Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Morgan L. Kleiber"'
Autor:
Benjamin I. Laufer, Katarzyna Mantha, Morgan L. Kleiber, Eric J. Diehl, Sean M. F. Addison, Shiva M. Singh
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 4, Pp 977-992 (2013)
SUMMARY Fetal alcohol spectrum disorders (FASDs) are characterized by life-long changes in gene expression, neurodevelopment and behavior. What mechanisms initiate and maintain these changes are not known, but current research suggests a role for alc
Externí odkaz:
https://doaj.org/article/ea3c1e1389bf471ab79b7d9c3d0323b2
Autor:
Aditi Thakur, Morgan L. Kleiber, Elizabeth P. Hayden, Shiva M. Singh, Yuliya Kotelnikova, Andrew R. Daoust
Publikováno v:
Child Psychiatry & Human Development. 54:672-682
Shorter telomeres mark cellular aging and are linked to chronic stress exposure as well as negative physical and psychological outcomes. However, it is unclear whether telomere length mediates associations between early stress exposure and later exte
Autor:
Morgan L Kleiber, Eric J Diehl, Benjamin I Laufer, Katarzyna eMantha, Aniruddho eChokroborty Hoque, Bonnie eAlberry, Shiva M Singh
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
There is abundant evidence that prenatal alcohol exposure leads to a range of behavioural and cognitive impairments, categorized under the term fetal alcohol spectrum disorders (FASDs). These disorders are pervasive in Western cultures and represent
Externí odkaz:
https://doaj.org/article/31cb84da9bf549718856b9212a684557
Autor:
Javiera Uribe Fenner, Andrea B. Moffitt, William M. Brandler, Kiely N. James, Danny Antaki, Melissa Gymrek, Sara A. Wirth, An Nguyen, Jing Gu, Camila Araújo Bernardino Garcia, Renee D. George, Renatta Knox, Xiaoxu Yang, Martin W. Breuss, Joseph G. Gleeson, Jennifer McEvoy-Venneri, Orrin Devinsky, Zihua Wang, Evan Sticca, Amaia Hervás, Madhusudan Gujral, Jonathan Sebat, Maria Cárcel Pérez, Martha Cristina Cancino Botello, Maria Arranz, Damir Musaev, Morgan L. Kleiber, Oanh Hong, Ileena Mitra, Laurel L. Ball
Publikováno v:
Nature medicine, vol 26, iss 1
Nature medicine
Nature medicine
De novo mutations arising on the paternal chromosome make the largest known contribution to autism risk, and correlate with paternal age at the time of conception. The recurrence risk for autism spectrum disorders is substantial, leading many familie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e035c1c0aa752b35dc7b8fa6d1c66303
https://escholarship.org/uc/item/33p6091g
https://escholarship.org/uc/item/33p6091g
Autor:
Silvina Guijarro, Daniel J. Turner, Isabel Rueda, Keith K. Vaux, Amaia Hervás, Caroline M. Nievergelt, Stephen W. Scherer, Roser Corominas, Denis Bisson, William M. Brandler, Yan Yang, Michelle S. Maile, Shih C. Tang, Claudio Toma, Christina Corsello, Shirley Tan, Jonathan Sebat, Prateek Tandon, Joe Whitney, Maria J. Arranz, Timothy Pang, Amalio Telenti, Zhuozhi Wang, Danny Antaki, Alysson R. Muotri, J. Craig Venter, Karen Pierce, Eoghan D. Harrington, Eric Courchesne, Karen Messer, Madhusudan Gujral, Sissel Juul, Boyko Kakaradov, Oanh Hong, Morgan L. Kleiber, Bru Cormand, Timothy R. Chapman, Stephen F. Kingsmore, Gaganjot Kaur, Lilia M. Iakoucheva, Joseph G. Gleeson, Bhooma Thiruvahindrapuram
Publikováno v:
Science (New York, N.Y.), vol 360, iss 6386
Brandler, WM; Antaki, D; Gujral, M; Kleiber, ML; Whitney, J; Maile, MS; et al.(2018). Paternally inherited cis-regulatory structural variants are associated with autism. SCIENCE, 360(6386), 327-330. doi: 10.1126/science.aan2261. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/5vm6k60d
Science
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Brandler, WM; Antaki, D; Gujral, M; Kleiber, ML; Whitney, J; Maile, MS; et al.(2018). Paternally inherited cis-regulatory structural variants are associated with autism. SCIENCE, 360(6386), 327-330. doi: 10.1126/science.aan2261. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/5vm6k60d
Science
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Inherited variation contributes to autismAbout one-quarter of genetic variants that are associated with autism spectrum disorder (ASD) are due to de novo mutations in protein-coding genes. Brandleret al.wanted to determine whether changes in noncodin
Autor:
Jonathan Sebat, An Nguyen, Renatta Knox, Orrin Devinsky, Martin W. Breuss, Renee D. George, Jennifer McEvoy-Venneri, Joseph G. Gleeson, Kiely N. James, Garcia Cab, Damir Musaev, Danny Antaki, Evan Sticca, Melissa Gymrek, Morgan L. Kleiber, Oanh Hong, Laurel L. Ball
SummaryDe novo genetic mutations represent a major contributor to pediatric disease, including autism spectrum disorders (ASD), congenital heart disease, and muscular dystrophies1,2, but there are currently no methods to prevent or predict them. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5c24a3ce44738f329fcf954b99ce8f
https://doi.org/10.1101/208165
https://doi.org/10.1101/208165
Autor:
Eric Courchesne, Amaia Hervás, Jonathan Sebat, Karen Messer, Boyko Kakaradov, Karen Pierce, Shih C. Tang, Daniel J. Turner, Shirley Tan, J. Craig Venter, Oanh Hong, Caroline M. Nievergelt, Roser Corominas, Michelle S. Maile, Alysson R. Muotri, Maria J. Arranz, Timothy Pang, Amalio Telenti, Christina Corsello, Eoghan D. Harrington, Prateek Tandon, Timothy R. Chapman, Madhusudan Gujral, William M. Brandler, Bru Cormand, Sissel Juul, Morgan L. Kleiber, Stephen F. Kingsmore, Yan Yang, Lilia M. Iakoucheva, Joseph G. Gleeson, Isabel Rueda, Danny Antaki, Keith K. Vaux
The genetic architecture of autism spectrum disorder (ASD) is known to consist of contributions from gene-disrupting de novo mutations and common variants of modest effect. We hypothesize that the unexplained heritability of ASD also includes rare in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea7bedf0363522e35d85cab7cbfe133
Publikováno v:
Developmental Neuroscience. 36:499-519
The developing brain is remarkably sensitive to alcohol exposure, resulting in the wide range of cognitive and neurobehavioral characteristics categorized under the term fetal alcohol spectrum disorders (FASD). The brain is particularly susceptible t
Autor:
A. Lippa, Amanda J. Roberts, M.L. Maile, Oanh Hong, Jonathan Sebat, Timothy R. Chapman, Morgan L. Kleiber, R. Purcell
Publikováno v:
European Neuropsychopharmacology. 29:S1077
Publikováno v:
Journal of Behavioral and Brain Science. :85-99
Maternal drinking during pregnancy can result in a wide spectrum of cognitive and behavioral abnormalities termed fetal alcohol spectrum disorders (FASD). The heterogeneity observed in FASD-related phenotypes can be attributed to a number of environm