Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Morakot Likhitpanichkul"'
Autor:
Benjamin A Walter, Morakot Likhitpanichkul, Svenja Illien-Junger, Peter J Roughley, Andrew C Hecht, James C Iatridis
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118358 (2015)
Intervertebral disc (IVD) degeneration is an important contributor to the development of back pain, and a key factor relating pain and degeneration are the presence of pro-inflammatory cytokines and IVD motion. There is surprisingly limited understan
Externí odkaz:
https://doaj.org/article/e84fc30f9a2f4ccbad50e894c1f7e35b
Autor:
Morakot Likhitpanichkul, James C. Iatridis, Jadry Gruen, Andrew C. Hecht, Olivia M. Torre, Benjamin A. Walter
Publikováno v:
Journal of Biomechanics. 49:1214-1220
During intervertebral disc (IVD) injury and degeneration, annulus fibrosus (AF) cells experience large mechanical strains in a pro-inflammatory milieu. We hypothesized that TNF-α, an initiator of IVD inflammation, modifies AF cell mechanobiology via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d35bf03d20860d637f372b3c2c637b
https://doi.org/10.1016/j.jbiomech.2016.02.029
https://doi.org/10.1016/j.jbiomech.2016.02.029
Autor:
James C. Iatridis, Morakot Likhitpanichkul, Steven B. Nicoll, Khyati Dave, Olivia M. Torre, Clare Canal Guterl, Devina Purmessur, Andrew C. Hecht
Publikováno v:
Tissue Engineering Part A. 20:2536-2545
There is an unmet clinical need for a biomaterial sealant capable of repairing small annulus fibrosus (AF) defects. Causes of these defects include painful intervertebral disc herniations, microdiscectomy procedures, morbidity associated with needle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52091512899cd0b7d6456ffbe819377
https://doi.org/10.1089/ten.tea.2012.0714
https://doi.org/10.1089/ten.tea.2012.0714
Publikováno v:
Biomaterials. 31:2489-2497
Cell-substrate interactions are multifaceted, involving the integration of various physical and biochemical signals. The interactions among these microenvironmental factors cannot be facilely elucidated and quantified by conventional experimentation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d63fee872f0b9eeab030cc7ef561967
https://doi.org/10.1016/j.biomaterials.2009.12.002
https://doi.org/10.1016/j.biomaterials.2009.12.002
Autor:
Samuel K. Cho, Morakot Likhitpanichkul, Devina Purmessur, Benjamin A. Walter, James C. Iatridis, Sheeraz A. Qureshi, Alan D. Weinberg, Andrew C. Hecht
Publikováno v:
Spine. 40(13)
Human nucleus pulposus (NP) cell culture study investigating response to tumor necrosis factor-α (TNFα), effectiveness of clinically available anti-inflammatory drugs, and interactions between proinflammatory cytokines.To characterize the kinetic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432ddde8a5646e5518f933bddeb72291
https://pubmed.ncbi.nlm.nih.gov/25893355
https://pubmed.ncbi.nlm.nih.gov/25893355
Autor:
Svenja Illien-Jünger, Benjamin A. Walter, Andrew C. Hecht, Morakot Likhitpanichkul, James C. Iatridis, Peter J. Roughley
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0118358 (2015)
PLoS ONE, Vol 10, Iss 3, p e0118358 (2015)
Objective Intervertebral disc (IVD) degeneration is an important contributor to the development of back pain, and a key factor relating pain and degeneration are the presence of pro-inflammatory cytokines and IVD motion. There is surprisingly limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48224e2fa1a6463e8d5c81a24bc99e9d
http://europepmc.org/articles/PMC4348425
http://europepmc.org/articles/PMC4348425
Publikováno v:
Journal of Biomechanics. 39:464-475
The theory of mixtures is applied to the analysis of the passive response of cells to osmotic loading with neutrally charged solutes. The formulation, which is derived for multiple solute species, incorporates partition coefficients for the solutes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454de05ea46f5c162c222ac9f04c97e0
https://doi.org/10.1016/j.jbiomech.2004.12.013
https://doi.org/10.1016/j.jbiomech.2004.12.013
Autor:
Eugene See, Yesul T. Kim, Morakot Likhitpanichkul, Abhay Pandit, James C. Iatridis, Andrew C. Hecht, Olivia M. Torre, Zepur Kazezian
Publikováno v:
The spine journal : official journal of the North American Spine Society. 15(9)
Background context Intervertebral discs (IVDs) are attractive targets for local drug delivery because they are avascular structures with limited transport. Painful IVDs are in a chronic inflammatory state. Although anti-inflammatories show poor perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf53a0fd25a306639a415b1eaaa417d0
https://pubmed.ncbi.nlm.nih.gov/25912501
https://pubmed.ncbi.nlm.nih.gov/25912501
Autor:
Svenja Illien-Jünger, Daisuke Sakai, James C. Iatridis, Benjamin A. Walter, Rose G. Long, Morakot Likhitpanichkul, M Dreischarf, Tadashi Nukaga, Andrew C. Hecht
Publikováno v:
Europe PubMed Central
European Cells & Materials, Vol 28, Pp 25-38 (2014)
European Cells & Materials, Vol 28, Pp 25-38 (2014)
Annulus fibrosus (AF) defects from annular tears, herniation, and discectomy procedures are associated with painful conditions and accelerated intervertebral disc (IVD) degeneration. Currently, no effective treatments exist to repair AF damage, resto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957492eca301f7648aab1b1e22d38da7
https://pubmed.ncbi.nlm.nih.gov/25036053
https://pubmed.ncbi.nlm.nih.gov/25036053
Autor:
Milica Radisic, Rohin K. Iyer, Wen Li Kelly Chen, Bashir Bhana, Ruogang Zhao, Krista L. Sider, Craig A. Simmons, Morakot Likhitpanichkul
Publikováno v:
Biotechnology and bioengineering. 105(6)
Adult cardiomyocytes (CM) retain little capacity to regenerate, which motivates efforts to engineer heart tissues that can emulate the functional and mechanical properties of native myocardium. Although the effects of matrix stiffness on individual C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde72d22fe59b860dbb5e23be7f135fe
https://pubmed.ncbi.nlm.nih.gov/20014437
https://pubmed.ncbi.nlm.nih.gov/20014437