Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Morgan Diolaiti"'
Autor:
Felix Y. Feng, Eric J. Small, Alan Ashworth, Tomasz M. Beer, Jack Youngren, Charles Ryan, Christopher J. Lord, Karen Knudsen, Scott Tomlins, George Thomas, Colin Pritchard, Morgan Diolaiti, Rajdeep Das, Matti Annala, Kevin Beja, Jacob Schwartzman, Eric Lu, Won Kim, Rahul Aggarwal, Paul Lloyd, Adam Foye, Vishal Kothari, Alexander W. Wyatt, Joshi J. Alumkal, David Quigley
Supplementary Table S1: Patient 1 reversion alleles. Supplementary Table 2: DNA read identifiers supporting reversion alleles. Supplementary Table S3: Gene targets of the SeqCap library used for cfDNA sequencing. Supplementary Figure S1: Frequent los
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f124c125d5ff779f4d55630cba3cda5
https://doi.org/10.1158/2159-8290.22532236
https://doi.org/10.1158/2159-8290.22532236
Autor:
Seock-Ah Im, Kyung-Hun Lee, Ahrum Min, Daewon Lee, Tae Yong Kim, Han Suk Ryu, Jiwon Koh, Gi-Jeong Cheon, Yoon-Jung Shin, Yujin Kim, Hyeong-Gon Moon, Wonshik Han, Han-Byoel Lee, Morgan Diolaiti, David Quigley, Alan Ashworth, Nariya Cho
Publikováno v:
Cancer Research. 82:PD15-08
Background PARP inhibitors have proven efficacy in breast cancer patients with germline BRCA1 or BRCA2 mutations (gBRCAmt) but also have potential to be effective in cancers with defects in homologous recombination (HR) DNA repair. Moreover, synergy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b03a92270821483865cdf6815d462a2a
https://doi.org/10.1158/1538-7445.sabcs21-pd15-08
https://doi.org/10.1158/1538-7445.sabcs21-pd15-08
Autor:
Daniel V. Santi, Denis R. Beckford-Vera, William D. Figg, Ryan Nguyen, Cody J. Peer, Alan Ashworth, Morgan Diolaiti, Raushan T. Kurmasheva, Peter J. Houghton, Gary W. Ashley, Shaun D. Fontaine
PARP inhibitors are approved for treatment of cancers with BRCA1 or BRCA2 defects. In this study, we prepared and characterized a very long-acting PARP inhibitor. Synthesis of a macromolecular prodrug of talazoparib (TLZ) was achieved by covalent con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31785d6bf07d9a537aace6bcbfbcf928
https://doi.org/10.1158/0008-5472.c.6512476.v1
https://doi.org/10.1158/0008-5472.c.6512476.v1
Autor:
Daniel V. Santi, Denis R. Beckford-Vera, William D. Figg, Ryan Nguyen, Cody J. Peer, Alan Ashworth, Morgan Diolaiti, Raushan T. Kurmasheva, Peter J. Houghton, Gary W. Ashley, Shaun D. Fontaine
Supplemental methods, data, and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fe37868b2849c55845d001d71dbc61
https://doi.org/10.1158/0008-5472.22426861
https://doi.org/10.1158/0008-5472.22426861
Autor:
Stefan Gahbauer, Galen J. Correy, Marion Schuller, Matteo P. Ferla, Yagmur Umay Doruk, Moira Rachman, Taiasean Wu, Morgan Diolaiti, Siyi Wang, R. Jeffrey Neitz, Daren Fearon, Dmytro Radchenko, Yurii Moroz, John J. Irwin, Adam R. Renslo, Jenny C. Taylor, Jason E. Gestwicki, Frank von Delft, Alan Ashworth, Ivan Ahel, Brian K. Shoichet, James S. Fraser
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 120, iss 2
The nonstructural protein 3 (NSP3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains a conserved macrodomain enzyme (Mac1) that is critical for pathogenesis and lethality. While small molecule inhibitors of Mac1 have great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991faf3ec537a19849a09bb30d7edb38
https://pubmed.ncbi.nlm.nih.gov/36598939
https://pubmed.ncbi.nlm.nih.gov/36598939
Autor:
Stefan, Gahbauer, Galen J, Correy, Marion, Schuller, Matteo P, Ferla, Yagmur Umay, Doruk, Moira, Rachman, Taiasean, Wu, Morgan, Diolaiti, Siyi, Wang, R Jeffrey, Neitz, Daren, Fearon, Dmytro, Radchenko, Yurii, Moroz, John J, Irwin, Adam R, Renslo, Jenny C, Taylor, Jason E, Gestwicki, Frank, von Delft, Alan, Ashworth, Ivan, Ahel, Brian K, Shoichet, James S, Fraser
Publikováno v:
bioRxiv : the preprint server for biology.
The nonstructural protein 3 (NSP3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains a conserved macrodomain enzyme (Mac1) that is critical for pathogenesis and lethality. While small molecule inhibitors of Mac1 have great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0d1f125f48c87de315a09265cca538b
https://pubmed.ncbi.nlm.nih.gov/35794891
https://pubmed.ncbi.nlm.nih.gov/35794891