Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Moran Rathaus"'
Autor:
Moran Rathaus, Loziana Azem, Rinat Livne, Sophie Ron, Idit Ron, Rotem Hadar, Gilat Efroni, Amnon Amir, Tzipi Braun, Yael Haberman, Amir Tirosh
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 101985- (2024)
Objective: Excessive consumption of added sugars has been linked to the rise in obesity and associated metabolic abnormalities. Non-nutritive sweeteners (NNSs) offer a potential solution to reduce sugar intake, yet their metabolic safety remains deba
Externí odkaz:
https://doaj.org/article/966702a3adb845ca832827acdbcbefa4
Autor:
Idit Ron, Reut Kassif Lerner, Moran Rathaus, Rinat Livne, Sophie Ron, Ehud Barhod, Rina Hemi, Amit Tirosh, Tzipora Strauss, Keren Ofir, Ido Goldstein, Itai M. Pessach, Amir Tirosh
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
During pregnancy, fetal glucose production is suppressed, with rapid activation immediately postpartum. Fatty acid–binding protein 4 (FABP4) was recently demonstrated as a regulator of hepatic glucose production and systemic metabolism in animal mo
Externí odkaz:
https://doaj.org/article/9128e759e9e1420eb809744ca1ac8e25
Autor:
Victoria Peshti, Alexey Obolensky, Liat Nahum, Yariv Kanfi, Moran Rathaus, Maytal Avraham, Simon Tinman, Fredrick W Alt, Eyal Banin, Haim Y Cohen
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176371 (2017)
The NAD+-dependent SIRT6 deacetylase was shown to be a major regulator of lifespan and healthspan. Mice deficient for SIRT6 develop a premature aging phenotype and metabolic defects, and die before four weeks of age. Thus, the effect of SIRT6 deficie
Externí odkaz:
https://doaj.org/article/5828971d35ea408f88520d5c4681d65c
Autor:
Noah Gruber, Ehud Barhod, Orit Pinhas-Hamiel, Sharon Sheinvald, Amir Tirosh, Moran Rathaus, Rina Hemi, Idit Ron, Amit Tirosh, Rinat Livne
Publikováno v:
Diabetologia. 65:366-374
Fatty acid-binding protein 4 (FABP4) is an adipokine with a key regulatory role in glucose and lipid metabolism. We prospectively evaluated the role of FABP4 in the pathophysiology of diabetic ketoacidosis (DKA) in new-onset type 1 diabetes. Clinical
Publikováno v:
Diabetes. 71
Accumulating evidence link sugar-containing foods and beverages to adverse health outcomes. Non-Caloric Sweeteners (NCSs) are an alternative sugar source that lead to reduction in calories, and may mitigate body weight gain and hyperglycemia, especia
Publikováno v:
Diabetes. 71
Obesity is a leading global health concern and a major risk factor for type-2 diabetes. Thus, identifying mechanisms linking obesity to insulin resistance is of great importance. Chronic low-grade inflammation of the adipose tissue (AT) observed in o
Autor:
Tzipora Strauss, Sophie Ron, Rinat Livne, Keren Ofir, Idit Ron, Moran Rathaus, Ido Goldstein, Amir Tirosh, Reut Kassif Lerner, Amit Tirosh, Itai M. Pessach, Ehud Barhod, Rina Hemi
Publikováno v:
JCI Insight
During pregnancy, fetal glucose production is suppressed, with rapid activation immediately postpartum. Fatty acid-binding protein 4 (FABP4) was recently demonstrated as a regulator of hepatic glucose production and systemic metabolism in animal mode
Publikováno v:
Diabetes. 69
Gestational diabetes mellitus (GDM) is characterized by maternal hyperglycemia and insulin resistance that develops during pregnancy. Altered secretion of adipokines that modulate insulin action during pregnancy has been implicated in GDM pathogenesi
Autor:
Idit Ron, Ediz S. Calay, Amir Tirosh, Rinat Livne, Amit Tirosh, Sophie Ron, Moran Rathaus, Abdullah Yalcin, Yankun G. Lee, Gurol Tuncman, Gökhan S. Hotamisligil, Ana Paula Arruda, Neri Minsky
Publikováno v:
Cell Metab
Endoplasmic reticulum stress (ERS) has a pathophysiological role in obesity-associated insulin resistance. Yet, the coordinated tissue response to ERS remains unclear. Increased connexin 43 (Cx43)-mediated intercellular communication has been implica
Autor:
Ediz S. Calay, Amir Tirosh, Idit Ron, Iris Shai, Rajesh Garg, Lu Qi, Karen Inouye, Kathryn Claiborn, Michael A.D. Alcala, Gurol Tuncman, Gökhan S. Hotamisligil, Kosei Eguchi, Rinat Livne, Yoriko Heianza, Kenneth Hollander, Moran Rathaus
Publikováno v:
Science Translational Medicine. 11
The short-chain fatty acid propionate is a potent inhibitor of molds that is widely used as a food preservative and endogenously produced by gut microbiota. Although generally recognized as safe by the U.S. Food and Drug Administration, the metabolic