Výsledky vyhledávání - "Morgan E. Collins"

Akademický článek

Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity

Autor: Rida Iftikhar, Harrison M. Penrose, Angelle N. King, Joshua S. Samudre, Morgan E. Collins, Alifiani B. Hartono, Sean B. Lee, Frank Lau, Melody Baddoo, Erik F. Flemington, Susan E. Crawford, Suzana D. Savkovic

Publikováno v: Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)

Abstract Obesity is a worldwide epidemic associated with increased risk and progression of colon cancer. Here, we aimed to determine the role of adipose triglyceride lipase (ATGL), responsible for intracellular lipid droplet (LD) utilization, in obes

Externí odkaz: https://doaj.org/article/dad0fa3c4c914a0ebba7e45d5f2c7f93

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Akademický článek

Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy

Autor: Harrison M. Penrose, Rida Iftikhar, Morgan E. Collins, Eman Toraih, Emmanuelle Ruiz, Nathan Ungerleider, Hani Nakhoul, Erik F. Flemington, Emad Kandil, Shamita B. Shah, Suzana D. Savkovic

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Abstract The heterogeneous pathobiology underlying Ulcerative Colitis (UC) is not fully understood. Using publicly available transcriptomes from adult UC patients, we identified the immune cell landscape, molecular pathways, and differentially expres

Externí odkaz: https://doaj.org/article/e760a94f0fe148a6a82d2a1f02490469

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Akademický článek

Correction: Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity

Publikováno v: Oncogenesis, Vol 11, Iss 1, Pp 1-1 (2022)

Externí odkaz: https://doaj.org/article/df3e440f84514614aa5dd372b8cc26ab

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Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity

Autor: Morgan E. Collins, Frank H. Lau, Erik F. Flemington, Suzana D. Savkovic, Harrison M. Penrose, Rida Iftikhar, Alifiani B. Hartono, Sean Bong Lee, Angelle N. King, Susan E. Crawford, Melody Baddoo, Joshua S. Samudre

Publikováno v: Oncogenesis
Oncogenesis, Vol 10, Iss 11, Pp 1-10 (2021)

Obesity is a worldwide epidemic associated with increased risk and progression of colon cancer. Here, we aimed to determine the role of adipose triglyceride lipase (ATGL), responsible for intracellular lipid droplet (LD) utilization, in obesity-drive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5cf30400829f3e73b4e210e3cd35d2
https://pubmed.ncbi.nlm.nih.gov/35292620

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Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy

Autor: Emmanuelle Ruiz, Hani Nakhoul, Morgan E. Collins, Shamita B. Shah, Harrison M. Penrose, Eman A. Toraih, Emad Kandil, Erik F. Flemington, Rida Iftikhar, Nathan Ungerleider, Suzana D. Savkovic

Publikováno v: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

The heterogeneous pathobiology underlying Ulcerative Colitis (UC) is not fully understood. Using publicly available transcriptomes from adult UC patients, we identified the immune cell landscape, molecular pathways, and differentially expressed genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506749b68d6e2c32b7838f54083cbbc8
http://europepmc.org/articles/PMC8079702

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DIFFERENTIALLY EXPRESSED GENE SIGNATURES OF ULCERATIVE COLITIS DETERMINE NOVEL REGULATORS AND PREDICT RESPONSE TO BIOLOGIC THERAPY

Autor: Emmanuelle Ruiz, Rida Iftikhar, Morgan E. Collins, Suzana D. Savkovic, Emad Kandil, Harrison M. Penrose, Eman A. Toraih

Publikováno v: Gastroenterology. 160:S38-S39

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2451093a4542dbca65a281e288ab212d
https://doi.org/10.1053/j.gastro.2021.01.111

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Fr151 COLON CANCER STEM CELL GROWTH AND TRANSCRIPTIONAL REMODELING IS MEDIATED BY AN INCREASED LIPID DROPLET-ASSOCIATED ADIPOSE TRIGLYCERIDE LIPASE (ATGL)

Autor: Suzana D. Savkovic, Rida Iftikhar, Harrison M. Penrose, Morgan E. Collins

Publikováno v: Gastroenterology. 160:S-239

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b4188b136e45d008184984511e02033
https://doi.org/10.1016/s0016-5085(21)01314-7

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46 OBESITY-PROMOTED COLON CANCER PROGRESSION IS FACILITATED BY LIPID DROPLET-ASSOCIATED ADIPOSE TRIGLYCERIDE LIPASE (ATGL)

Autor: Suzana D. Savkovic, Harrison M. Penrose, Rida Iftikhar, Morgan E. Collins

Publikováno v: Gastroenterology. 160:S-13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf518e9298bd51937ef6bfc82c2acbcf
https://doi.org/10.1016/s0016-5085(21)00783-6

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Casein Kinase I Isoform Hrr25 Is a Negative Regulator of Haa1 in the Weak Acid Stress Response Pathway in Saccharomyces cerevisiae

Autor: Joshua J. Black, Morgan E. Collins, Zhengchang Liu

Publikováno v: Applied and Environmental Microbiology. 83

Haa1 is a transcription factor that adapts Saccharomyces cerevisiae cells to weak organic acid stresses by activating the expression of various genes. Many of these genes encode membrane proteins, such as TPO2 and YRO2 . How Haa1 is activated by weak

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cab898a7317ce742418ae08ef44b18
https://doi.org/10.1128/aem.00672-17

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