Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Morié Ishida"'
Autor:
Alexandra Beilina, Luis Bonet-Ponce, Ravindran Kumaran, Jennifer J. Kordich, Morié Ishida, Adamantios Mamais, Alice Kaganovich, Sara Saez-Atienzar, David C. Gershlick, Dorien A. Roosen, Laura Pellegrini, Vlad Malkov, Matthew J. Fell, Kirsten Harvey, Juan S. Bonifacino, Darren J. Moore, Mark R. Cookson
Publikováno v:
Cell Reports, Vol 31, Iss 5, Pp - (2020)
Summary: Mutations in Leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease (PD). However, the precise function of LRRK2 remains unclear. We report an interaction between LRRK2 and VPS52, a subunit of the Golgi-associated retrograde protei
Externí odkaz:
https://doaj.org/article/8f3645a2b68b47bab2889e3c6b78354d
Autor:
Morié Ishida, María G Otero, Christina Freeman, Pedro A Sánchez-Lara, Carlos M Guardia, Tyler Mark Pierson, Juan S Bonifacino
Publikováno v:
Human Molecular Genetics. 32:1162-1174
ADP-ribosylation factor 1 (ARF1) is a small GTPase that regulates membrane traffic at the Golgi apparatus and endosomes through recruitment of several coat proteins and lipid-modifying enzymes. Here, we report a pediatric patient with an ARF1-related
Autor:
Morié Ishida, Juan S. Bonifacino
Publikováno v:
Journal of Cell Biology. 218:3681-3696
SNARE-mediated fusion of endosome-derived transport carriers with the trans-Golgi network (TGN) depends on the concerted action of two types of tethering factors: long coiled-coil tethers of the golgin family, and the heterotetrameric complex GARP. W
Autor:
Morié Ishida, Mai E. Oguchi, Mitsunori Fukuda, Yoshihiko Kuchitsu, Naonobu Fujita, Paulina S. Wawro, Soujiro Marubashi, Riko Kinoshita, Yuta Homma
Publikováno v:
The Journal of Cell Biology
Rab small GTPases (∼60 genes in mammals) are the master regulators of intracellular membrane trafficking. Homma et al. establish a comprehensive collection of knockout epithelial cell lines for all the mammalian Rabs, revealing that Rab6 is require
Publikováno v:
The Journal of Biological Chemistry. 294:6912-6922
HPS4 biogenesis of lysosome-related organelles complex 3 subunit 2 (HPS4) is one of the genes whose mutations have been associated with Hermansky–Pudlak syndrome (HPS), characterized by ocular albinism and susceptibility to bleeding because of defe
Autor:
Morié Ishida, Juan S. Bonifacino
Publikováno v:
The Journal of Cell Biology
Ishida and Bonifacino show that the small GTPase ARFRP1 functions upstream of two other small GTPases, ARL1 and ARL5, to coordinate the recruitment of two distinct classes of tethering factors, golgins and GARP, respectively, to the trans-Golgi netwo
Autor:
Juan S. Bonifacino, David B. Everman, Allison Bellomo, David C. Gershlick, Morié Ishida, Julie R. Jones
Publikováno v:
Hum Mol Genet
GARP and EARP are related heterotetrameric protein complexes that associate with the cytosolic face of the trans-Golgi network and recycling endosomes, respectively. At these locations, GARP and EARP function to promote the fusion of endosome-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d80c7e18df13302862164414cae738e
https://europepmc.org/articles/PMC6489419/
https://europepmc.org/articles/PMC6489419/
Autor:
David C. Gershlick, Morié Ishida, Dorien A. Roosen, Vlad Malkov, Luis Bonet-Ponce, Ravindran Kumaran, Matthew J. Fell, Alexandra Beilina, Alice Kaganovich, Kirsten Harvey, Jennifer J. Kordich, Juan S. Bonifacino, Sara Saez-Atienzar, Darren J. Moore, Laura Pellegrini, Adamantios Mamais, Mark R. Cookson
Publikováno v:
Cell reports
Cell Reports, Vol 31, Iss 5, Pp-(2020)
Cell Reports, Vol 31, Iss 5, Pp-(2020)
SUMMARY Mutations in Leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease (PD). However, the precise function of LRRK2 remains unclear. We report an interaction between LRRK2 and VPS52, a subunit of the Golgi-associated retrograde protein
Publikováno v:
Archives of Biochemistry and Biophysics. 536:31-37
We previously reported that the small GTPase Rab27 and its effectors regulate isoproterenol (IPR)-stimulated amylase release from rat parotid acinar cells. Although activation of Rab27 by a specific guanine nucleotide exchange factor (GEF) is thought
Publikováno v:
Journal of Biochemistry. :mvw100
Melanosome transfer from melanocytes to surrounding keratinocytes is one of the crucial but less well-characterized steps in the process of skin pigmentation. Although several markers have generally been used to detect melanosomes in melanocytes, no