Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Morgan S. A. Gilman"'
Autor:
Irina Shlosman, Elayne M. Fivenson, Morgan S. A. Gilman, Tyler A. Sisley, Suzanne Walker, Thomas G. Bernhardt, Andrew C. Kruse, Joseph J. Loparo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The peptidoglycan (PG) cell wall protects bacteria against osmotic lysis and determines cell shape, making this structure a key antibiotic target. Peptidoglycan is a polymer of glycan chains connected by peptide crosslinks, and its synthesis
Externí odkaz:
https://doaj.org/article/46f4aabe611d4823be2a46c4d4c0f829
Autor:
Morgan S. A. Gilman, Polina Furmanova-Hollenstein, Gabriel Pascual, Angélique B. van ‘t Wout, Johannes P. M. Langedijk, Jason S. McLellan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The respiratory syncytial virus (RSV) F glycoprotein forms a trimeric complex and mediates viral entry. Using structures of RSV F in complex with antibodies, Gilman et al. here show a breathing motion of the prefusion conformation of F, resulting in
Externí odkaz:
https://doaj.org/article/9532301d0812415caee29f9be8ded047
Autor:
Iebe Rossey, Morgan S. A. Gilman, Stephanie C. Kabeche, Koen Sedeyn, Daniel Wrapp, Masaru Kanekiyo, Man Chen, Vicente Mas, Jan Spitaels, José A. Melero, Barney S. Graham, Bert Schepens, Jason S. McLellan, Xavier Saelens
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Neutralizing antibodies for respiratory syncytial virus (RSV) can reduce disease in hospitalized children, but current options show limited efficacy. Here, the authors isolate potent single-domain antibodies from llamas that recognize the prefusion c
Externí odkaz:
https://doaj.org/article/93c63b0a60fe4bb4a99ee0b83523552a
Autor:
Iebe Rossey, Morgan S. A. Gilman, Stephanie C. Kabeche, Koen Sedeyn, Daniel Wrapp, Masaru Kanekiyo, Man Chen, Vicente Mas, Jan Spitaels, José A. Melero, Barney S. Graham, Bert Schepens, Jason S. McLellan, Xavier Saelens
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14158 (2017); Published 13 February 2017; Updated 29 November 2017. In this Article, the clinical isolate MAD/GM3_10/14 of respiratory syncytial virus (RSV) is incorrectly described as an RSV A isolate. MAD/GM
Externí odkaz:
https://doaj.org/article/3e09bc00b05a44aa9f8cf03469adf01d
Autor:
Harrison G Jones, Tina Ritschel, Gabriel Pascual, Just P J Brakenhoff, Elissa Keogh, Polina Furmanova-Hollenstein, Ellen Lanckacker, Jehangir S Wadia, Morgan S A Gilman, R Anthony Williamson, Dirk Roymans, Angélique B van 't Wout, Johannes P Langedijk, Jason S McLellan
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006935 (2018)
Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections in infants and the elderly, and yet there remains no effective treatment or vaccine. The surface of the virion is decorated with the fusion glycoprotein (
Externí odkaz:
https://doaj.org/article/934d8568511a4a31a4fe4f3f7569d4dc
Autor:
Morgan S A Gilman, Syed M Moin, Vicente Mas, Man Chen, Nita K Patel, Kari Kramer, Qing Zhu, Stephanie C Kabeche, Azad Kumar, Concepción Palomo, Tim Beaumont, Ulrich Baxa, Nancy D Ulbrandt, José A Melero, Barney S Graham, Jason S McLellan
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005035 (2015)
Prevention efforts for respiratory syncytial virus (RSV) have been advanced due to the recent isolation and characterization of antibodies that specifically recognize the prefusion conformation of the RSV fusion (F) glycoprotein. These potently neutr
Externí odkaz:
https://doaj.org/article/6bbdfb9a96f440d5a4a0d09486df35de