Zobrazeno 1 - 10
of 1 070
pro vyhledávání: '"Morgan, Gj"'
Publikováno v:
Blood and Lymphatic Cancer: Targets and Therapy, Vol 2014, Iss default, Pp 107-119 (2014)
Eileen M Boyle,1,2 Brian A Walker,1 Christopher P Wardell,1 Xavier Leleu,2 Faith E Davies,1 Gareth J Morgan1 1Centre for Myeloma Research, Institute of Cancer Research, Sutton, Surrey, UK; 2Service des Maladies du Sang, Hôpital Claude Huriez, Centre
Externí odkaz:
https://doaj.org/article/c558238f6afb459aac117e4ae0fcf9a3
Autor:
Cook, G, Royle, K-L, Pawlyn, C, Hockaday, A, Shah, V, Kaiser, MF, Brown, SR, Gregory, WM, Child, JA, Davies, FE, Morgan, GJ, Cairns, DA, Jackson, GH
Publikováno v:
The Lancet. Haematology
Summary Background Tolerability of treatments for multiple myeloma can depend on the characteristics of the patient being treated. We aimed to develop and validate a risk profile, using routinely collected data, that could predict overall survival in
Autor:
Boyle, EM, Ashby, C, Tytarenko, R, Deshpande, S, Wang, Y, Sawyer, J, Tian, E, Johnson, S, Rutherford, MW, Wardell, CP, Bauer, MA, Thanendrarajan, S, Schinke, C, Zangari, M, van Rhee, F, Wang, H, Rosenthal, A, Hoering, A, Flynt, E, Thakurta, A, Dumontet, C, Facon, T, Cairns, DA, Jackson, GH, Barlogie, B, Davies, FE, Morgan, GJ, Walker, BA
Purpose: Copy number changes and translocations have been studied extensively in many datasets with long term follow-up. The impact of mutations remains debated given the short time to follow-up of most datasets. Methods: we performed targeted panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::7a857d6e27bb4ad0fcb9116b9fbf8f85
https://eprints.whiterose.ac.uk/156311/1/221937_3_merged_1579720789.pdf
https://eprints.whiterose.ac.uk/156311/1/221937_3_merged_1579720789.pdf
Autor:
McInnes, IB, Puig, L, Gottlieb, AB, Ritchlin, CT, Song, M, You, Y, Kafka, S, Morgan, GJ, Rahman, P, Kavanaugh, A, PSUMMIT 1 Study Grp, PSUMMIT 2 Study Grp
Publikováno v:
JOURNAL OF RHEUMATOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Objective. Evaluate enthesitis, physical function, and health-related quality of life (HRQOL) among patients with psoriatic arthritis (PsA) who are naive to anti-tumor necrosis factor agents. Methods. In PSUMMIT 1 and 2, patients with PsA were random
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::54d79b0fd7ae130efebfec305ba98b7c
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2388
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2388
Autor:
Jackson, GH, Davies, FE, Pawlyn, C, Cairns, DA, Striha, A, Collett, C, Hockaday, A, Jones, JR, Kishore, B, Garg, M, Williams, CD, Karunanithi, K, Lindsay, J, Jenner, MW, Cook, G, Russell, NH, Kaiser, MF, Drayson, MT, Owen, RG, Gregory, WM, Morgan, GJ, UK NCRI Haemato-oncology Clinical Studies Group
BACKGROUND: Patients with multiple myeloma treated with lenalidomide maintenance therapy have improved progression-free survival, primarily following autologous stem-cell transplantation. A beneficial effect of lenalidomide maintenance therapy on ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::5ba626b460de311f4bf4538fcef58dba
https://eprints.whiterose.ac.uk/140642/1/1-s2.0-S1470204518306879-main.pdf
https://eprints.whiterose.ac.uk/140642/1/1-s2.0-S1470204518306879-main.pdf
Autor:
Shah, V, Johnson, DC, Sherborne, AL, Ellis, S, Aldridge, FM, Howard-Reeves, J, Begum, F, Price, A, Kendall, J, Chiecchio, L, Savola, S, Jenner, MW, Drayson, MT, Owen, RG, Gregory, WM, Morgan, GJ, Davies, FE, Houlston, RS, Cook, G, Cairns, DA, Jackson, G, Kaiser, MF
Multiple myeloma (MM) is a genetically heterogeneous cancer of bone marrow plasma cells with variable outcome. To assess the prognostic relevance of clonal heterogeneity of TP53 copy number, we profiled tumors from 1777 newly diagnosed Myeloma XI tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cdeb30b742c6612e95008b7ecaeb7e15
https://europepmc.org/articles/PMC6533595/
https://europepmc.org/articles/PMC6533595/
Autor:
Went, M, Sud, A, Försti, A, Halvarsson, BM, Weinhold, N, Kimber, S, van Duin, M, Thorleifsson, G, Holroyd, A, Johnson, DC, Li, N, Orlando, G, Law, PJ, Ali, M, Chen, B, Mitchell, JS, Gudbjartsson, DF, Kuiper, R, Stephens, OW, Bertsch, U, Broderick, P, Campo, C, Bandapalli, OR, Einsele, H, Gregory, WA, Gullberg, U, Hillengass, J, Hoffmann, P, Jackson, GH, Jöckel, KH, Johnsson, E, Kristinsson, SY, Mellqvist, UH, Nahi, H, Easton, D, Pharoah, P, Dunning, A, Peto, J, Canzian, F, Swerdlow, A, Eeles, RA, Kote-Jarai, ZS, Muir, K, Pashayan, N, Nickel, J, Nöthen, MM, Rafnar, T, Ross, FM, da Silva Filho, MI, Thomsen, H, Turesson, I, Vangsted, A, Andersen, NF, Waage, A, Walker, BA, Wihlborg, AK, Broyl, A, Davies, FE, Thorsteinsdottir, U, Langer, C, Hansson, M, Goldschmidt, H, Kaiser, M, Sonneveld, P, Stefansson, K, Morgan, GJ, Hemminki, K, Nilsson, B, Houlston, RS, Henderson, BE, Haiman, CA, Benlloch, S, Schumacher, FR, Olama, AAA, Berndt, SI, Conti, DV, Wiklund, F, Chanock, S, Stevens, VL, Tangen, CM, The PRACTICAL Consortium
© 2018, The Author(s). Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1131::f7734f9e27f34106bbe3f4a96df7e407
https://lirias.kuleuven.be/handle/123456789/633372
https://lirias.kuleuven.be/handle/123456789/633372
Autor:
Johnson, DC, Lenive, O, Mitchell, J, Jackson, G, Owen, R, Drayson, M, Cook, G, Jones, JR, Pawlyn, C, Davies, FE, Walker, BA, Wardell, C, Gregory, WM, Cairns, D, Morgan, GJ, Houlston, RS, Kaiser, MF
Recent studies suggest that the evolutionary history of a cancer is important in forecasting clinical outlook. To gain insight into the clonal dynamics of multiple myeloma (MM) and its possible influence on patient outcome we analysed whole exome seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ccf49e0c1a02a2f4a5521a09d86453df
https://eprints.whiterose.ac.uk/121045/1/BLOOD-2016-750612v3-Kaiser.pdf
https://eprints.whiterose.ac.uk/121045/1/BLOOD-2016-750612v3-Kaiser.pdf
Autor:
Shah, V, Sherborne, AL, Walker, BA, Johnson, DC, Boyle, EM, Ellis, S, Begum, DB, Proszek, PZ, Jones, JR, Pawlyn, C, Savola, S, Jenner, MW, Drayson, MT, Owen, RG, Houlston, RS, Cairns, DA, Gregory, WM, Cook, G, Davies, F, Jackson, GH, Morgan, GJ, Kaiser, MF
Robust establishment of survival in multiple myeloma (MM) and its relationship to recurrent genetic aberrations is required as outcomes are variable despite apparent similar staging. We assayed copy number alterations (CNA) and translocations in 1036
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::85ee3ae844525eae55a5c49d73e065df
https://eprints.whiterose.ac.uk/117302/16/leu2017179a.pdf
https://eprints.whiterose.ac.uk/117302/16/leu2017179a.pdf
Autor:
Palumbo A, Rajkumar SV, Dimopoulos MA, Richardson PG, San Miguel J, Barlogie B, Harousseau J, Zonder JA, Zangari M, Attal M, Belch A, Knop S, JoshuaD, Sezer O, Ludwig H, Vesole D, Bladé J, Kyle R, Westin J, Weber D, Bringhen S, Niesvizky R, Waage A, von Lilienfeld Toal M, Lonial S, Morgan GJ, Orlowski RZ, Shimizu K, Anderson KC, Boccadoro M, Durie BG, Sonneveld P, Hussein MA, International Myeloma Working Group, CAVO, MICHELE
Publikováno v:
Leukemia, 22(2), 414-423. Nature Publishing Group
The incidence of venous thromboembolism (VTE) is more than 1 per thousand annually in the general population and increases further in cancer patients. The risk of VTE is higher in multiple myeloma (MM) patients who receive thalidomide or lenalidomide