Discovery of treatment for nerve agents targeting a new metabolic pathway.

Autor: Glaros T; Research and Technology Directorate, BioSciences Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Building E3150, Aberdeen Proving Ground, Gunpowder, MD, 21010, USA. tglaros@lanl.gov.; BioSciences Division, B11 Bioenergy and Biome Sciences, Los Alamos National Laboratory, SM30, Mailstop E529, PO Box 1663, Los Alamos, NM, 87545, USA. tglaros@lanl.gov., Dhummakupt ES; Research and Technology Directorate, BioSciences Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Building E3150, Aberdeen Proving Ground, Gunpowder, MD, 21010, USA., Rizzo GM; Excet, Inc., 6225 Brandon Ave, Suite 360, Springfield, VA, 22150, USA., McBride E; Research and Technology Directorate, BioSciences Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Building E3150, Aberdeen Proving Ground, Gunpowder, MD, 21010, USA.; National Academies of Sciences, Engineering, and Medicine, NRC Research Associateship Programs, 500 Fifth Street, NW, Washington, DC, 20001, USA., Carmany DO; Excet, Inc., 6225 Brandon Ave, Suite 360, Springfield, VA, 22150, USA., Wright LKM; Research and Technology Directorate, Toxicology and Obscurants Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Aberdeen Proving Ground, Gunpowder, MD, 21010, USA., Forster JS; Research and Technology Directorate, Toxicology and Obscurants Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Aberdeen Proving Ground, Gunpowder, MD, 21010, USA., Renner JA; Research and Technology Directorate, Toxicology and Obscurants Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Aberdeen Proving Ground, Gunpowder, MD, 21010, USA., Moretz RW; Research and Technology Directorate, Toxicology and Obscurants Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Aberdeen Proving Ground, Gunpowder, MD, 21010, USA., Dorsey R; Research and Technology Directorate, Toxicology and Obscurants Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Aberdeen Proving Ground, Gunpowder, MD, 21010, USA., Marten MR; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County (UMBC), Engineering Building, Baltimore, MD, USA., Huso W; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County (UMBC), Engineering Building, Baltimore, MD, USA., Doan A; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County (UMBC), Engineering Building, Baltimore, MD, USA., Dorsey CD; Kirk U.S. Army Health Clinic, 6455 Machine Rd., Aberdeen Proving Ground, Gunpowder, MD, 21005, USA., Phillips C; Research and Technology Directorate, Toxicology and Obscurants Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Aberdeen Proving Ground, Gunpowder, MD, 21010, USA., Benton B; Research and Technology Directorate, Toxicology and Obscurants Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Aberdeen Proving Ground, Gunpowder, MD, 21010, USA., Mach PM; Research and Technology Directorate, BioSciences Division, Combat Capabilities Development Command (CCDC) Chemical Biological Center, 5183 Blackhawk Rd., Building E3150, Aberdeen Proving Ground, Gunpowder, MD, 21010, USA. phillip.m.mach.civ@mail.mil.

Publikováno v: Archives of toxicology [Arch Toxicol] 2020 Sep; Vol. 94 (9), pp. 3249-3264. Date of Electronic Publication: 2020 Jul 27.