Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Moran G. Goren"'
Autor:
Tridib Mahata, Shahar Molshanski-Mor, Moran G. Goren, Miriam Kohen-Manor, Ido Yosef, Oren Avram, Dor Salomon, Udi Qimron
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACTBacteriophages (phages) have evolved effective methods of exploiting host-cell machinery by redirecting molecular pathways. In this study, we describe an inhibitor of bacterial growth, T5.008, encoded by the T5 phage. High-throughput sequenci
Externí odkaz:
https://doaj.org/article/59e8ea68ca6548ea8a7572d330b36e84
Publikováno v:
Cell Reports, Vol 16, Iss 11, Pp 2811-2818 (2016)
Prokaryotic adaptive immune systems are composed of clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins. These systems adapt to new threats by integrating short nucleic acids, termed spacers, into t
Externí odkaz:
https://doaj.org/article/c2129a40683a450e86436dc511af9c36
Autor:
Moran G. Goren, Yehuda Carmeli, Mitchell J. Schwaber, Inna Chmelnitsky, Vered Schechner, Shiri Navon-Venezia
Publikováno v:
Emerging Infectious Diseases, Vol 16, Iss 6, Pp 1014-1017 (2010)
Klebsiella pneumoniae carbapenemase (KPC) 3–producing Escherichia coli was isolated from a carrier of KPC-3–producing K. pneumoniae. The KPC-3 plasmid was identical in isolates of both species. The patient's gut flora contained a carbapenem-susce
Externí odkaz:
https://doaj.org/article/5a7a71d86e664e85859c746bf48348b9
Bacteria are found in ongoing conflicts with rivals and predators, which lead to an evolutionary arms race and the development of innate and adaptive immune systems. Although diverse bacterial immunity mechanisms have been recently identified, many r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73f59a83e5eed51ff3257833a30f5d0a
https://doi.org/10.1101/2023.03.28.534373
https://doi.org/10.1101/2023.03.28.534373
Many phage engineering technologies, mainly based on the CRISPR-Cas system, have been recently developed. Here we present a method to genetically engineer theEscherichia coliphages T5, T7, and P1 by adapting a technology, called pORTMAGE, developed f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d7a3d4fb174c87f5e56322572de21b
https://doi.org/10.1101/2023.03.26.534254
https://doi.org/10.1101/2023.03.26.534254
Autor:
Michael Mor, Ariel Munitz, Michal Itan, Michal Stein, Shaul Lev, Moran G. Goren, Liat Edry-Botzer, Udi Qimron, Ran Tur-Kaspa, Natalia T. Freund, Dani Cohen, Motti Gerlic, Yariv Wine, Dror Dicker, Tamar Gottesman, D. Marcoviciu, Khitam Muhsen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Despite ongoing efforts to characterize the host response toward SARS-CoV-2, a major gap in our knowledge still exists regarding the magnitude and duration of the humoral response. Analysis of the antibody response in mild versus moderate/severe pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8390c7416a8160ba21ceadfe2a4726
https://doaj.org/article/a1ba2337325c40c4bd8595bff203b6bf
https://doaj.org/article/a1ba2337325c40c4bd8595bff203b6bf
Autor:
Shahar Molshanski-Mor, Miriam Kohen-Manor, Tal Pupko, Moran G. Goren, Tridib Mahata, Dor Salomon, Udi Qimron, Oren Avram, Biswanath Jana, Ido Yosef
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Studying the interactions of bacterial viruses (phages) with their bacterial hosts may lead to better understanding of bacterial mechanisms and consequently enable better manipulation of bacterial pathogens. In this study, we characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e68305c4b85eb5e0e8869a05b55856
https://doi.org/10.1073/pnas.2026354118
https://doi.org/10.1073/pnas.2026354118
Autor:
Tamar Gottesman, Daniel Cohen, Motti Gerlic, Udi Qimron, Shuval Lev, Michael Mor, Moran G. Goren, Yariv Wine, Dana Markovitch, Liat Edry-Botzer, Miguel Stein, Ariel Munitz, Michal Itan, Ran Tur-Kaspa, Dror Dicker, Natalia T. Freund, Khitam Muhsen
Despite ongoing efforts to characterize the host response toward SARS-CoV-2, a major gap in our knowledge still exists regarding the magnitude and duration of the humoral response. We report the development of a rapid, highly specific and sensitive e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e7ed4170c7feac7c464c4f19a43548
https://doi.org/10.1101/2020.06.28.20141838
https://doi.org/10.1101/2020.06.28.20141838
Publikováno v:
Drug Resistance Updates. 30:1-6
The extensive use of antibiotics over the last century has resulted in a significant artificial selection pressure for antibiotic-resistant pathogens to evolve. Various strategies to fight these pathogens have been introduced including new antibiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085ddeffce3bf1df4dc1a981722f9ae1
https://doi.org/10.1016/j.drup.2016.11.001
https://doi.org/10.1016/j.drup.2016.11.001
Publikováno v:
Trends in Microbiology. 23:744-746
Bacteriophages, bacteria's natural enemies, may serve as potent antibacterial agents. Their specificity for certain bacterial sub-species limits their effectiveness, but allows selective targeting of bacteria. Lu and colleagues present a platform for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84729369afb84b4878815f0772848172
https://doi.org/10.1016/j.tim.2015.10.006
https://doi.org/10.1016/j.tim.2015.10.006