Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Morgan Knight"'
Autor:
Yifan Wu, Evan Li, Morgan Knight, Grace Adeniyi-Ipadeola, Li-Zhen Song, Alan R Burns, Ana Clara Gazzinelli-Guimaraes, Ricardo Fujiwara, Maria Elena Bottazzi, Jill E Weatherhead
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 12, p e0010050 (2021)
Ascariasis is one of the most common infections in the world and associated with significant global morbidity. Ascaris larval migration through the host's lungs is essential for larval development but leads to an exaggerated type-2 host immune respon
Externí odkaz:
https://doaj.org/article/9aacc5138edf459eba62a113517836c7
Autor:
Yifan Wu, Shuqi Du, Lynn H. Bimler, Kelsey E. Mauk, Léa Lortal, Nessim Kichik, James S. Griffiths, Radim Osicka, Lizhen Song, Katherine Polsky, Lydia Kasper, Peter Sebo, Jill Weatherhead, J. Morgan Knight, Farrah Kheradmand, Hui Zheng, Jonathan P. Richardson, Bernhard Hube, Julian R. Naglik, David B. Corry
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113240- (2023)
Summary: The fungal pathogen Candida albicans is linked to chronic brain diseases such as Alzheimer’s disease (AD), but the molecular basis of brain anti-Candida immunity remains unknown. We show that C. albicans enters the mouse brain from the blo
Externí odkaz:
https://doaj.org/article/c973f39dfee7477fac57548342be679b
Autor:
John Morgan Knight, Yifan Wu, Kelsey Mauk, Jill Weatherhead, Sara Anvari, Farrah Kheradmand, David B. Corry
Publikováno v:
Journal of Fungi, Vol 6, Iss 2, p 74 (2020)
Filamentous fungi of the Aspergillus genus and others have long been linked to the induction of type 2 immunity that underlies IgE-mediated hypersensitivity responses. This unique immune response is characterized by the production of the allergy-asso
Externí odkaz:
https://doaj.org/article/a32b4304b3994cb6b7e8a747fbc9bb81
Autor:
Hua Sun, Ashish Damania, Megan L. Mair, Eniola Otukoya, Yi-Dong Li, Katherine Polsky, Yuying Zeng, Jeremiah A. Alt, Martin J. Citardi, David B. Corry, Amber U. Luong, John Morgan Knight
Publikováno v:
Frontiers in Immunology. 13
Unified airway disease, including concurrent asthma and chronic rhinosinusitis (CRS), is a common, but poorly understood disorder with no curative treatment options. To establish a murine model of chronic unified eosinophilic airway inflammation, mic
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB189
Autor:
Hua, Sun, Ashish, Damania, Megan L, Mair, Eniola, Otukoya, Yi-Dong, Li, Katherine, Polsky, Yuying, Zeng, Jeremiah A, Alt, Martin J, Citardi, David B, Corry, Amber U, Luong, John Morgan, Knight
Publikováno v:
Frontiers in immunology. 13
Unified airway disease, including concurrent asthma and chronic rhinosinusitis (CRS), is a common, but poorly understood disorder with no curative treatment options. To establish a murine model of chronic unified eosinophilic airway inflammation, mic
Autor:
Yifan Wu, Paul Porter, Matthew C. Madison, David B. Corry, Antony Rodriguez, Farrah Kheradmand, J. Morgan Knight, Matthew J. Flick, Zhimin Zeng, Cameron T. Landers, Hui Ying Tung
Publikováno v:
J Biol Chem
Proteinases are essential drivers of allergic airway disease and innate antifungal immunity in part through their ability cleave the clotting factor fibrinogen (FBG) into fibrinogen cleavage products (FCPs) that signal through Toll-like receptor 4 (T
Autor:
Zachary W. Marshall, Hui Ying Tung, Amber U Luong, Cameron T. Landers, J. Morgan Knight, Evan Li, David B. Corry, Antony Rodriguez, Farrah Kheradmand
Publikováno v:
Annals of the American Thoracic Society. 15:S198-S204
Asthma, chronic rhinosinusitis, and related incurable allergic afflictions of the upper and lower airways are medically important because of their association with the disabling symptom of dyspnea and, at least for asthma, the potential to cause fata
Autor:
Matthew C. Madison, Dev K. Chatterjee, David B. Corry, Ed Felix, Atul Varadhachary, John S. McMurray, Melissa M. Singh, Joel M. Sederstrom, Brandon Saxton, Pietro Morlacchi, Garbo Mak, Cameron T. Landers, Pijus K. Mandal, Brian E. Gilbert, J. Morgan Knight, Evan Li
Publikováno v:
Journal of Biological Chemistry. 293:10026-10040
Asthma is a chronic inflammatory disease of the lungs and airways and one of the most burdensome of all chronic maladies. Previous studies have established that expression of experimental and human asthma requires the IL-4/IL-13/IL-4 receptor α (IL-
Autor:
Evan Li, Farrah Kheradmand, An Nguyen, J. Morgan Knight, David B. Corry, Cameron T. Landers, Hui Ying Tung
Publikováno v:
Seminars in Respiratory and Critical Care Medicine. 39:064-081
Allergic asthma is a heterogeneous disorder that defies a unanimously acceptable definition, but is generally recognized through its highly characteristic clinical expression of dyspnea and cough accompanied by clinical data that document reversible