Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Morgane Thomas"'
Autor:
Ophélie A. Martin, Morgane Thomas, Marie Marquet, Charlotte Bruzeau, Armand Garot, Mylène Brousse, Sébastien Bender, Claire Carrion, Jee Eun Choi, Bao Q. Vuong, Patricia J. Gearhart, Robert W. Maul, Sandrine Le Noir, Eric Pinaud
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntoductionTwo scaffold/matrix attachment regions (5’- and 3’-MARsEµ) flank the intronic core enhancer (cEµ) within the immunoglobulin heavy chain locus (IgH). Besides their conservation in mice and humans, the physiological role of MARsEµ is
Externí odkaz:
https://doaj.org/article/1ce217207e1e471da5b5f04499b868f6
Autor:
Walter Santana-Garcia, Maria Rocha-Acevedo, Lucia Ramirez-Navarro, Yvon Mbouamboua, Denis Thieffry, Morgane Thomas-Chollier, Bruno Contreras-Moreira, Jacques van Helden, Alejandra Medina-Rivera
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 1415-1428 (2019)
Gene regulatory regions contain short and degenerated DNA binding sites recognized by transcription factors (TFBS). When TFBS harbor SNPs, the DNA binding site may be affected, thereby altering the transcriptional regulation of the target genes. Such
Externí odkaz:
https://doaj.org/article/440bf9b4109f479b801230395cb4a6a1
Autor:
Catherine Ouk, Lilian Roland, Nathalie Gachard, Stéphanie Poulain, Christelle Oblet, David Rizzo, Alexis Saintamand, Quentin Lemasson, Claire Carrion, Morgane Thomas, Karl Balabanian, Marion Espéli, Marie Parrens, Isabelle Soubeyran, Mélanie Boulin, Nathalie Faumont, Jean Feuillard, Christelle Vincent-Fabert
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Activating mutations of MYD88 (MYD88L265P being the far most frequent) are found in most cases of Waldenström macroglobulinemia (WM) as well as in various aggressive B-cell lymphoma entities with features of plasma cell (PC) differentiation, such as
Externí odkaz:
https://doaj.org/article/6ae2c3b7bfc345f6b7a93a374d068805
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
At the crossroad between biology and mathematical modeling, computational systems biology can contribute to a mechanistic understanding of high-level biological phenomenon. But as knowledge accumulates, the size and complexity of mathematical models
Externí odkaz:
https://doaj.org/article/95da829ca53b483285f0ca1a6cc14733
Autor:
Darely Y. Gutiérrez-Reyna, Alejandra Cedillo-Baños, Linda A. Kempis-Calanis, Oscar Ramírez-Pliego, Lisa Bargier, Denis Puthier, Jose D. Abad-Flores, Morgane Thomas-Chollier, Denis Thieffry, Alejandra Medina-Rivera, Salvatore Spicuglia, Maria A. Santana
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neonates are highly susceptible to intracellular pathogens, leading to high morbidity and mortality rates. CD8+ T lymphocytes are responsible for the elimination of infected cells. Understanding the response of these cells to normal and high stimulat
Externí odkaz:
https://doaj.org/article/8c177a28a4f942e9a298502304fb2cdd
Autor:
Stefanie Schöne, Marcel Jurk, Mahdi Bagherpoor Helabad, Iris Dror, Isabelle Lebars, Bruno Kieffer, Petra Imhof, Remo Rohs, Martin Vingron, Morgane Thomas-Chollier, Sebastiaan H. Meijsing
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
To modulate gene expression, the glucocorticoid receptor binds to response elements (RE) that vary in sequence. Here, the authors show that RE sequences can modulate glucocorticoid receptor structure and activity, which might provide regulatory speci
Externí odkaz:
https://doaj.org/article/2a1ad04ab2d040d4bcff1e24f2469042
Autor:
Kilian Mazaleyrat, Cherif Badja, Natacha Broucqsault, Raphaël Chevalier, Camille Laberthonnière, Camille Dion, Lyla Baldasseroni, Claire El-Yazidi, Morgane Thomas, Richard Bachelier, Alexandre Altié, Karine Nguyen, Nicolas Lévy, Jérôme D. Robin, Frédérique Magdinier
Publikováno v:
Cells, Vol 9, Iss 6, p 1531 (2020)
Induced pluripotent stem cells (iPSCs) obtained by reprogramming primary somatic cells have revolutionized the fields of cell biology and disease modeling. However, the number protocols for generating mature muscle fibers with sarcolemmal organizatio
Externí odkaz:
https://doaj.org/article/8d061bb2ffea436e998913b85cd1c2af
Autor:
Stefanie Schöne, Melissa Bothe, Edda Einfeldt, Marina Borschiwer, Philipp Benner, Martin Vingron, Morgane Thomas-Chollier, Sebastiaan H Meijsing
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007793 (2018)
The binding of transcription factors to short recognition sequences plays a pivotal role in controlling the expression of genes. The sequence and shape characteristics of binding sites influence DNA binding specificity and have also been implicated i
Externí odkaz:
https://doaj.org/article/22536acae04444baaecd4a10d51fffb2
Autor:
Elodie Thierion, Johan Le Men, Samuel Collombet, Céline Hernandez, Fanny Coulpier, Patrick Torbey, Morgane Thomas-Chollier, Daan Noordermeer, Patrick Charnay, Pascale Gilardi-Hebenstreit
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006903 (2017)
Developmental genes can harbour multiple transcriptional enhancers that act simultaneously or in succession to achieve robust and precise spatiotemporal expression. However, the mechanisms underlying cooperation between cis-acting elements are poorly
Externí odkaz:
https://doaj.org/article/d3a4bbc3b0594c56bff0e9b49f7f0575
Autor:
Bruno Hudry, Morgane Thomas-Chollier, Yael Volovik, Marilyne Duffraisse, Amélie Dard, Dale Frank, Ulrich Technau, Samir Merabet
Publikováno v:
eLife, Vol 3 (2014)
Despite tremendous body form diversity in nature, bilaterian animals share common sets of developmental genes that display conserved expression patterns in the embryo. Among them are the Hox genes, which define different identities along the anterior
Externí odkaz:
https://doaj.org/article/1e02995c6eee45dea1cd3479b5e5f3ea