CYP2D6 Activity Is Correlated with Changes in Plasma Concentrations of Taurocholic Acid during Pregnancy and Postpartum in CYP2D6 Extensive Metabolizers.

Autor: Czuba LC; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Malhotra K; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Enthoven L; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Fay EE; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Moreni SL; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Mao J; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Shi Y; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Huang W; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Totah RA; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Isoherranen N; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington., Hebert MF; Department of Pharmaceutics, School of Pharmacy (L.C.C., W.H., N.I.), Department of Pharmacy, School of Pharmacy (K.M., L.E., M.F.H.), Department of Obstetrics and Gynecology, School of Medicine (E.E.F., S.L.M., J.M., M.F.H.), and Department of Medicinal Chemistry, School of Pharmacy (Y.S., R.A.T.), University of Washington, Seattle, Washington mhebert@uw.edu.

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2023 Nov; Vol. 51 (11), pp. 1474-1482. Date of Electronic Publication: 2023 Aug 07.

Impact of Pregnancy and Vitamin A Supplementation on CYP2D6 Activity.

Autor: Amaeze OU; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA., Czuba LC; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA., Yadav AS; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA., Fay EE; Department of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, Washington, USA., LaFrance J; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA., Shum S; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA., Moreni SL; Department of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, Washington, USA., Mao J; Department of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, Washington, USA., Huang W; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA., Isoherranen N; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA.; Milo Gibaldi Endowed Chair of Pharmaceutics, Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington, USA., Hebert MF; Department of Obstetrics and Gynecology, School of Medicine, University of Washington, Seattle, Washington, USA.; Department of Pharmacy, School of Pharmacy, University of Washington, Seattle, Washington, USA.

Publikováno v: Journal of clinical pharmacology [J Clin Pharmacol] 2023 Mar; Vol. 63 (3), pp. 363-372. Date of Electronic Publication: 2022 Nov 15.

Loop Electrosurgical Excisional Procedure (LEEP) Done for Discrepancy: Does the Time from HGSIL Affect Pathologic Grade of CIN in LEEP Specimen?

Autor: Moreni SL; Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195-6460, USA., Mitchell CM, Garcia RL, Eckert LO

Publikováno v: Obstetrics and gynecology international [Obstet Gynecol Int] 2010; Vol. 2010, pp. 743097. Date of Electronic Publication: 2010 Jun 29.