Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Morgan Gallazzini"'
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113032- (2023)
Summary: Mitochondrial dysfunction is a critical process in renal epithelial cells upon kidney injury. While its implication in kidney disease progression is established, the mechanisms modulating it remain unclear. Here, we describe the role of Lipo
Externí odkaz:
https://doaj.org/article/1965e843d698442e91e0bdf7f60ba2dc
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 2067-2077.e6 (2019)
Summary: Epidermal growth factor receptor (EGFR) activation and lipocalin-2 (Lcn2) expression are frequently observed in the same pathological contexts, such as cancers or chronic kidney disease (CKD). However, the significance of this association is
Externí odkaz:
https://doaj.org/article/b06ce8c0303348fe80a31f10aed7e79f
Autor:
Khalil El Karoui, Amandine Viau, Olivier Dellis, Alessia Bagattin, Clément Nguyen, William Baron, Martine Burtin, Mélanie Broueilh, Laurence Heidet, Géraldine Mollet, Anne Druilhe, Corinne Antignac, Bertrand Knebelmann, Gérard Friedlander, Frank Bienaimé, Morgan Gallazzini, Fabiola Terzi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Proteinuria promotes chronic kidney disease progression. Karoui et al. show that proteinuria stimulates overexpression of iron transporting protein lipocalin-2 via Ca2+release-induced ER stress, which leads to tubular apoptosis, and that inhibition o
Externí odkaz:
https://doaj.org/article/84d6beb4c2bc4aa9bafacf3ebe31468b
Autor:
Margarita Kunin, Natalia I Dmitrieva, Morgan Gallazzini, Rong-Fong Shen, Guanghui Wang, Maurice B Burg, Joan D Ferraris
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12108 (2010)
Hypertonicity, such as induced by high NaCl, increases the activity of the transcription factor TonEBP/OREBP whose target genes increase osmoprotective organic osmolytes and heat shock proteins.We used mass spectrometry to analyze proteins that coimm
Externí odkaz:
https://doaj.org/article/82ec2d8ea4124b5c8781fe5e5fd5c55b
Publikováno v:
The FASEB Journal. 36
Autor:
Marion Rabant, Jean Luc Taupin, Aniela Zablocki, Tifanie Blein, Soëli Charbonnier, Dany Anglicheau, Charlotte Leclaire, Baptiste Lamarthée, Carole Burger, Julien Zuber, Fabiola Terzi, Mélanie Hardy, Lise Morin, Xavier Lebreton, Béatrice Charreau, Claire Tinel, Christophe Legendre, Renaud Snanoudj, Emilie Lebraud, Morgan Gallazzini, Simon C. Satchell
Publikováno v:
Journal of the American Society of Nephrology
Journal of the American Society of Nephrology, 2021, 32 (12), pp.3231-3251. ⟨10.1681/ASN.2021050689⟩
et al. 2021, ' CRISPR/Cas9-Engineered HLA-Deleted Glomerular Endothelial Cells as a Tool to Predict Pathogenic Non-HLA Antibodies in Kidney Transplant Recipients ', Journal of the American Society of Nephrology, vol. 32, no. 12, pp. 3231-3251 . https://doi.org/10.1681/ASN.2021050689
J Am Soc Nephrol
Journal of the American Society of Nephrology, 2021, 32 (12), pp.3231-3251. ⟨10.1681/ASN.2021050689⟩
et al. 2021, ' CRISPR/Cas9-Engineered HLA-Deleted Glomerular Endothelial Cells as a Tool to Predict Pathogenic Non-HLA Antibodies in Kidney Transplant Recipients ', Journal of the American Society of Nephrology, vol. 32, no. 12, pp. 3231-3251 . https://doi.org/10.1681/ASN.2021050689
J Am Soc Nephrol
International audience; Background After kidney transplantation, donor-specific antibodies against human leukocyte antigen donor-specific antibodies (HLA-DSAs) drive antibody-mediated rejection (ABMR) and are associated with poor transplant outcomes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c08aa7396eb4fc1ab9a4479a0df4d54
https://hal.science/hal-03661055
https://hal.science/hal-03661055
Autor:
Lucie Yammine, Mohamad Zaidan, Marco Pontoglio, Serena Germano, Marie-Claire Gubler, Gérard Friedlander, Serge Garbay, Morgan Gallazzini, Clément Nguyen, Jitao David Zhang, Thomas Blanc, Laura Badi, Pauline Barre, Fabiola Terzi, Martine Burtin, Florence Vasseur
Publikováno v:
JCI Insight
The loss of functional nephrons after kidney injury triggers the compensatory growth of the remaining ones to allow functional adaptation. However, in some cases, these compensatory events activate signaling pathways that lead to pathological alterat
Autor:
Nicolas Pallet, Morgan Gallazzini
Publikováno v:
Biology of the Cell. 110:205-216
Chronic kidney disease (CKD) affects millions of persons worldwide and constitutes a major public health problem. Therefore, understanding the molecular basis of CKD is a key challenge for the development of preventive and therapeutic strategies. A m
Autor:
Christophe Legendre, Clément Nguyen, Xavier Lebreton, Lucile Amrouche, Clémentine Rabaté, Morgan Gallazzini, Geoffroy Desbuissons, Pauline Barre, Marion Rabant, Virginia Sauvaget, Fabiola Terzi, Dany Anglicheau, Aurélien Benon
Publikováno v:
Journal of the American Society of Nephrology. 28:479-493
AKI leads to tubular injury and interstitial inflammation that must be controlled to avoid the development of fibrosis. We hypothesized that microRNAs are involved in the regulation of the balance between lesion formation and adaptive repair. We foun
Autor:
Pierre Laurent-Puig, Nicolas Bouvier, Morgan Gallazzini, Pierre-Louis Tharaux, Philippe Beaune, Marion Rabant, Guo-Fu Hu, Eric Chevet, Iadh Mami, Shuping Li, Eric Thervet, Nicolas Pallet, Khalil El Karoui
Publikováno v:
Journal of the American Society of Nephrology. 27:863-876
Endoplasmic reticulum (ER) stress is involved in the pathophysiology of kidney disease and aging, but the molecular bases underlying the biologic outcomes on the evolution of renal disease remain mostly unknown. Angiogenin (ANG) is a ribonuclease tha