Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Morichika, Konishi"'
Autor:
Hironari Nishizawa, Mitsuyo Matsumoto, Mie Yamanaka, Riko Irikura, Kazuma Nakajima, Keisuke Tada, Yoshiaki Nakayama, Morichika Konishi, Nobuyuki Itoh, Ryo Funayama, Keiko Nakayama, Kazuhiko Igarashi
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114403- (2024)
Summary: Ferroptosis is a type of regulated cell death characterized by iron-dependent lipid peroxidation. A model cell system is constructed to induce ferroptosis by re-expressing the transcription factor BACH1, a potent ferroptosis inducer, in immo
Externí odkaz:
https://doaj.org/article/e99568b0d1834b299cd30115e6501227
Autor:
Yoshiaki Nakayama, Yuki Masuda, Takehiro Mukae, Tadahisa Mikami, Ryohei Shimizu, Naoto Kondo, Hiroshi Kitagawa, Nobuyuki Itoh, Morichika Konishi
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Neudesin, originally identified as a neurotrophic factor, has primarily been studied for its neural functions despite its widespread expression. Using 8-week-old neudesin knockout mice, we elucidated the role of neudesin in the spleen. The a
Externí odkaz:
https://doaj.org/article/a1416c4ad5ca4cb78fc60640b2cf62fd
Autor:
Yoshimi Nakagawa, Yunong Wang, Song-iee Han, Kanako Okuda, Asayo Oishi, Yuka Yagishita, Kae Kumagai, Hiroshi Ohno, Yoshinori Osaki, Yuhei Mizunoe, Masaya Araki, Yuki Murayama, Hitoshi Iwasaki, Morichika Konishi, Nobuyuki Itoh, Takashi Matsuzaka, Hirohito Sone, Nobuhiro Yamada, Hitoshi Shimano
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 949-971 (2021)
Background & Aims: cAMP responsive element-binding protein 3 like 3 (CREB3L3) is a membrane-bound transcription factor involved in the maintenance of lipid metabolism in the liver and small intestine. CREB3L3 controls hepatic triglyceride and glucose
Externí odkaz:
https://doaj.org/article/bce56fc30a3344359dbfa3a4b2fbc9ba
Autor:
Aoi Satoh, Song-iee Han, Masaya Araki, Yoshimi Nakagawa, Hiroshi Ohno, Yuhei Mizunoe, Kae Kumagai, Yuki Murayama, Yoshinori Osaki, Hitoshi Iwasaki, Motohiro Sekiya, Morichika Konishi, Nobuyuki Itoh, Takashi Matsuzaka, Hirohito Sone, Hitoshi Shimano
Publikováno v:
iScience, Vol 23, Iss 3, Pp - (2020)
Summary: Mice overexpressing the nuclear form of CREBH mainly in the liver (CREBH-Tg) showed suppression of high-fat high-sucrose (HFHS) diet-induced obesity accompanied by an increase in plasma fibroblast growth factor 21 (FGF21) levels. CREBH overe
Externí odkaz:
https://doaj.org/article/d7967aadf1e240c7bf75f7b3a6059d4c
Autor:
Xunmei Yuan, Kazutaka Tsujimoto, Koshi Hashimoto, Kenichi Kawahori, Nozomi Hanzawa, Miho Hamaguchi, Takami Seki, Makiko Nawa, Tatsuya Ehara, Yohei Kitamura, Izuho Hatada, Morichika Konishi, Nobuyuki Itoh, Yoshimi Nakagawa, Hitoshi Shimano, Takako Takai-Igarashi, Yasutomi Kamei, Yoshihiro Ogawa
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
FGF21 exerts beneficial metabolic effects on multiple tissues. Here the authors show that the Fgf21 gene is demethylated during the postnatal suckling period, creating an epigenetic memory that determines the responsiveness of the Fgf21 gene to induc
Externí odkaz:
https://doaj.org/article/c62f55c79e3144f582a03839a050d571
Autor:
Saori, Hokari, Sachiko, Chikahisa, Tetsuya, Shiuchi, Yoshiaki, Nakayama, Morichika, Konishi, Seiji, Nishino, Nobuyuki, Itoh, Hiroyoshi, Séi
Publikováno v:
Brain Research Bulletin. 191:40-47
Although several previous studies have suggested a relationship between sleep and the stress response, the mechanism underlying this relationship remains largely unknown. Here, we show that fibroblast growth factor 21 (FGF21), a lipid metabolism-rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f5eec4d9864c468cb4eb446bb3aaa9
https://doi.org/10.1016/j.brainresbull.2022.10.005
https://doi.org/10.1016/j.brainresbull.2022.10.005
Autor:
Mayu Kasubuchi, Keita Watanabe, Kanako Hirano, Daisuke Inoue, Xuan Li, Kazuya Terasawa, Morichika Konishi, Nobuyuki Itoh, Ikuo Kimura
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Recently, sex steroid membrane receptors garnered world-wide attention because they may be related to sex hormone-mediated unknown rapid non-genomic action that cannot be currently explained by their genomic action via nuclear receptors. Pro
Externí odkaz:
https://doaj.org/article/70a86be7233e44a391cf7494a926ab91
Autor:
Yoshiaki Nakayama, Yuki Masuda, Hiroya Ohta, Tomohiro Tanaka, Miwa Washida, Yo-ichi Nabeshima, Ayumi Miyake, Nobuyuki Itoh, Morichika Konishi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract We have previously shown that Fibroblast growth factor 21 (Fgf21) is expressed in the thymus as well as in the liver. In line with this expression profile, Fgf21 was recently reported to protect against ageing-related thymic senescence by im
Externí odkaz:
https://doaj.org/article/ab15cf9ac9a2451b8be4e3b3c081e623
Publikováno v:
Biologicalpharmaceutical bulletin. 45(12)
Neudesin is a secretory protein involved in the brain development during embryonic period and diet-induced development of adipose tissue. Although neudesin is also expressed in the testis, its physiological functions in the testis have not been docum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c38cf19900f30316326f375a4166d9a
https://pubmed.ncbi.nlm.nih.gov/36450531
https://pubmed.ncbi.nlm.nih.gov/36450531
Autor:
Ayumi Miyake, Yoko Mekata, Hidenori Fujibayashi, Kazuya Nakanishi, Morichika Konishi, Nobuyuki Itoh
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176036 (2017)
Bmps regulate numerous neural functions with their regulators. We previously identified Brorin, a neural-specific secreted antagonist of Bmp signaling, in humans, mice, and zebrafish. Mouse Brorin has two cysteine-rich domains containing 10 cysteine
Externí odkaz:
https://doaj.org/article/2853081528204dfc95fd28c38c5c8a06