Matrix Metalloproteinase 2 and 9 Enzymatic Activities are Selectively Increased in the Myocardium of Chronic Chagas Disease Cardiomyopathy Patients: Role of TIMPs

Autor: Baron, Monique Andrade, Ferreira, Ludmila Rodrigues Pinto, Teixeira, Priscila Camillo, Moretti, Ana Iochabel Soares, Moretti, Soares, Santos, Ronaldo Honorato Barros, Frade, Amanda Farage, Kuramoto, Andréia, Debbas, Victor, Benvenuti, Luiz Alberto, Gaiotto, Fabio Antônio, Bacal, Fernando, Pomerantzeff, Pablo, Chevillard, Christophe, Kalil, Jorge, Cunha-Neto, Edecio

Publikováno v: Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Frontiers, 2022, 12, ⟨10.3389/fcimb.2022.836242⟩

Chronic Chagas disease (CCC) is an inflammatory dilated cardiomyopathy with a worse prognosis compared to other cardiomyopathies. We show the expression and activity of Matrix Metalloproteinases (MMP) and of their inhibitors TIMP (tissue inhibitor of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027df4182f79436c0ae4299d3e617675
https://doi.org/10.3389/fcimb.2022.836242