Immune response after pig-to-human kidney xenotransplantation: a multimodal phenotyping study.

Autor: Loupy A; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France; Department of Kidney Transplantation, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France. Electronic address: alexandre.loupy@inserm.fr., Goutaudier V; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France; Department of Kidney Transplantation, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France., Giarraputo A; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France; Cardiovascular Pathology and Pathological Anatomy, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy., Mezine F; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France., Morgand E; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France., Robin B; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France., Khalil K; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Pharmacy, NYU Langone Health, New York, NY, USA., Mehta S; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Keating B; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA., Dandro A; Revivicor, Blacksburg, VA, USA., Certain A; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France., Tharaux PL; Paris Cardiovascular Research Center, PARCC, INSERM U970, Université Paris Cité, Paris, France., Narula N; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA., Tissier R; Ecole Nationale Vétérinaire d'Alfort, IMRB, After ROSC Network, Maisons-Alfort, France., Giraud S; INSERM U1313, IRMETIST, Université de Poitiers et CHU de Poitiers, Poitiers, France., Hauet T; INSERM U1313, IRMETIST, Université de Poitiers et CHU de Poitiers, Poitiers, France., Pass HI; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Cardiothoracic Surgery, NYU Grossman School of Medicine, New York, NY, USA; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Sannier A; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France; Department of Pathology, Bichat Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France., Wu M; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA., Griesemer A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Ayares D; Revivicor, Blacksburg, VA, USA., Tatapudi V; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Stern J; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Lefaucheur C; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France; Kidney Transplant Department, Saint-Louis Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France., Bruneval P; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France; Department of Pathology, Georges Pompidou European Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France., Mangiola M; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA., Montgomery RA; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.

Publikováno v: Lancet (London, England) [Lancet] 2023 Sep 30; Vol. 402 (10408), pp. 1158-1169. Date of Electronic Publication: 2023 Aug 17.

Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung cancer.

Autor: Ghiringhelli F; Platform of Transfer in Biological Oncology, Georges François Leclerc Cancer Center - UNICANCER, Dijon, France; Genomic and Immunotherapy Medical Institute, Dijon University Hospital, Dijon, France; University of Burgundy-Franche Comté, Maison de l'Université Esplanade Erasme, Dijon, France; UMR INSERM 1231, Dijon, France; Department of Medical Oncology, Georges François Leclerc Cancer Center - UNICANCER, Dijon, France., Bibeau F; Department of Pathology, Besançon University Hospital, Franche-Comté University, Besançon, France; Department of Pathology, Caen University Hospital, Normandy University, Caen, France., Greillier L; Multidisciplinary Oncology and Therapeutic Innovations Department, APHM, INSERM, CNRS, CRCM, Hôpital Nord, Aix Marseille University, Marseille, France., Fumet JD; Platform of Transfer in Biological Oncology, Georges François Leclerc Cancer Center - UNICANCER, Dijon, France; Genomic and Immunotherapy Medical Institute, Dijon University Hospital, Dijon, France; University of Burgundy-Franche Comté, Maison de l'Université Esplanade Erasme, Dijon, France; UMR INSERM 1231, Dijon, France; Department of Medical Oncology, Georges François Leclerc Cancer Center - UNICANCER, Dijon, France., Ilie A; Platform of Transfer in Biological Oncology, Georges François Leclerc Cancer Center - UNICANCER, Dijon, France., Monville F; Veracyte, Marseille, France., Laugé C; Veracyte, Marseille, France., Catteau A; Veracyte, Marseille, France., Boquet I; Veracyte, Marseille, France., Majdi A; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France; Equipe Labellisée Ligue Contre le Cancer, Paris, France; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, Paris, France., Morgand E; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France; Equipe Labellisée Ligue Contre le Cancer, Paris, France; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, Paris, France., Oulkhouir Y; Department of Thoracic Oncology, Caen University Hospital, Normandy University, Caen, France., Brandone N; Eurofins Pathologie, Bd Charles Moretti, Marseille 13014, France., Adam J; Anatomie et Cytologie Pathologiques, Hôpital Paris Saint-Joseph, INSERM, Gustave Roussy, Université Paris Saclay, Paris, France., Sbarrato T; Veracyte, Marseille, France., Kassambara A; Veracyte, Marseille, France., Fieschi J; Veracyte, Marseille, France., Garcia S; Multidisciplinary Oncology and Therapeutic Innovations Department, APHM, INSERM, CNRS, CRCM, Hôpital Nord, Aix Marseille University, Marseille, France., Lepage AL; Platform of Transfer in Biological Oncology, Georges François Leclerc Cancer Center - UNICANCER, Dijon, France; Department of Pathology, Besançon University Hospital, Franche-Comté University, Besançon, France., Tomasini P; Multidisciplinary Oncology and Therapeutic Innovations Department, APHM, INSERM, CNRS, CRCM, Hôpital Nord, Aix Marseille University, Marseille, France., Galon J; Veracyte, Marseille, France; INSERM, Laboratory of Integrative Cancer Immunology, Paris, France; Equipe Labellisée Ligue Contre le Cancer, Paris, France; Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, Paris, France. Electronic address: jerome.galon@crc.jussieu.fr.

Publikováno v: EBioMedicine [EBioMedicine] 2023 Jun; Vol. 92, pp. 104633. Date of Electronic Publication: 2023 May 25.

In Vivo Luciferin–Luciferase Reaction in Micro-Mini Pigs Using Xenogeneic Rat Bone Marrow Transplantation.

Autor: Abe, Tomoyuki^1,2 (AUTHOR), Endo, Kazuhiro¹ (AUTHOR), Hanazono, Yutaka^1,2 (AUTHOR), Kobayashi, Eiji^1,3 (AUTHOR) eijikoba@jikei.ac.jp

Publikováno v: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8609. 8p.

Evolution of Metastases in Space and Time under Immune Selection.

Autor: Angelova M; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France., Mlecnik B; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France; Inovarion, Paris, France., Vasaturo A; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France., Bindea G; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France., Fredriksen T; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France., Lafontaine L; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France., Buttard B; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France., Morgand E; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France., Bruni D; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France., Jouret-Mourin A; Institut Roi Albert II, Department of Medical Oncology Cliniques universitaires St-Luc and Institut de Recherche Clinique et Experimentale (Pole MIRO), Université Catholique de Louvain, 1348 Brussels, Belgium., Hubert C; Institut Roi Albert II, Department of Medical Oncology Cliniques universitaires St-Luc and Institut de Recherche Clinique et Experimentale (Pole MIRO), Université Catholique de Louvain, 1348 Brussels, Belgium., Kartheuser A; Institut Roi Albert II, Department of Medical Oncology Cliniques universitaires St-Luc and Institut de Recherche Clinique et Experimentale (Pole MIRO), Université Catholique de Louvain, 1348 Brussels, Belgium., Humblet Y; Institut Roi Albert II, Department of Medical Oncology Cliniques universitaires St-Luc and Institut de Recherche Clinique et Experimentale (Pole MIRO), Université Catholique de Louvain, 1348 Brussels, Belgium., Ceccarelli M; Department of Science and Technology, Università degli Studi del Sannio, 82100, Benevento, Italy; BIOGEM Istituto di Ricerche Genetiche 'G. Salvatore,' I-83031 Ariano Irpino, Italy., Syed N; Biomedical Informatics Division, Sidra Medicine, Doha, Qatar., Marincola FM; Refuge Biotechnologies Inc., Menlo Park, CA 94025, USA; Office of the Chief Research Officer, Sidra Medicine, 26999 Doha, Qatar., Bedognetti D; Tumor Biology, Immunology, and Therapy Section, Sidra Medicine, 26999 Doha, Qatar., Van den Eynde M; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France; Institut Roi Albert II, Department of Medical Oncology Cliniques universitaires St-Luc and Institut de Recherche Clinique et Experimentale (Pole MIRO), Université Catholique de Louvain, 1348 Brussels, Belgium., Galon J; INSERM, Laboratory of Integrative Cancer Immunology, Sorbonne Université, Sorbonne Paris Cité, Université Paris Descartes, Université Paris Diderot, Centre de Recherche des Cordeliers, 75006 Paris, France. Electronic address: jerome.galon@crc.jussieu.fr.

Publikováno v: Cell [Cell] 2018 Oct 18; Vol. 175 (3), pp. 751-765.e16. Date of Electronic Publication: 2018 Oct 11.

Immunogram defines four cancer-immunity cycle phenotypes with distinct clonal selection patterns across solid tumors.

Autor: Hu, Ying^1,2 (AUTHOR), Sun, Huaibo³ (AUTHOR), Shi, Wei⁴ (AUTHOR), Chen, Chen^1,2 (AUTHOR), Wu, Xueying^1,2 (AUTHOR), Jiang, Yu^1,2 (AUTHOR), Zhang, Guoying^1,2 (AUTHOR), Li, Na^1,2 (AUTHOR), Song, Jin⁵ (AUTHOR), Zhang, Hao⁴ (AUTHOR), Shen, Baiyong^6,7 (AUTHOR) shenby@shsmu.edu.cn, Zeng, Hui^1,2 (AUTHOR) zenghui@ccmu.edu.cn, Zhang, Henghui^1,2,8 (AUTHOR) zhhbao@ccmu.edu.cn

Publikováno v: Journal of Translational Medicine. 1/19/2024, Vol. 22 Issue 1, p1-15. 15p.