Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Mordechai Aboud"'
Autor:
Meital Shukrun, Azhar Jabareen, Ammar Abou-Kandil, Rachel Chamias, Mordechai Aboud, Mahmoud Huleihel
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89390 (2014)
BRCA1 is a multifunctional tumor suppressor, whose expression is activated by the estrogen (E2)-liganded ERα receptor and regulated by certain recruited transcriptional co-activators. Interference with BRCA1 expression and/or functions leads to high
Externí odkaz:
https://doaj.org/article/e6f75c93007349e0a7c19d4b5562ea37
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29934 (2012)
We have previously shown that TPA activates HTLV-1 LTR in Jurkat T-cells by inducing the binding of Sp1-p53 complex to the Sp1 site residing within the Ets responsive region 1 (ERR-1) of the LTR and that this activation is inhibited by PKCalpha and P
Externí odkaz:
https://doaj.org/article/7407d222ffdb451b82c5c6a30091512a
Publikováno v:
Cell Cycle. 10:3337-3345
Adult T-cell leukemia (ATL) is caused by HTLV-I. The viral Tax oncoprotein plays a central role in initiating the process to ATL. However, after infection HTLV-1 enters into latency, during which virus gene expression is very low, so that the level o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::012edb660de95782e1f272cbf7c845a9
https://doi.org/10.4161/cc.10.19.17620
https://doi.org/10.4161/cc.10.19.17620
Autor:
Shraga Segal, Mordechai Aboud, T. Yermiahu, Daniel Benharroch, Jacob Gopas, David B. Geffen, Isebrand Prinsloo
Publikováno v:
European Journal of Haematology. 55:178-183
The oncogenes c-myc and c-ras are known to elicit a cooperative tumorigenicity. In this study we investigated their role in the pathogenesis of Hodgkin's disease. The expression of these oncogenes was determined in Hodgkin's disease patients by avidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1cdfcf31ac50256a81772b52f6c222d
https://doi.org/10.1111/j.1600-0609.1995.tb00247.x
https://doi.org/10.1111/j.1600-0609.1995.tb00247.x
Publikováno v:
Journal of Molecular Medicine. 86:799-814
Nuclear factor kappa B (NF-kappaB) factors regulate a wide range of physiological and oncogenic processes. Normally, these factors are transiently activated by specific external signals which induce their dissociation from inhibitors of kappaB (Ikapp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444a2c75832310e41dd3830912fda4b9
https://doi.org/10.1007/s00109-008-0335-1
https://doi.org/10.1007/s00109-008-0335-1
Publikováno v:
International Journal of Cancer. 122:305-316
In this study we investigated the effect of Tax on nucleotide excision repair (NER) in human T-cell lines by using the host cell repair analysis of UVC-irradiated reporter plasmid. This analysis revealed a p53-dpendent NER activity in wild type (w.t.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41d0910a9d4bcc9ca12e8e62fcdb4a62
https://doi.org/10.1002/ijc.23091
https://doi.org/10.1002/ijc.23091
Autor:
Lilach Gohari, Min Li-Weber, Mahmoud Huleihel, Mordechai Aboud, Inbal Azran-Shaish, Yana Schavinsky-Khrapunsky, Yulia Tabakin-Fix, Rachel Chamias
Publikováno v:
Current Cancer Therapy Reviews. 2:101-113
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13524602548d8ef2d8e933af811ca490
https://doi.org/10.2174/157339406776872843
https://doi.org/10.2174/157339406776872843
Publikováno v:
Oncogene. 24:4521-4530
The oncogenic potential of HTLV-1 Tax protein is partially ascribed to its capacity to activate NF-kappaB. The current view is that Tax acts first in the cytoplasm to dissociate NF-kappaB factors from the IkappaB proteins and enable their nuclear tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce410ba4f7b13263bddda9d07124de37
https://doi.org/10.1038/sj.onc.1208645
https://doi.org/10.1038/sj.onc.1208645
Publikováno v:
Biochemical and Biophysical Research Communications. 304:696-700
The p21 W A F - 1 promoter contains binding sites for a number of transcription factors which mediate its activation by a variety of external signals. Moreover, it has been reported that the transcription factors involvedin p21 W A F - 1 activation b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3cf79efce2caf00bb51f6b07baaeb1
https://doi.org/10.1016/s0006-291x(03)00650-8
https://doi.org/10.1016/s0006-291x(03)00650-8
Autor:
Zahi Ben-Aroya, Mordechai Hallak, Marina Wolfson, Elena Zelin, Elena Butovsky, Martin Löchelt, Rolf M. Flügel, Igal Kedar, Andrea Grunspan, Mordechai Aboud, Amram Torgeman, Etta Livneh
Publikováno v:
Experimental Cell Research. 271:169-179
HTLV-I is etiologically implicated with tropical spastic paraparesis/HTLV-I associated myelopathy, adult T-cell leukemia and certain other diseases. However, after infection the virus enters into a dormant state, whereas the characteristics of the HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb37c736561285b1ebbe76be21c9d00c
https://doi.org/10.1006/excr.2001.5363
https://doi.org/10.1006/excr.2001.5363