Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Morimasa, Wada"'
Publikováno v:
International Journal of Fertility and Sterility, Vol 13, Iss 3, Pp 245-249 (2019)
Actins play essential roles in cellular morphogenesis. In mice, the T-actin1 and 2 genes, which encode actin-like proteins, are specifically expressed in haploid germ cells. Both T-ACTIN1/ACTLB and T-ACTIN2/ACTL7A have also been cloned and studied. T
Externí odkaz:
https://doaj.org/article/930a2a900323432cb43c614eb1832649
Autor:
Hisayo Nishida-Fukuda, Keizo Tokuhiro, Yukio Ando, Hiroaki Matsushita, Morimasa Wada, Hiromitsu Tanaka
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249912 (2021)
HASPIN is a serine/threonine kinase that regulates mitosis by phosphorylating histone H3 at threonine 3. The expression levels of HASPIN in various cancers are associated with tumor malignancy and poor survival, suggesting that HASPIN inhibition may
Externí odkaz:
https://doaj.org/article/971e560ede6544d8ba3b85b8214cf81c
Autor:
Morimasa Wada
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 142(11)
ATP-binding cassette (ABC) transporters, which comprise the largest gene-family in humans, are membrane proteins that transport various substrates, depending on ATP hydrolysis. Among these transporters, several include ABCB1 (P-glycoprotein), identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fdb353c0f896eb5213ae96953da8a2
https://pubmed.ncbi.nlm.nih.gov/36328450
https://pubmed.ncbi.nlm.nih.gov/36328450
Autor:
Junji Tsuchida, Morimasa Wada, Yoshifumi Kawamura, Masahito Ikawa, Hidenobu Okuda, Kei Yamaguchi, Virginia Smith Shapiro, Naoki Goshima, Shinichiro Fukuhara, Akira Tsujimura, Yoshitake Nishimune, Mieko Takasaka, Yoshitaka Kawakami, Eriko Fukuda, Hiromitsu Tanaka, Yasushi Miyagawa, Yuki Okada, Ayako Isotani
Publikováno v:
Genes to Cells. 26:180-189
TRA98 is a rat monoclonal antibody (mAb) which recognizes a specific antigen in the nuclei of germ cells. mAb TRA98 has been used to understand the mechanism of germ cell development and differentiation in many studies. In mice, the antigen recognize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f91b4de02c5b7b4e47c6ab8c63a3680
https://doi.org/10.1111/gtc.12832
https://doi.org/10.1111/gtc.12832
Autor:
Hidenobu Okuda, Hiroshi Kiuchi, Tetsuya Takao, Yasushi Miyagawa, Akira Tsujimura, Norio Nonomura, Haruhiko Miyata, Masaru Okabe, Masahito Ikawa, Yoshitaka Kawakami, Naoki Goshima, Morimasa Wada, Hiromitsu Tanaka
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124293 (2015)
Spermatogenesis is an elaborately regulated system dedicated to the continuous production of spermatozoa via the genesis of spermatogonia. In this process, a variety of genes are expressed that are relevant to the differentiation of germ cells at eac
Externí odkaz:
https://doaj.org/article/96d51e70fde64b8f984e57a51c836ab2
Autor:
Hiromitsu, Tanaka, Hisayo, Nishida-Fukuda, Morimasa, Wada, Keizo, Tokuhiro, Hiroaki, Matsushita, Yukio, Ando
Publikováno v:
Cell journal. 24(4)
HASPIN acts in chromosome segregation via histone phosphorylation. Recently, HASPIN inhibitors have been shown to suppress growth of various cancer cells. Pancreatic cancer has no symptom in the early stages and may progress before detection. So, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00c44e6e3cfbf1d37c90452e80e32e67
https://pubmed.ncbi.nlm.nih.gov/35674022
https://pubmed.ncbi.nlm.nih.gov/35674022
Autor:
Morimasa Wada, Kazuhiro Kaseda, Yusuke Aoki, Hidenobu Okuda, Shigeo Horie, Moira K O'Bryan, Hiromitsu Tanaka, Yoshitake Nishimune, Keizo Tokuhiro, Kouichi Kitamura, Tomoe Ohta, Tsukasa Fujiki, Akira Tsujimura, Yukiko Ogawa, Masaru Okabe
Publikováno v:
Molecular reproduction and developmentREFERENCES. 87(5)
Haprin (TRIM36) is a ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. It is expressed in the testes in both mice and humans and is thought to be involved in spermiogenesis, the acrosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbe5c704c0c8181f5610d4dfc20fa37
https://pubmed.ncbi.nlm.nih.gov/32311190
https://pubmed.ncbi.nlm.nih.gov/32311190
Autor:
Hidenobu Okuda, Akira Tsujimura, Shinji Irie, Keisuke Yamamoto, Shinichiro Fukuhara, Yasuhiro Matsuoka, Tetsuya Takao, Yasushi Miyagawa, Norio Nonomura, Morimasa Wada, Hiromitsu Tanaka
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35195 (2012)
The development of novel fertilization treatments, including in vitro fertilization and intracytoplasmic injection, has made pregnancy possible regardless of the level of activity of the spermatozoa; however, the etiology of male-factor infertility i
Externí odkaz:
https://doaj.org/article/f0ab4988b72f4bd693b7690ec706f362
Autor:
Keizo Tokuhiro, Ayako Isotani, Sadaki Yokota, Yoshihisa Yano, Shigeru Oshio, Mika Hirose, Morimasa Wada, Kyoko Fujita, Yukiko Ogawa, Masaru Okabe, Yoshitake Nishimune, Hiromitsu Tanaka
Publikováno v:
PLoS Genetics, Vol 5, Iss 11, p e1000712 (2009)
Polyamines are known to play important roles in the proliferation and differentiation of many types of cells. Although considerable amounts of polyamines are synthesized and stored in the testes, their roles remain unknown. Ornithine decarboxylase an
Externí odkaz:
https://doaj.org/article/6738a59ffb7e422eb3895f608bbbe737
Publikováno v:
European Journal of Cancer Prevention
HASPIN has been identified as a nuclear Ser/Thr kinase specifically expressed in haploid germ cells. HASPIN kinase inhibitors were recently isolated, and their antitumor activity reported. Colorectal cancer occurs with high incidence worldwide. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac66a026632cd2d2cc9bd07e52682d5c
https://pubmed.ncbi.nlm.nih.gov/31833958
https://pubmed.ncbi.nlm.nih.gov/31833958