Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Moriah Gidoni"'
Autor:
Shira Perez, Anat Lavi-Itzkovitz, Moriah Gidoni, Tom Domovitz, Roba Dabour, Ishant Khurana, Ateret Davidovich, Ana Tobar, Alejandro Livoff, Evgeny Solomonov, Yaakov Maman, Assam El-Osta, Yishan Tsai, Ming-Lung Yu, Salomon M. Stemmer, Izhak Haviv, Gur Yaari, Meital Gal-Tanamy
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 1, Pp 63-81 (2023)
Background & Aims: Hepatocellular carcinoma (HCC) is a model of a diverse spectrum of cancers because it is induced by well-known etiologies, mainly hepatitis C virus (HCV) and hepatitis B virus. Here, we aimed to identify HCV-specific mutational sig
Externí odkaz:
https://doaj.org/article/2504d44cdec5437d864285de9108428c
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103192- (2021)
Summary: Inference of germline polymorphisms in immunoglobulin genes from B cell receptor repertoires is complicated by somatic hypermutations, sequencing/PCR errors, and by varying length of reference alleles. The light chain inference is particular
Externí odkaz:
https://doaj.org/article/9853153e0d8f409288a743c7bede360e
Autor:
Moriah Gidoni, Omri Snir, Ayelet Peres, Pazit Polak, Ida Lindeman, Ivana Mikocziova, Vikas Kumar Sarna, Knut E. A. Lundin, Christopher Clouser, Francois Vigneault, Andrew M. Collins, Ludvig M. Sollid, Gur Yaari
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
High-throughput sequencing and analyzes of antibody repertoire provide important information on immune responses, but current methodologies are limited in sequence assembly precision and haplotype inference validity. Here the authors propose a new Ba
Externí odkaz:
https://doaj.org/article/673286972274442fbf2f5824de7b4daa
Autor:
Miri Gordin, Hagit Philip, Alona Zilberberg, Moriah Gidoni, Raanan Margalit, Christopher Clouser, Kristofor Adams, Francois Vigneault, Irun R Cohen, Gur Yaari, Sol Efroni
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008486 (2021)
The partial success of tumor immunotherapy induced by checkpoint blockade, which is not antigen-specific, suggests that the immune system of some patients contain antigen receptors able to specifically identify tumor cells. Here we focused on T-cell
Externí odkaz:
https://doaj.org/article/c1ca83cca5d546b4b5106959d3b93493
Autor:
Daniel Gadala-Maria, Moriah Gidoni, Susanna Marquez, Jason A. Vander Heiden, Justin T. Kos, Corey T. Watson, Kevin C. O'Connor, Gur Yaari, Steven H. Kleinstein
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The adaptive immune receptor repertoire (AIRR) contains information on an individuals' immune past, present and potential in the form of the evolving sequences that encode the B cell receptor (BCR) repertoire. AIRR sequencing (AIRR-seq) studies rely
Externí odkaz:
https://doaj.org/article/77aec0eb5c9449169121d89d6e2e9c84
Autor:
Andrew M. Collins, Ludvig M. Sollid, Ayelet Peres, Francois Vigneault, Gur Yaari, Christopher Clouser, Pazit Polak, Ivana Mikocziova, Moriah Gidoni, Vikas Kumar Sarna, Ida Lindeman, Knut E.A. Lundin, Omri Snir
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Analysis of antibody repertoires by high-throughput sequencing is of major importance in understanding adaptive immune responses. Our knowledge of variations in the genomic loci encoding immunoglobulin genes is incomplete, resulting in conflicting VD
Immunoglobulin loci are rich in germline polymorphisms and identification of novel polymorphic variants can be facilitated by germline inference of B cell receptor repertoires. Germline gene inference is complicated by somatic hypermutations, errors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78f56f599ce68eaf2ec68ac2e0e7367e
https://doi.org/10.1101/2021.02.05.429934
https://doi.org/10.1101/2021.02.05.429934
Autor:
Hagit Philip, Gur Yaari, Kristofor Adams, Irun R. Cohen, Raanan Margalit, Moriah Gidoni, Francois Vigneault, Miri Gordin, Christopher Clouser, Sol Efroni, Alona Zilberberg
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008486 (2021)
PLoS Computational Biology
PLoS Computational Biology
The partial success of tumor immunotherapy induced by checkpoint blockade, which is not antigen-specific, suggests that the immune system of some patients contain antigen receptors able to specifically identify tumor cells. Here we focused on T-cell
Publikováno v:
iScience
iScience, Vol 24, Iss 10, Pp 103192-(2021)
iScience, Vol 24, Iss 10, Pp 103192-(2021)
Summary Inference of germline polymorphisms in immunoglobulin genes from B cell receptor repertoires is complicated by somatic hypermutations, sequencing/PCR errors, and by varying length of reference alleles. The light chain inference is particularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f173682bf6336d0d4bf284f8db380f20
http://hdl.handle.net/10852/91603
http://hdl.handle.net/10852/91603
Autor:
Omri Snir, Ludvig M. Sollid, Ivana Mikocziova, Ayelet Peres, Ida Lindeman, Moriah Gidoni, Gur Yaari
Germline variations in immunoglobulin genes influence the repertoire of B cell receptors and antibodies, and such polymorphisms may impact disease susceptibility. However, the knowledge of the genomic variation of the immunoglobulin loci is scarce. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b69a9f565a00857c5b570c92971d400