Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Moran Sun"'
Autor:
Moran Sun, Minghua Yuan, Yingying Kang, Jinling Qin, Yixin Zhang, Yongtao Duan, Longfei Wang, Yongfang Yao
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 339-354 (2022)
α-Fluorinated chalcones were prepared and evaluated for their cell growth inhibitory properties against six human cancer cell lines. The most potent chalcone 4c demonstrated excellent selective toxicity against cancer cells versus normal human cells
Externí odkaz:
https://doaj.org/article/5c4dc708b2784957a21603ccbdb49539
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
A library of new heteroaromatic ring-linked chalcone analogs were designed and synthesized of these, compound 7m with α-CH3 substitution and bearing a benzofuran ring, displaying the most potent activity, with IC50 values of 0.07–0.183 µM against
Externí odkaz:
https://doaj.org/article/14feabf116f24afb8a804711e97a959e
Publikováno v:
ARKIVOC, Vol 2016, Iss 4, Pp 172-183 (2016)
Externí odkaz:
https://doaj.org/article/e0a67413e8ba4e83880b772f6e20648e
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 21:150-170
In recent decades, much attention has been given to cyclopropyl scaffolds, which commonly exist in natural products and synthetic organic molecules. Clinical drug molecules with cyclopropyl rings are an area of focus in therapeutic research due to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354f7870fffd52aafd657873ae40cbdd
https://doi.org/10.2174/1389557520666200729161150
https://doi.org/10.2174/1389557520666200729161150
Autor:
Yingying Kang, Yuanyuan Pei, Jinling Qin, Yixin Zhang, Yongtao Duan, Hua Yang, Yongfang Yao, Moran Sun
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b904c552e5abdc124af6d2e31b02d7b3
https://doi.org/10.2139/ssrn.4276226
https://doi.org/10.2139/ssrn.4276226
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c60496fbb838af298201a036d2ddc263
https://doi.org/10.2139/ssrn.4229456
https://doi.org/10.2139/ssrn.4229456
Autor:
Minghua Yuan, Jingtian Su, Yixin Zhang, Jinling Qin, Hua Yang, Yongtao Duan, Yongfang Yao, Moran Sun
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 83:129166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9ed41a09f2bd15f2edc26df37bcab88
https://doi.org/10.1016/j.bmcl.2023.129166
https://doi.org/10.1016/j.bmcl.2023.129166
Publikováno v:
Drug discovery today. 27(8)
Retinopathy of prematurity is a noticeable retinal abnormality causing common blindness in children. An uncontrolled retinal vasculature in retinopathy of prematurity inflicts vision loss in numerous children despite the accessibility to a wide range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc23c479ef9aab18078675f0f5a068b
https://pubmed.ncbi.nlm.nih.gov/35561966
https://pubmed.ncbi.nlm.nih.gov/35561966
Autor:
Moran Sun, Jinling Qin, Yingying Kang, Yixin Zhang, Mengyu Ba, Hua Yang, Yongtao Duan, Yongfang Yao
Publikováno v:
Bioorganic chemistry. 120
Multi-target drugs design has become an active research field because of their advantages in cancer treatment. In present study, HDAC inhibitors pharmacophore and 2-methoxyestradiol(2ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c190d760fdf89c8f649ca47d6a62b748
https://pubmed.ncbi.nlm.nih.gov/35078046
https://pubmed.ncbi.nlm.nih.gov/35078046
Autor:
Jinling Qin, Hongliang Li, Xuan Wang, Yixin Zhang, Yongtao Duan, Yongfang Yao, Hua Yang, Moran Sun
Publikováno v:
European Journal of Medicinal Chemistry. 243:114738
In an effort to discover anticancer agents with simultaneous effects on tubulin and angiogenesis, we designed and synthesized two series of piperlongumie (PL) derivatives by replacing of phenyl group with a variety of benzoheterocycle (series II) or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e03f0d2e78500d8afddedfb8706ff3
https://doi.org/10.1016/j.ejmech.2022.114738
https://doi.org/10.1016/j.ejmech.2022.114738