Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Morgan A Alford"'
Autor:
Lauren V Wilkinson, Morgan A Alford, Shannon R Coleman, Bing C Wu, Amy H Y Lee, Travis M Blimkie, Manjeet Bains, Reza Falsafi, Daniel Pletzer, Robert E W Hancock
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250977 (2021)
Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen that causes considerable human morbidity and mortality, particularly in nosocomial infections and individuals with cystic fibrosis. P. aeruginosa can adapt to surface growth by undergoing
Externí odkaz:
https://doaj.org/article/ae510231c40c4d9ebd4abbcf89af58d8
Autor:
Morgan A Alford, James A Karlowsky, Heather J Adam, Melanie R Baxter, John Schellenberg, Alyssa R Golden, Irene Martin, Walter Demczuk, Michael R Mulvey, George G Zhanel
Publikováno v:
Journal of Antimicrobial Chemotherapy. 78:i8-i16
Objectives To assess the antimicrobial susceptibility of 14 138 invasive Streptococcus pneumoniae isolates collected in Canada from 2011 to 2020. Methods Antimicrobial susceptibility testing was performed using the CLSI M07 broth microdilution refere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8f99f6db82e24c55589f181daa6630
https://doi.org/10.1093/jac/dkad065
https://doi.org/10.1093/jac/dkad065
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates. While their antibacterial activity toward bacterial cells was the original focus for research, their ability to modulate immune and inflammatory processes has em
Externí odkaz:
https://doaj.org/article/c4910838c9ed4ec2b1cd10f4d0436409
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Pseudomonas aeruginosa is an opportunistic pathogen that is a major cause of nosocomial and chronic infections contributing to morbidity and mortality in cystic fibrosis patients. One of the reasons for its success as a pathogen is its ability to ada
Externí odkaz:
https://doaj.org/article/787f31d3f63d4d6aa76e7505056a6d9b
Autor:
Josefine Eilsø Nielsen, Morgan Ashley Alford, Deborah Bow Yue Yung, Natalia Molchanova, John A. Fortkort, Jennifer S. Lin, Gill Diamond, Robert E. W. Hancock, Håvard Jenssen, Daniel Pletzer, Reidar Lund, Annelise E. Barron
Publikováno v:
ACS Infectious Diseases. 8:533-545
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbaa5cb960c0f08b480842265620d6b5
https://doi.org/10.1021/acsinfecdis.1c00536
https://doi.org/10.1021/acsinfecdis.1c00536
Autor:
Felix L. Santana, Karel Estrada, Morgan A. Alford, Bing C. Wu, Melanie Dostert, Lucas Pedraz, Noushin Akhoundsadegh, Pavneet Kalsi, Evan F. Haney, Suzana K. Straus, Gerardo Corzo, Robert E. W. Hancock
Publikováno v:
Antibiotics; Volume 11; Issue 11; Pages: 1603
Host defense peptides (HDPs) represent an alternative way to address the emergence of antibiotic resistance. Crocodylians are interesting species for the study of these molecules because of their potent immune system, which confers high resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f8d98e0b6b94cda012a2f809865073
Autor:
Melanie Dostert, Corrie R. Belanger, Lucas Pedraz, Morgan A. Alford, Travis M. Blimkie, Reza F. Falsafi, Manjeet Bains, Bhavjinder Kaur Dhillon, Cara H. Haney, Amy H. Lee, Robert E. W. Hancock
Publikováno v:
Frontiers in Microbiology. 13
Biofilms are the most common cause of bacterial infections in humans and notoriously hard to treat due to their ability to withstand antibiotics and host immune defenses. To overcome the current lack of effective antibiofilm therapies and guide futur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4578ba4a529f818bf2bc552e566c58b
https://doi.org/10.3389/fmicb.2022.1021021
https://doi.org/10.3389/fmicb.2022.1021021
Publikováno v:
Nature Reviews Microbiology. 19:786-797
Host defence peptides (HDPs) are integral components of innate immunity across all living organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells (referred to as antimicrobial peptides), and exhibit antibiofilm (r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::064b1e4b6787dd07b3dc9e2b3dd264ce
https://doi.org/10.1038/s41579-021-00585-w
https://doi.org/10.1038/s41579-021-00585-w
Publikováno v:
Scientific Reports. 12
Pseudomonas aeruginosa and Staphylococcus aureus are often comorbid human pathogens, isolated from expectorated sputum of cystic fibrosis patients and chronically infected wounds. Prior studies revealed a competitive advantage of P. aeruginosa over S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2084aa4070585b12a8f579d7ce6f80e8
https://doi.org/10.1038/s41598-022-12650-2
https://doi.org/10.1038/s41598-022-12650-2
Autor:
Robert E. W. Hancock, Noushin Akhoundsadegh, Morgan A. Alford, Hashem Etayash, Matthew Drayton, Suzana K. Straus
Publikováno v:
Journal of medicinal chemistry. 64(22)
Effective anti-infective therapies are required to offset the rise in antibiotic resistance. A novel vancomycin-innate defense regulator conjugate (V-IDR1018) was constructed with multimodal functionality, including bacterial killing, biofilm eradica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2c577e50c26a5de40b073e822174d1
https://pubmed.ncbi.nlm.nih.gov/35048687
https://pubmed.ncbi.nlm.nih.gov/35048687