceutics. 355:337-340
(−)-6-{2-[4-(3-Fluorophenyl)-4-hydroxy-piperidin-1-yl]-1-hydroxyethyl}-3,4-dihydro-quinolin-2(1H)-one (compound A) is an NR2B selective N -methyl d -aspartate (NMDA) antagonist that has shown at least two polymorphs, forms I and II. In this report,
Autor:
Kiyohiko Sugano, Yohei Kawabata, Morimichi Sato, Satomi Onoue, Takashi Mano, Takashi Kojima, Noriaki Murase
Publikováno v:
International journal of pharmaceutics. 350(1-2)
From discovery synthesis of a zwitterionic pharmaceutical compound, 4-{[4-({[(3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl]amino}methyl)piperidin-1-yl]methyl}tetrahydro-2H-pyran-4-carboxylic acid (compound A), two anhydrous ZW-I and ZW