Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Morag Ellison"'
Publikováno v:
JNCI: Journal of the National Cancer Institute. 59:309-312
Autor:
K. D. R. Setchell, R. L. Himsworth, J. J. H. Gilkes, P. J. Lowry, Glenys A. Bloomfield, G. Slavin, Lesley H. Rees, R. C. Coombes, Morag Ellison
Publikováno v:
Clinical Endocrinology. 7:45-62
A young man presented with rapidly developing Cushing's syndrome which was due to the ectopic secretion of ACTH and beta-MSH-like material from hepatic tumour deposits, possibly originating from biliary radicals. This association of the ectopic ACTH
Autor:
G. M. Rees, B. Corrin, J. G. Ratcliffe, I. M. Holdaway, Lesley H. Rees, Glenys A. Bloomfield, Morag Ellison
Publikováno v:
Clinical Endocrinology. 6:95-104
ACTH levels measured by N- and C-terminal immunoassays and cytochemical bioassay, were measured in fourteen lung tumours not associated with the ectopic ACTH syndrome and in macroscopically normal lung tissue taken from the same patients at thoracoto
Autor:
Morag Ellison
Publikováno v:
Proceedings of the Royal Society of Medicine. 70:845-850
Publikováno v:
International Journal of Cancer. 35:575-579
Eight out of 9 human squamous carcinoma cell lines ectopically secrete the beta subunit of human chorionic gonadotrophin (beta-HCG) in amounts detectable by radioimmunoassay. In contrast, both normal and SV40-transformed keratinocytes show no such ev
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 17:91-94
A method of estimating doses from multiple dilutions of an unknown sample in radioimmunoassay is described. It uses a computer program to minimise the root mean square error about a standard curve. The confidence limits of the estimates were evaluate
Autor:
Lesley H. Rees, Glenys A. Bloomfield, Morag Ellison, A. M. Neville, R. C. Coombes, Carmel J. Hillyard
Publikováno v:
Clinical Endocrinology. 5:s397-s406
SUMMARY Monolayer tissue culture has been used as a system in which to study aspects of ectopic hormone secretion. Of a series of twenty-four human bronchial carcinomas, nineteen were successfully established in culture and the supernatant medium fro
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 19:263-268
We have investigated the role of biochemical markers in breast and lung cancer but have found that currently available tests have little role in management. In breast cancer, for example, we have found that the most sensitive method for routine scree
Publikováno v:
Clinical endocrinology.
The possibility of a relationship between cyclic AMP formation and metabolic processes in tumours has been investigated. Changes in basal activity and hormone-responsiveness of adenylate cyclase were demonstrated in plasma membranes and intact cells
Publikováno v:
Biochemical pharmacology. 30(24)
Human bronchial carcinoma cell lines in monolayer cell culture were used to study the conjugation of 1-naphthol and 3-hydroxybenzo( a )pyrene, two phenolic substrates. Cell lines, able to metabolise 1-naphthol to glucuronic acid and sulphate ester co