Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders.

Autor: Chandra G; Section on Developmental Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1830, USA., Bagh MB; Section on Developmental Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1830, USA., Peng S; Section on Developmental Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1830, USA., Saha A; Section on Developmental Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1830, USA., Sarkar C; Section on Developmental Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1830, USA., Moralle M; Section on Developmental Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1830, USA., Zhang Z; Section on Developmental Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1830, USA., Mukherjee AB; Section on Developmental Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1830, USA mukherja@exchange.nih.gov.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2015 Oct 01; Vol. 24 (19), pp. 5416-32. Date of Electronic Publication: 2015 Jul 09.

Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function.

Autor: Gorenberg, Erica L.^1,2 (AUTHOR), Massaro Tieze, Sofia^1,2 (AUTHOR), Yücel, Betül¹ (AUTHOR), Zhao, Helen R.¹ (AUTHOR), Chou, Vicky¹ (AUTHOR), Wirak, Gregory S.¹ (AUTHOR), Tomita, Susumu^1,3 (AUTHOR), Lam, TuKiet T.^4,5 (AUTHOR), Chandra, Sreeganga S.¹ (AUTHOR) sreeganga.chandra@yale.edu

Publikováno v: PLoS Biology. 3/31/2022, Vol. 20 Issue 3, p1-36. 36p. 1 Color Photograph, 3 Diagrams, 3 Charts, 1 Graph.

Recent insights into the networking of CLN genes and proteins in mammalian cells.

Autor: Huber, Robert J.

Publikováno v: Journal of Neurochemistry; Jun2023, Vol. 165 Issue 5, p643-659, 17p

Regulation of Death Receptor Signaling by S-Palmitoylation and Detergent-Resistant Membrane Micro Domains—Greasing the Gears of Extrinsic Cell Death Induction, Survival, and Inflammation.

Autor: Fritsch, Jürgen¹ (AUTHOR) Wulf.Schneider@ukr.de, Särchen, Vinzenz² (AUTHOR) v.saerchen@kinderkrebsstiftung-frankfurt.de, Schneider-Brachert, Wulf¹ (AUTHOR)

Publikováno v: Cancers. Jun2021, Vol. 13 Issue 11, p2513. 1p.

The Networks of Genes Encoding Palmitoylated Proteins in Axonal and Synaptic Compartments Are Affected in PPT1 Overexpressing Neuronal-Like Cells.

Autor: Pezzini, Francesco, Bianchi, Marzia, Benfatto, Salvatore, Griggio, Francesca, Doccini, Stefano, Carrozzo, Rosalba, Dapkunas, Arvydas, Delledonne, Massimo, Santorelli, Filippo M., Lalowski, Maciej M., Simonati, Alessandro

Publikováno v: Frontiers in Molecular Neuroscience; 8/22/2017, p1-18, 18p