Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Morgane Humbel"'
Autor:
Eri Katsuyama, Morgane Humbel, Abel Suarez-Fueyo, Abhigyan Satyam, Nobuya Yoshida, Vasileios C. Kyttaris, Maria G. Tsokos, George C. Tsokos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract CD38 has emerged as a potential therapeutic target for patients with systemic lupus erythematosus (SLE) but it is not known whether CD38 alters CD4+ T cell function. Using primary human T cells and CD38-sufficient and CD38-deficient Jurkat T
Externí odkaz:
https://doaj.org/article/d0cd238c69d947889a5549cbde81b514
Autor:
Alice Horisberger, Morgane Humbel, Natalia Fluder, Florence Bellanger, Craig Fenwick, Camillo Ribi, Denis Comte
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Determining disease activity in systemic lupus erythematosus (SLE) patients is challenging and limited by the lack of reliable biomarkers. Abnormally activated B cells play a key role in the pathogenesis of SLE, but their measure in clinical
Externí odkaz:
https://doaj.org/article/11ecd6cb6203472391c4dbaef91d1057
Autor:
Morgane Humbel, Florence Bellanger, Alice Horisberger, Madeleine Suffiotti, Natalia Fluder, Mariko Makhmutova, Amandine Mathias, Renaud Du Pasquier, Craig Fenwick, Camillo Ribi, Denis Comte
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology, linked to alterations in both the innate and the adaptive immune system. Due to the heterogeneity of the clinical presentation, the diagnosis of SLE remains compl
Externí odkaz:
https://doaj.org/article/a36a57ab635947f29b6aab5536eadc97
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Innate lymphoid cells (ILC) are a heterogeneous group of immune cells characterized by lymphoid morphology and cytokine profile similar to T cells but which do not express clonally distributed diverse antigen receptors. These particular cells express
Externí odkaz:
https://doaj.org/article/711067fbc63d48459a1dac143fe9a951
Autor:
Morgane Humbel, Florence Bellanger, Natalia Fluder, Alice Horisberger, Madeleine Suffiotti, Craig Fenwick, Camillo Ribi, Denis Comte
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by multiple cellular and molecular dysfunctions of the innate and adaptive immunity. Cytotoxic function of NK cells is compromised in patients with SLE. Herein, we c
Externí odkaz:
https://doaj.org/article/394bb2a7c729425f9b8e6dd85fcc8039
Autor:
Alexia Boizot, Sylvain Moser, Virginie Zimmer, Nicole Déglon, Mélanie Sipion, Sara Regio, Maria Rey, Morgane Humbel, Ludiwine Aeby, Mergim Ramosaj
Publikováno v:
Gene Therapy
Gene therapy, vol. 28, no. 1-2, pp. 75-88
Gene therapy, vol. 28, no. 1-2, pp. 75-88
Gene transfer is a widely developed technique for studying and treating genetic diseases. However, the development of therapeutic strategies is challenging, due to the cellular and functional complexity of the central nervous system (CNS), its large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0caf98d1e7ad605f836975aa1ada83fb
https://doi.org/10.1038/s41434-020-0172-6
https://doi.org/10.1038/s41434-020-0172-6
Autor:
Alice, Horisberger, Morgane, Humbel, Natalia, Fluder, Florence, Bellanger, Craig, Fenwick, Camillo, Ribi, Denis, Comte
Publikováno v:
Scientific reports. 12(1)
Determining disease activity in systemic lupus erythematosus (SLE) patients is challenging and limited by the lack of reliable biomarkers. Abnormally activated B cells play a key role in the pathogenesis of SLE, but their measure in clinical practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c7d12157aa92c1f944cc96710f9ce84
https://pubmed.ncbi.nlm.nih.gov/35654865
https://pubmed.ncbi.nlm.nih.gov/35654865
Autor:
Morgane Humbel, Florence Bellanger, Alice Horisberger, Madeleine Suffiotti, Natalia Fluder, Mariko Makhmutova, Amandine Mathias, Renaud Du Pasquier, Craig Fenwick, Camillo Ribi, Denis Comte
Publikováno v:
Frontiers in immunology, vol. 13, pp. 843059
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown etiology, linked to alterations in both the innate and the adaptive immune system. Due to the heterogeneity of the clinical presentation, the diagnosis of SLE remains compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16db8881fda274b931548534edd97e6c
https://pubmed.ncbi.nlm.nih.gov/35603218
https://pubmed.ncbi.nlm.nih.gov/35603218
Autor:
Alice Horisberger, Morgane Humbel, Natalia Fluder, Florence Bellanger, Craig Fenwick, Camillo Ribi, Denis Comte
Background Determining disease activity in systemic lupus erythematosus (SLE) patients is challenging and limited by the lack of reliable biomarkers. Analysis of the altered distribution of circulating B cells has shown promise for assessment disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eca6e06fa14c4f1cd66c70f78724fc17
https://doi.org/10.21203/rs.3.rs-1061479/v1
https://doi.org/10.21203/rs.3.rs-1061479/v1
Publikováno v:
Clinical Immunology. 204:57-63
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease characterized by a breakdown in immune tolerance leading to the development of auto-reactive lymphocytes and autoantibodies. Recent findings have provided new insight on the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5f26eb6784bcc3f66e6a0c0fbd6e41
https://doi.org/10.1016/j.clim.2018.11.001
https://doi.org/10.1016/j.clim.2018.11.001