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pro vyhledávání: '"Moreno Papetti"'
Autor:
Tanveer S. Batth, Moreno Papetti, Anamarija Pfeiffer, Maxim A.X. Tollenaere, Chiara Francavilla, Jesper V. Olsen
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2784-2796 (2018)
Summary: Despite its low cellular abundance, phosphotyrosine (pTyr) regulates numerous cell signaling pathways in health and disease. We applied comprehensive phosphoproteomics to unravel differential regulators of receptor tyrosine kinase (RTK)-init
Externí odkaz:
https://doaj.org/article/f690d33ca66c4ee0aed10d6c43b99a3d
Autor:
Jesper V. Olsen, Tanveer S. Batth, Chiara Francavilla, Anamarija Pfeiffer, Moreno Papetti, Maxim A. X. Tollenaere
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2784-2796 (2018)
Cell Reports
Batth, T S, Papetti, M, Pfeiffer, A, Tollenaere, M A X, Francavilla, C & Olsen, J V 2018, ' Large-Scale Phosphoproteomics Reveals Shp-2 Phosphatase-Dependent Regulators of Pdgf Receptor Signaling ', Cell Reports, vol. 22, no. 10, pp. 2601-2614 . https://doi.org/10.1016/j.celrep.2018.02.038
Batth, T S, Papetti, M, Pfeiffer, A, Tollenaere, M A X, Francavilla, C & Olsen, J V 2018, ' Large-Scale Phosphoproteomics Reveals Shp-2 Phosphatase-Dependent Regulators of Pdgf Receptor Signaling ', Cell Reports, vol. 22, no. 10, pp. 2784-2796 . https://doi.org/10.1016/j.celrep.2018.02.038
Cell Reports
Batth, T S, Papetti, M, Pfeiffer, A, Tollenaere, M A X, Francavilla, C & Olsen, J V 2018, ' Large-Scale Phosphoproteomics Reveals Shp-2 Phosphatase-Dependent Regulators of Pdgf Receptor Signaling ', Cell Reports, vol. 22, no. 10, pp. 2601-2614 . https://doi.org/10.1016/j.celrep.2018.02.038
Batth, T S, Papetti, M, Pfeiffer, A, Tollenaere, M A X, Francavilla, C & Olsen, J V 2018, ' Large-Scale Phosphoproteomics Reveals Shp-2 Phosphatase-Dependent Regulators of Pdgf Receptor Signaling ', Cell Reports, vol. 22, no. 10, pp. 2784-2796 . https://doi.org/10.1016/j.celrep.2018.02.038
Summary: Despite its low cellular abundance, phosphotyrosine (pTyr) regulates numerous cell signaling pathways in health and disease. We applied comprehensive phosphoproteomics to unravel differential regulators of receptor tyrosine kinase (RTK)-init
Autor:
Giuseppe Cazzamali, Blagoy Blagoev, Jón Otti Sigurdsson, Jesper V. Olsen, Chiara Francavilla, Anna-Kathrine Pedersen, Kristoffer T.G. Rigbolt, Gopal Karemore, Moreno Papetti
Publikováno v:
Francavilla, C, Papetti, M, Rigbolt, K T G, Pedersen, A-K, Sigurdsson, J O, Cazzamali, G, Karemore, G, Blagoev, B & Olsen, J V 2016, ' Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking ', Nature Structural and Molecular Biology, vol. 23, no. 6, pp. 608–618 . https://doi.org/10.1038/nsmb.3218
Francavilla, C, Papetti, M, Rigbolt, K T G, Pedersen, A-K, Sigurdsson, J O, Cazzamali, G, Karemore, G, Blagoev, B & Olsen, J V 2016, ' Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking ', Nature Structural and Molecular Biology, vol. 23, pp. 608-618 . https://doi.org/10.1038/nsmb.3218
Nature Structural & Molecular Biology
Francavilla, C, Papetti, M, Rigbolt, K T G, Pedersen, A-K, Sigurdsson, J O, Cazzamali, G, Karemore, G, Blagoev, B & Olsen, J V 2016, ' Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking ', Nature Structural and Molecular Biology, vol. 23, no. 6, pp. 608-18 . https://doi.org/10.1038/nsmb.3218
Francavilla, C, Papetti, M, Rigbolt, K T G, Pedersen, A-K, Sigurdsson, J O, Cazzamali, G, Karemore, G, Blagoev, B & Olsen, J V 2016, ' Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking ', Nature Structural and Molecular Biology, vol. 23, pp. 608-618 . https://doi.org/10.1038/nsmb.3218
Nature Structural & Molecular Biology
Francavilla, C, Papetti, M, Rigbolt, K T G, Pedersen, A-K, Sigurdsson, J O, Cazzamali, G, Karemore, G, Blagoev, B & Olsen, J V 2016, ' Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking ', Nature Structural and Molecular Biology, vol. 23, no. 6, pp. 608-18 . https://doi.org/10.1038/nsmb.3218
A fascinating conundrum in cell signaling is how stimulation of the same receptor tyrosine kinase with distinct ligands generates specific outcomes. To decipher the functional selectivity of EGF and TGF-α, which induce epidermal growth factor recept