Klebsiella pneumoniae causes bacteremia using factors that mediate tissue-specific fitness and resistance to oxidative stress.

Autor: Holmes CL; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America., Wilcox AE; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America., Forsyth V; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America., Smith SN; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America., Moricz BS; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America., Unverdorben LV; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America., Mason S; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America., Wu W; Bioinformatics Core Facility, School of Medicine, University of Michigan, Ann Arbor, Michigan, United States of America., Zhao L; Research Institute, Beaumont Hospital, Royal Oak, Michigan, United States of America., Mobley HLT; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America., Bachman MA; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2023 Jul 18; Vol. 19 (7), pp. e1011233. Date of Electronic Publication: 2023 Jul 18 (Print Publication: 2023).

On-demand biomanufacturing of protective conjugate vaccines.

Autor: Stark JC; Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Rd Technological Institute E136, Evanston, IL 60208-3120, USA.; Center for Synthetic Biology, Northwestern University, 2145 Sheridan Rd Technological Institute E136, Evanston, IL 60208-3120, USA.; Chemistry of Life Processes Institute, Northwestern University, 2170 Campus Drive, Evanston, IL 60208-3120, USA., Jaroentomeechai T; Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853, USA., Moeller TD; Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853, USA., Hershewe JM; Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Rd Technological Institute E136, Evanston, IL 60208-3120, USA.; Center for Synthetic Biology, Northwestern University, 2145 Sheridan Rd Technological Institute E136, Evanston, IL 60208-3120, USA.; Chemistry of Life Processes Institute, Northwestern University, 2170 Campus Drive, Evanston, IL 60208-3120, USA., Warfel KF; Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Rd Technological Institute E136, Evanston, IL 60208-3120, USA.; Center for Synthetic Biology, Northwestern University, 2145 Sheridan Rd Technological Institute E136, Evanston, IL 60208-3120, USA.; Chemistry of Life Processes Institute, Northwestern University, 2170 Campus Drive, Evanston, IL 60208-3120, USA., Moricz BS; Department of Microbiology and Immunology, University of Iowa, 51 Newton Rd 3-403 Bowen Science Building, Iowa City, IA 52242, USA., Martini AM; Department of Microbiology and Immunology, University of Iowa, 51 Newton Rd 3-403 Bowen Science Building, Iowa City, IA 52242, USA., Dubner RS; Department of Biological Sciences, Northwestern University, 2205 Tech Drive Hogan Hall 2144, Evanston, IL 60208-3500, USA., Hsu KJ; Department of Mechanical Engineering, Northwestern University, 2145 Sheridan Rd Technological Institute B224, Evanston, IL 60208-3120, USA., Stevenson TC; Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Weill Hall, Ithaca, NY 14853, USA., Jones BD; Department of Microbiology and Immunology, University of Iowa, 51 Newton Rd 3-403 Bowen Science Building, Iowa City, IA 52242, USA.; Graduate Program in Genetics, 431 Newton Rd, University of Iowa, Iowa City, IA 52242, USA., DeLisa MP; Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, 120 Olin Hall, Ithaca, NY 14853, USA. md255@cornell.edu m-jewett@northwestern.edu.; Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Weill Hall, Ithaca, NY 14853, USA., Jewett MC; Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Rd Technological Institute E136, Evanston, IL 60208-3120, USA. md255@cornell.edu m-jewett@northwestern.edu.; Center for Synthetic Biology, Northwestern University, 2145 Sheridan Rd Technological Institute E136, Evanston, IL 60208-3120, USA.; Chemistry of Life Processes Institute, Northwestern University, 2170 Campus Drive, Evanston, IL 60208-3120, USA.; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 676 N. St Clair St, Suite 1200, Chicago, IL 60611-3068, USA.; Simpson-Querrey Institute, Northwestern University, 303 E. Superior St, Suite 11-131 Chicago, IL 60611-2875, USA.

Publikováno v: Science advances [Sci Adv] 2021 Feb 03; Vol. 7 (6). Date of Electronic Publication: 2021 Feb 03 (Print Publication: 2021).