Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Morgayn I. Read"'
Publikováno v:
Current Medicinal Chemistry. 28:4972-4994
Inflammasome research has primarily focused on neurological tissue, particularly on damaged tissue. Most current neurological literature involves in vivo and in vitro studies utilizing astroglia, as astroglia express the cytoskeletal glial fibrillary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a061e6fd57bfd864d0dadf0de4fde1
https://doi.org/10.2174/0929867328666210301105422
https://doi.org/10.2174/0929867328666210301105422
Autor:
Mohammad Bagherniya, Sanaz Mehrabani, Amirhossein Sahebkar, Gholamreza Askari, Morgayn I. Read
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Mitochondrial dysfunction can be a major cause of a wide range of age‐related diseases. Maintaining the normal homeostasis of mitochondria population plays an important role in ensuring people's health, which is done through the mitophagy process.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1f8f4b234add3f4699f550dc02ad14
https://doi.org/10.1002/jcsm.12611
https://doi.org/10.1002/jcsm.12611
Publikováno v:
Seminars in Arthritis and Rheumatism. 50:769-775
Systemic lupus erythematosus (SLE) is a heterogeneous disease which is characterized with excessive inflammation and autoantibodies, macrophage and complement activation, and subsequently immunologically mediated tissue damage. In spite of improved t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d85ba658dbcbbc973a1017cd7ccfb01
https://doi.org/10.1016/j.semarthrit.2020.05.011
https://doi.org/10.1016/j.semarthrit.2020.05.011
Publikováno v:
IUBMB Life. 72:652-664
Autophagy is a highly conserved cellular degradation process involving lysosomal degradation for the turnover of proteins, protein complexes, and organelles. Defects in autophagy produces impaired intercellular communication and have subsequently bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38c3efc569b12af929d6efb0341a2ab
https://doi.org/10.1002/iub.2209
https://doi.org/10.1002/iub.2209
Autor:
Marco Avila-Rodriguez, Amirhossein Sahebkar, Amir Tajbakhsh, Seyed Mohammad Gheibihayat, Morgayn I. Read, George E. Barreto
Publikováno v:
European journal of pharmacology. 895
Neuronal survival and axonal renewal following central nervous system damage and in neurodegenerative illnesses, such as Alzheimer's disease (AD), can be enhanced by fast clearance of neuronal apoptotic debris, as well as the removal of amyloid beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14deffb6ccdc94e8315ed3d7f508ec6f
https://pubmed.ncbi.nlm.nih.gov/33460611
https://pubmed.ncbi.nlm.nih.gov/33460611
Publikováno v:
IUBMB lifeREFERENCES. 72(11)
The lysosome is a membrane-enclosed organelle in eukaryotic cells, which has basic pattern recognition for nutrient-dependent signal transduction. In Alzheimer's disease, the already declining autophagy-lysosomal function is exacerbated by an increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d1d74a0c439cef19166f24e2120da4
https://pubmed.ncbi.nlm.nih.gov/32894821
https://pubmed.ncbi.nlm.nih.gov/32894821
Autor:
Emma Maria Hinemoa Besley, Scott Duncan George Smart, Jessica Renee Kelly, Ivan A. Sammut, Morgayn I. Read, Joanne C. Harrison, Yimin Yao
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Cardiorenal syndrome, de novo renal pathology arising secondary to cardiac insufficiency, is clinically recognised but poorly characterised. This study establishes and characterises a valid model representative of Type 2 cardiorenal syndrome. Extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0dba36f28321b6720535cf97f2eb89
http://europepmc.org/articles/PMC6985167
http://europepmc.org/articles/PMC6985167
Autor:
D. S. Kerr, Morgayn I. Read, Rebecca N. Millen, Ivan A. Sammut, Joanne C. Harrison, Dominic Michael McCann
Publikováno v:
Epilepsia. 59:854-865
OBJECTIVE Altered autonomic activity has been implicated in the development of cardiac dysfunction during seizures. This study investigates whether intervening in seizure progression with diazepam will reduce seizure-induced cardiomyopathy. Second, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ab6ed41b939a16887dcf3c4b7b786d
https://doi.org/10.1111/epi.14039
https://doi.org/10.1111/epi.14039
Autor:
Armita Mahdavi Gorabi, Hossein Ahmadi Tafti, George E. Barreto, Morgayn I. Read, Amirhossein Sahebkar, Nasim Kiaie
Publikováno v:
Molecular neurobiology. 56(12)
Neurologic complications are commonly regarded as irreversible impairments that stem from limited potential of regeneration of the central nervous system (CNS). On the other side, the regenerative potential of stem cells has been evaluated in basic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a4c3197e8c8ad7ae2894b132e413fb
https://pubmed.ncbi.nlm.nih.gov/31197655
https://pubmed.ncbi.nlm.nih.gov/31197655
Publikováno v:
Neurotoxicity research. 36(1)
Microglia are innate immune system cells which reside in the central nervous system (CNS). Resting microglia regulate the homeostasis of the CNS via phagocytic activity to clear pathogens and cell debris. Sometimes, however, to protect neurons and fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afa63f26030ed3591ad8dd5a999a506
https://pubmed.ncbi.nlm.nih.gov/30949950
https://pubmed.ncbi.nlm.nih.gov/30949950