Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Morgan A. Giese"'
Autor:
Morgan A. Giese, Gayathri Ramakrishnan, Laura H. Steenberge, Jerome X. Dovan, John-Demian Sauer, Anna Huttenlocher
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 9 (2024)
Externí odkaz:
https://doaj.org/article/f6f87228e9c14960b503ae17bf4d53e9
Autor:
Benjamin G. Korte, Morgan A. Giese, Gayathri Ramakrishnan, Stella Ma, David Bennin, Julie Rindy, Colin N. Dewey, Anna Huttenlocher
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neutrophils in the tumor microenvironment exhibit altered functions. However, the changes in neutrophil behavior during tumor initiation remain unclear. Here we used Translating Ribosomal Affinity Purification (TRAP) and RNA sequencing to identify ne
Externí odkaz:
https://doaj.org/article/ede9b05827824af7968f97b36a214a20
Autor:
Taylor J Schoen, Dante G Calise, Jin Woo Bok, Morgan A Giese, Chibueze D Nwagwu, Robert Zarnowski, David Andes, Anna Huttenlocher, Nancy P Keller
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011152 (2023)
Hyphal growth is essential for host colonization during Aspergillus infection. The transcription factor ZfpA regulates A. fumigatus hyphal development including branching, septation, and cell wall composition. However, how ZfpA affects fungal growth
Externí odkaz:
https://doaj.org/article/54b4ec096f514a7f8c91391b1326d8c7
Publikováno v:
The Astrophysical Journal, Vol 952, Iss 1, p 50 (2023)
Presented here are NOEMA interferometric observations of the neighboring hot cores W3(H _2 O) and W3(OH). The presence of two star-forming cores at different evolutionary stages within the same parent cloud presents a unique opportunity to study how
Externí odkaz:
https://doaj.org/article/8f81e052d03a40ccbfac5f73e77e30a0
Autor:
Emily C. Britt, Jorgo Lika, Morgan A. Giese, Taylor J. Schoen, Gretchen L. Seim, Zhengping Huang, Pui Y. Lee, Anna Huttenlocher, Jing Fan
Publikováno v:
Nature Metabolism. 4:389-403
Neutrophils are cells at the frontline of innate immunity that can quickly activate effector functions to eliminate pathogens upon stimulation. However, little is known about the metabolic adaptations that power these functions. Here we show rapid me
Autor:
Laurel E. Hind, Anna Huttenlocher, Morgan A Giese, Taylor J. Schoen, David J. Beebe, Nancy P. Keller
Publikováno v:
Cellular and Molecular Bioengineering. 14:133-145
Neutrophils act as first responders during an infection, following signals from the pathogen as well as other host cells to migrate from blood vessels to the site of infection. This tightly regulated process is critical for pathogen clearance and, in
Autor:
Isaac M. Barber-Axthelm, Christopher W. Peterson, Kevin G. Haworth, Anne-Sophie Kuhlmann, Hans-Peter Kiem, Christina Ironside, Morgan A. Giese
Publikováno v:
Molecular Therapy. 27:164-177
Broadly neutralizing antibodies (bNAbs) are among the most promising strategies to achieve long-term control of HIV-1 in the absence of combination antiretroviral therapy. Passive administration of such antibodies in patients efficiently decreases HI
Autor:
Emily C, Britt, Jorgo, Lika, Morgan A, Giese, Taylor J, Schoen, Gretchen L, Seim, Zhengping, Huang, Pui Y, Lee, Anna, Huttenlocher, Jing, Fan
Publikováno v:
Nature metabolism. 4(3)
Neutrophils are cells at the frontline of innate immunity that can quickly activate effector functions to eliminate pathogens upon stimulation. However, little is known about the metabolic adaptations that power these functions. Here we show rapid me
Publikováno v:
Blood
Neutrophils act as the body’s first line of defense against infection and respond to diverse inflammatory cues, including cancer. Neutrophils display plasticity, with the ability to adapt their function in different inflammatory contexts. In the tu
Autor:
Morgan A. Giese, Mark Enstrom, Lauren E Schefter, Zachary K. Norgaard, Hans-Peter Kiem, Jennifer E. Adair, Yan-Yi Chan, Stefan Radtke, Kevin G. Haworth
Publikováno v:
Science translational medicine. 9(414)
Hematopoietic reconstitution after bone marrow transplantation is thought to be driven by committed and multipotent progenitor cells followed by long-term engrafting hematopoietic stem cells (HSCs). Here, we observed a population of early-engrafting