Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Morgan A. Alford"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Pseudomonas aeruginosa and Staphylococcus aureus are often comorbid human pathogens, isolated from expectorated sputum of cystic fibrosis patients and chronically infected wounds. Prior studies revealed a competitive advantage of P. aerugino
Externí odkaz:
https://doaj.org/article/235809aaf0224cf2b9c9c6d6a0f984af
Autor:
Melanie Dostert, Corrie R. Belanger, Lucas Pedraz, Morgan A. Alford, Travis M. Blimkie, Reza F. Falsafi, Manjeet Bains, Bhavjinder Kaur Dhillon, Cara H. Haney, Amy H. Lee, Robert E. W. Hancock
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Biofilms are the most common cause of bacterial infections in humans and notoriously hard to treat due to their ability to withstand antibiotics and host immune defenses. To overcome the current lack of effective antibiofilm therapies and guide futur
Externí odkaz:
https://doaj.org/article/79fbddb4e63145be85fa13077821cf0a
Autor:
Felix L. Santana, Karel Estrada, Morgan A. Alford, Bing C. Wu, Melanie Dostert, Lucas Pedraz, Noushin Akhoundsadegh, Pavneet Kalsi, Evan F. Haney, Suzana K. Straus, Gerardo Corzo, Robert E. W. Hancock
Publikováno v:
Antibiotics, Vol 11, Iss 11, p 1603 (2022)
Host defense peptides (HDPs) represent an alternative way to address the emergence of antibiotic resistance. Crocodylians are interesting species for the study of these molecules because of their potent immune system, which confers high resistance to
Externí odkaz:
https://doaj.org/article/d2e8b5659058444793f86ae59e3ca87f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Pseudomonas aeruginosa is a metabolically versatile opportunistic pathogen capable of infecting distinct niches of the human body, including skin wounds and the lungs of cystic fibrosis patients. Eradication of P. aeruginosa infection is becoming inc
Externí odkaz:
https://doaj.org/article/7397e7cc89b943838fd63f54fa8489a9
Autor:
Morgan A. Alford, Ka-Yee G. Choi, Michael J. Trimble, Hamid Masoudi, Pavneet Kalsi, Daniel Pletzer, Robert E. W. Hancock
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The very common condition of sinusitis is characterized by persistent inflammation of the nasal cavity, which contributes to chronic rhinosinusitis and morbidity of cystic fibrosis patients. Colonization by opportunistic pathogens such as Staphylococ
Externí odkaz:
https://doaj.org/article/c077c08ea282412f9f57bf8b7e035707
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates. While their antibacterial activity toward bacterial cells was the original focus for research, their ability to modulate immune and inflammatory processes has em
Externí odkaz:
https://doaj.org/article/c4910838c9ed4ec2b1cd10f4d0436409
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Pseudomonas aeruginosa is an opportunistic pathogen that is a major cause of nosocomial and chronic infections contributing to morbidity and mortality in cystic fibrosis patients. One of the reasons for its success as a pathogen is its ability to ada
Externí odkaz:
https://doaj.org/article/787f31d3f63d4d6aa76e7505056a6d9b
Autor:
Morgan A Alford, James A Karlowsky, Heather J Adam, Melanie R Baxter, John Schellenberg, Alyssa R Golden, Irene Martin, Walter Demczuk, Michael R Mulvey, George G Zhanel
Publikováno v:
Journal of Antimicrobial Chemotherapy. 78:i8-i16
Objectives To assess the antimicrobial susceptibility of 14 138 invasive Streptococcus pneumoniae isolates collected in Canada from 2011 to 2020. Methods Antimicrobial susceptibility testing was performed using the CLSI M07 broth microdilution refere
Autor:
Josefine Eilsø Nielsen, Morgan Ashley Alford, Deborah Bow Yue Yung, Natalia Molchanova, John A. Fortkort, Jennifer S. Lin, Gill Diamond, Robert E. W. Hancock, Håvard Jenssen, Daniel Pletzer, Reidar Lund, Annelise E. Barron
Publikováno v:
ACS Infectious Diseases. 8:533-545
Publikováno v:
Nature Reviews Microbiology. 19:786-797
Host defence peptides (HDPs) are integral components of innate immunity across all living organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells (referred to as antimicrobial peptides), and exhibit antibiofilm (r