Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Morgan Graeme Blaylock"'
Autor:
J. Graham Douglas, Garry Michael Walsh, Richard J. Brooker, Peter Joseph Benedict Helms, Morgan Graeme Blaylock, C. M. McDougall
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 39:560-568
The nose is an attractive source of airway epithelial cells, particularly in populations in which bronchoscopy may not be possible. However, substituting nasal cells for bronchial epithelial cells in the study of airway inflammation depends upon comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7237e514e4ce55144c22b63a0422cecf
https://doi.org/10.1165/rcmb.2007-0325oc
https://doi.org/10.1165/rcmb.2007-0325oc
Autor:
Garry Michael Walsh, Morgan Graeme Blaylock, J. G. Douglas, A. Lawrie, Christopher J A Duncan
Publikováno v:
European Respiratory Journal. 22:484-490
This study was carried out to investigate the relationship between induced sputum eosinophil apoptosis and clinical severity score, airway obstruction and symptom scores in patients with chronic stable asthma. Altogether, 41 chronic stable asthmatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1f9c592fd9d8a700c77301f9119cbf
https://doi.org/10.1183/09031936.03.00109803a
https://doi.org/10.1183/09031936.03.00109803a
Autor:
Daniel K. C. Lee, Owen J. Dempsey, Garry Michael Walsh, Christopher J A Duncan, A. Lawrie, Brian J. Lipworth, Morgan Graeme Blaylock, J. G. Douglas
Publikováno v:
Clinical & Experimental Allergy. 33:936-941
Summary Background Eosinophils and their secreted mediators are heavily implicated as effector cells in asthma and other allergic diseases. Comparisons were made between expression of CD45, CD45RA, CD45RB and CD45RO by eosinophils from asthmatic pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de5bed7a730f2e06984d36b401366dad
https://doi.org/10.1046/j.1365-2222.2003.01697.x
https://doi.org/10.1046/j.1365-2222.2003.01697.x
Publikováno v:
Journal of Endocrinology. 178:37-43
Anti-inflammatory therapy in asthma is reliant on corticosteroids, particularly in their inhaled form. However, steroids are rather non-specific in their actions and they also raise concerns regarding compliance and side-effect Issues. Furthermore, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c99d946a35adcdf73d786c4d7d0c8c9
https://doi.org/10.1677/joe.0.1780037
https://doi.org/10.1677/joe.0.1780037
Publikováno v:
Clinical & Experimental Allergy. 33:640-648
BACKGROUND Eosinophils are now recognized as major effector cells in allergic and asthmatic disease with a potent armoury of mediators whose release makes a major contribution to the inflammation underlying these conditions. OBJECTIVES The purpose of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8263d9faf9869f08f2a22b3d20da10ce
https://doi.org/10.1046/j.1365-2222.2003.01639.x
https://doi.org/10.1046/j.1365-2222.2003.01639.x
Publikováno v:
Clinical & Experimental Allergy. 32:1187-1192
BACKGROUND Several second-generation antihistamines have documented anti-inflammatory effects which appear independent of H1-receptor blockade. We investigated the inhibitory effect of cetirizine and its active enantiomer levocetirizine on eosinophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65b12e95246f5154161c04a35017effa
https://doi.org/10.1046/j.1365-2745.2002.01444.x
https://doi.org/10.1046/j.1365-2745.2002.01444.x
Publikováno v:
Journal of Allergy and Clinical Immunology. 108:962-969
Background: We previously demonstrated receptor-mediated apoptotic-eosinophil engulfment by human small airway epithelial cells, which may represent a potentially important mechanism in the resolution of allergic and asthmatic inflammation. Objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6604907ec02dc35e0b8c0a5c41f925
https://doi.org/10.1067/mai.2001.119414
https://doi.org/10.1067/mai.2001.119414
Autor:
N.Ranald Ferguson, Morgan Graeme Blaylock, Nigel R. Webster, Brian H Cuthbertson, Helen F. Galley
Publikováno v:
Free Radical Biology and Medicine. 25:748-752
In acute lung injury, neutrophil apoptosis may be important in regulating the inflammatory process by controlling neutrophil numbers and thus activity. Exogenous inhaled nitric oxide is now a widely used therapy in patients with acute lung injury, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb9256abeef0ff38cb21ae384f24c46
https://doi.org/10.1016/s0891-5849(98)00108-7
https://doi.org/10.1016/s0891-5849(98)00108-7
Autor:
Garry Michael Walsh, Alison M. Lawrie, Morgan Graeme Blaylock, Christopher J A Duncan, Darren W. Sexton, M. Al-Rabia
Publikováno v:
Current drug targets. Inflammation and allergy. 4(4)
The inappropriate accumulation of eosinophils and the subsequent release of their potent pro-inflammatory mediator arsenal are thought to be important contributors to the pathogenesis of asthma and other allergic diseases. It is also becoming apparen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a105742081b82b0270065ed4a390b5
https://pubmed.ncbi.nlm.nih.gov/16101525
https://pubmed.ncbi.nlm.nih.gov/16101525
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 34(10)
Summary Background We have previously demonstrated that human bronchial epithelial cells engulf apoptotic eosinophils. Objectives To compare and contrast the phagocytic capabilities of monocyte-derived macrophage and primary airway epithelial cells f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88cc205755970becb49b02947ed9d74a
https://pubmed.ncbi.nlm.nih.gov/15479265
https://pubmed.ncbi.nlm.nih.gov/15479265