Zobrazeno 1 - 10 of 782 pro vyhledávání: '"Moraca, F."'
1
Akademický článek
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis.
Autor: Rapacciuolo P; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Finamore C; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Giorgio CD; Department of Medicine and Surgery, University of Perugia, Piazza L. Severi, 1, Perugia 06132, Italy., Fiorillo B; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Massa C; Department of Medicine and Surgery, University of Perugia, Piazza L. Severi, 1, Perugia 06132, Italy., Urbani G; Department of Medicine and Surgery, University of Perugia, Piazza L. Severi, 1, Perugia 06132, Italy., Marchianò S; Department of Medicine and Surgery, University of Perugia, Piazza L. Severi, 1, Perugia 06132, Italy., Bordoni M; Department of Medicine and Surgery, University of Perugia, Piazza L. Severi, 1, Perugia 06132, Italy., Cassiano C; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Morretta E; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Spinelli L; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Lupia A; Department of Life and Environmental Sciences, University of Cagliari, Via Università, 40, Cagliari 09124, Italy., Moraca F; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Biagioli M; Department of Medicine and Surgery, University of Perugia, Piazza L. Severi, 1, Perugia 06132, Italy., Sepe V; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Monti MC; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Catalanotti B; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy., Fiorucci S; Department of Medicine and Surgery, University of Perugia, Piazza L. Severi, 1, Perugia 06132, Italy., Zampella A; Department of Pharmacy, University of Naples 'Federico II', Via D. Montesano, 49, Naples I-80131, Italy.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2024 Oct 24; Vol. 67 (20), pp. 18334-18355. Date of Electronic Publication: 2024 Oct 09.
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2
Author Correction: Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system.
Autor: Rinaldi L; Department of Molecular Medicine and Medical Biotechnologies, University Federico II, 80131, Naples, Italy., Donne RD; Department of Molecular Medicine and Medical Biotechnologies, University Federico II, 80131, Naples, Italy., Catalanotti B; Department of Pharmacy, University Federico II, 80131, Naples, Italy., Torres-Quesada O; Institute of Biochemistry and Center for Molecular Biosciences, University of Innsbruck, A-, 6020, Innsbruck, Austria., Enzler F; Institute of Biochemistry and Center for Molecular Biosciences, University of Innsbruck, A-, 6020, Innsbruck, Austria., Moraca F; Department of Chemical Sciences, University Federico II, 80131, Naples, Italy., Nisticò R; European Brain Research Institute, Rita Levi-Montalcini Foundation and Department of Biology, University Tor Vergata, 00143, Rome, Italy., Chiuso F; Department of Molecular Medicine and Medical Biotechnologies, University Federico II, 80131, Naples, Italy., Piccinin S; European Brain Research Institute, Rita Levi-Montalcini Foundation and Department of Biology, University Tor Vergata, 00143, Rome, Italy., Bachmann V; Institute of Biochemistry and Center for Molecular Biosciences, University of Innsbruck, A-, 6020, Innsbruck, Austria., Lindner HH; Division of Clinical Biochemistry, Biocenter Medical University of Innsbruck, Innrain 80-82, A-6020, Innsbruck, Austria., Garbi C; Department of Molecular Medicine and Medical Biotechnologies, University Federico II, 80131, Naples, Italy., Scorziello A; Department of Neuroscience, Reproductive and Odontostomatological Sciences, University Federico II, 80131, Naples, Italy., Russo NA; I.R.C.S., BIOGEM, Ariano Irpino, 83031, Avellino, Italy., Synofzik M; Department of Neurodegeneration, Hertie Institute for Clinical Brain Research (HIH), University of Tübingen and German Center for Neurodegenerative Diseases (DZNE), 72076, Tübingen, Germany., Stelzl U; Institute of Pharmaceutical Sciences, University of Graz and BioTechMed-Graz, 8010, Graz, Austria., Annunziato L; IRCCS SDN, 80143, Naples, Italy., Stefan E; Institute of Biochemistry and Center for Molecular Biosciences, University of Innsbruck, A-, 6020, Innsbruck, Austria., Feliciello A; Department of Molecular Medicine and Medical Biotechnologies, University Federico II, 80131, Naples, Italy. feliciel@unina.it.
Publikováno v: Nature communications [Nat Commun] 2024 May 29; Vol. 15 (1), pp. 4565. Date of Electronic Publication: 2024 May 29.
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3
Akademický článek
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis.
Autor: Di Giorgio C; University of Perugia, Department of Medicine and Surgery, Perugia, Italy., Morretta E; University of Salerno, Department of Pharmacy, Salerno, Italy., Lupia A; University of Cagliari, Department of Life and Environmental Sciences, Cagliari, Italy; Net4Science srl, University 'Magna Græcia', Campus Salvatore Venuta, Viale Europa, Catanzaro 88100, Italy., Bellini R; University of Perugia, Department of Medicine and Surgery, Perugia, Italy., Massa C; University of Perugia, Department of Medicine and Surgery, Perugia, Italy., Urbani G; University of Perugia, Department of Medicine and Surgery, Perugia, Italy., Bordoni M; University of Perugia, Department of Medicine and Surgery, Perugia, Italy., Marchianò S; University of Perugia, Department of Medicine and Surgery, Perugia, Italy., Lachi G; University of Perugia, Department of Medicine and Surgery, Perugia, Italy., Rapacciuolo P; University of Naples Federico II, Department of Pharmacy, Naples, Italy., Finamore C; University of Naples Federico II, Department of Pharmacy, Naples, Italy., Sepe V; University of Naples Federico II, Department of Pharmacy, Naples, Italy., Chiara Monti M; University of Salerno, Department of Pharmacy, Salerno, Italy., Moraca F; Net4Science srl, University 'Magna Græcia', Campus Salvatore Venuta, Viale Europa, Catanzaro 88100, Italy; University of Naples Federico II, Department of Pharmacy, Naples, Italy., Natalizi N; Azienda Ospedaliera di Perugia, Perugia, Italy., Graziosi L; Azienda Ospedaliera di Perugia, Perugia, Italy., Distrutti E; Azienda Ospedaliera di Perugia, Perugia, Italy., Biagioli M; University of Perugia, Department of Medicine and Surgery, Perugia, Italy., Catalanotti B; University of Naples Federico II, Department of Pharmacy, Naples, Italy., Donini A; University of Perugia, Department of Medicine and Surgery, Perugia, Italy., Zampella A; University of Naples Federico II, Department of Pharmacy, Naples, Italy., Fiorucci S; University of Perugia, Department of Medicine and Surgery, Perugia, Italy. Electronic address: stefano.fiorucci@unipg.it.
Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2024 May; Vol. 223, pp. 116134. Date of Electronic Publication: 2024 Mar 15.
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4
Akademický článek
Synthesis, biological evaluation and metadynamics simulations of novel N -methyl β-sheet breaker peptides as inhibitors of Alzheimer's β-amyloid fibrillogenesis.
Autor: Moraca F; Department of Pharmacy, University of Napoli Federico II Via Domenico Montesano 49 I-80131 Napoli Italy.; Net4Science Academic Spin-Off, University 'Magna Græcia' of Catanzaro Viale Europa 88100 Catanzaro Italy., Vespoli I; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences Flemingovo náměstí 542/2 CZ-16610 Prague Czech Republic., Mastroianni D; Department of Chemical Sciences, University of Napoli Federico II Via Cintia 4 I-80126 Napoli Italy., Piscopo V; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli' Viale Abramo Lincoln 5 I-81100 Caserta Italy., Gaglione R; Department of Chemical Sciences, University of Napoli Federico II Via Cintia 4 I-80126 Napoli Italy.; Istituto Nazionale di Biostrutture e Biosistemi (INBB) Viale delle Medaglie d'Oro 305 I-80145 Roma Italy., Arciello A; Department of Chemical Sciences, University of Napoli Federico II Via Cintia 4 I-80126 Napoli Italy.; Istituto Nazionale di Biostrutture e Biosistemi (INBB) Viale delle Medaglie d'Oro 305 I-80145 Roma Italy., De Nisco M; Department of Sciences, University of Basilicata Viale dell'Ateneo Lucano I-85100 Potenza Italy mauro.denisco@unibas.it., Pacifico S; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli' Viale Abramo Lincoln 5 I-81100 Caserta Italy., Catalanotti B; Department of Pharmacy, University of Napoli Federico II Via Domenico Montesano 49 I-80131 Napoli Italy., Pedatella S; Department of Chemical Sciences, University of Napoli Federico II Via Cintia 4 I-80126 Napoli Italy.
Publikováno v: RSC medicinal chemistry [RSC Med Chem] 2024 Apr 11; Vol. 15 (7), pp. 2286-2299. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).
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5
Akademický článek
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer.
Autor: Di Giorgio C; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Bellini R; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Lupia A; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.; Net4Science Srl, University 'Magna Græcia', Campus Salvatore Venuta, Viale Europa, 88100, Catanzaro, Italy., Massa C; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Urbani G; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Bordoni M; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Marchianò S; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Rosselli R; Department of Pharmacy, University of Naples Federico II, Naples, Italy., De Gregorio R; Department of Pharmacy, University of Naples Federico II, Naples, Italy., Rapacciuolo P; Department of Pharmacy, University of Naples Federico II, Naples, Italy., Sepe V; Department of Pharmacy, University of Naples Federico II, Naples, Italy., Morretta E; Department of Pharmacy, University of Salerno, Salerno, Italy., Monti MC; Department of Pharmacy, University of Salerno, Salerno, Italy., Moraca F; Net4Science Srl, University 'Magna Græcia', Campus Salvatore Venuta, Viale Europa, 88100, Catanzaro, Italy.; Department of Pharmacy, University of Naples Federico II, Naples, Italy., Cari L; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Ullah KRS; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Natalizi N; Azienda Ospedaliera Di Perugia, Perugia, Italy., Graziosi L; Azienda Ospedaliera Di Perugia, Perugia, Italy., Distrutti E; Azienda Ospedaliera Di Perugia, Perugia, Italy., Biagioli M; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Catalanotti B; Department of Pharmacy, University of Naples Federico II, Naples, Italy., Donini A; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Zampella A; Department of Pharmacy, University of Naples Federico II, Naples, Italy., Fiorucci S; Department of Medicine and Surgery, University of Perugia, Perugia, Italy. stefano.fiorucci@unipg.it.; Department Surgical and Biomedical Sciences, University of Perugia Medical School, Perugia, Italy. stefano.fiorucci@unipg.it.
Publikováno v: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2024 Apr; Vol. 47 (2), pp. 695-710. Date of Electronic Publication: 2023 Nov 09.
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6
Akademický článek
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7
Akademický článek
Exploring the DNA 2 -PNA heterotriplex formation in targeting the Bcl-2 gene promoter: A structural insight by physico-chemical and microsecond-scale MD investigation.
Autor: Falanga AP; Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy., Lupia A; Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy., Tripodi L; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy.; CEINGE-Biotecnologie Avanzate Franco Salvatore S.c.a.r.l., Naples, 80145, Italy., Morgillo CM; Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy., Moraca F; Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy., Roviello GN; Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche, Naples, 80131, Italy., Catalanotti B; Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy., Amato J; Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy., Pastore L; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy.; CEINGE-Biotecnologie Avanzate Franco Salvatore S.c.a.r.l., Naples, 80145, Italy., Cerullo V; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy.; ImmunoViroTherapy Lab (IVT), Drug Research Program (DRP), Faculty of Pharmacy, University of Helsinki, 00100, Helsinki, Finland., D'Errico S; Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy., Piccialli G; Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy., Oliviero G; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy., Borbone N; Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, Naples, 80131, Italy.
Publikováno v: Heliyon [Heliyon] 2024 Jan 22; Vol. 10 (3), pp. e24599. Date of Electronic Publication: 2024 Jan 22 (Print Publication: 2024).
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In Vitro and in Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas
Autor: Singh, A., Ling, Y., Vendome, J., Sacchettini, J.C., Roubert, C., Perkowski, A.J., Aubé, J., Roberts, J., Gold, B.S., Lagiakos, H.R., Moraca, F., Tracy, W., Bowler, M.M., Bacqué, E., Ramesh, R., Goullieux, L., Ottavi, S., Nathan, C.F., Li, K., Scarry, S.M., Zhang, D., Feher, V.A., Mosior, J.
A newly validated target for tuberculosis treatment is phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. The structure-activity
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9cca19e053457fe804eac1697cfa3684
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9
Akademický článek
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients.
Autor: Gratteri C; Dipartimento di Scienze della Salute, Campus 'S. Venuta', Università degli Studi 'Magna Græcia' di Catanzaro, Viale Europa, 88100 Catanzaro, Italy., Ambrosio FA; Dipartimento di Medicina Sperimentale e Clinica, Campus 'S. Venuta', Università degli Studi 'Magna Græcia' di Catanzaro, Viale Europa, 88100 Catanzaro, Italy., Lupia A; Dipartimento di Scienze della vita e dell'ambiente, Università degli Studi di Cagliari, Cittadella Universitaria di Monserrato, 09124 Cagliari, Italy.; Net4Science S.r.l., Università degli Studi 'Magna Græcia' di Catanzaro, 88100 Catanzaro, Italy., Moraca F; Net4Science S.r.l., Università degli Studi 'Magna Græcia' di Catanzaro, 88100 Catanzaro, Italy.; Dipartimento di Farmacia, Università degli Studi di Napoli 'Federico II', Via D. Montesano 49, 80131 Napoli, Italy., Catalanotti B; Dipartimento di Farmacia, Università degli Studi di Napoli 'Federico II', Via D. Montesano 49, 80131 Napoli, Italy., Costa G; Dipartimento di Scienze della Salute, Campus 'S. Venuta', Università degli Studi 'Magna Græcia' di Catanzaro, Viale Europa, 88100 Catanzaro, Italy.; Net4Science S.r.l., Università degli Studi 'Magna Græcia' di Catanzaro, 88100 Catanzaro, Italy., Bellocchi M; Dipartimento di Medicina Sperimentale, Università Tor Vergata di Roma, Via Montpellier, 1, 00133 Roma, Italy., Carioti L; Dipartimento di Medicina Sperimentale, Università Tor Vergata di Roma, Via Montpellier, 1, 00133 Roma, Italy., Salpini R; Dipartimento di Medicina Sperimentale, Università Tor Vergata di Roma, Via Montpellier, 1, 00133 Roma, Italy., Ceccherini-Silberstein F; Dipartimento di Medicina Sperimentale, Università Tor Vergata di Roma, Via Montpellier, 1, 00133 Roma, Italy., Frazia S; Dipartimento di Biologia, Università Tor Vergata di Roma, Via della Ricerca Scientifica, 1, 00133 Roma, Italy., Malagnino V; Dipartimento di Medicina dei Sistemi, Università Tor Vergata di Roma, Via Montpellier, 1, 00133 Roma, Italy., Sarmati L; Dipartimento di Medicina dei Sistemi, Università Tor Vergata di Roma, Via Montpellier, 1, 00133 Roma, Italy., Svicher V; Dipartimento di Biologia, Università Tor Vergata di Roma, Via della Ricerca Scientifica, 1, 00133 Roma, Italy., Bryant S; Inte:Ligand GmbH, Mariahilferstrasse 74B/11, 1070 Vienna, Austria., Artese A; Dipartimento di Scienze della Salute, Campus 'S. Venuta', Università degli Studi 'Magna Græcia' di Catanzaro, Viale Europa, 88100 Catanzaro, Italy.; Net4Science S.r.l., Università degli Studi 'Magna Græcia' di Catanzaro, 88100 Catanzaro, Italy., Alcaro S; Dipartimento di Scienze della Salute, Campus 'S. Venuta', Università degli Studi 'Magna Græcia' di Catanzaro, Viale Europa, 88100 Catanzaro, Italy.; Net4Science S.r.l., Università degli Studi 'Magna Græcia' di Catanzaro, 88100 Catanzaro, Italy.
Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Aug 12; Vol. 16 (8). Date of Electronic Publication: 2023 Aug 12.
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10
Akademický článek
Ubiquitylation of BBSome is required for ciliary assembly and signaling.
Autor: Chiuso F; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', Naples, Italy., Delle Donne R; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', Naples, Italy., Giamundo G; Telethon Institute of Genetics and Medicine, Pozzuoli, Italy.; Department of Biology, University of Naples Federico II, Naples, Italy., Rinaldi L; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', Naples, Italy., Borzacchiello D; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', Naples, Italy., Moraca F; Department of Pharmacy, University of Naples 'Federico II', Naples, Italy.; Net4Science srl, University 'Magna Graecia' of Catanzaro, Catanzaro, Italy., Intartaglia D; Telethon Institute of Genetics and Medicine, Pozzuoli, Italy., Iannucci R; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', Naples, Italy., Senatore E; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', Naples, Italy., Lignitto L; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', Naples, Italy.; Cancer Research Center of Marseille (CRCM), CNRS, Aix Marseille Univ, INSERM, Institut Paoli-Calmettes, Marseille, France., Garbi C; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', Naples, Italy., Conflitti P; Faculty of Biomedical Sciences, Institute of Computational Science, Università della Svizzera Italiana (USI), Lugano, Switzerland., Catalanotti B; Department of Pharmacy, University of Naples 'Federico II', Naples, Italy., Conte I; Telethon Institute of Genetics and Medicine, Pozzuoli, Italy.; Department of Biology, University of Naples Federico II, Naples, Italy., Feliciello A; Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II', Naples, Italy.
Publikováno v: EMBO reports [EMBO Rep] 2023 Apr 05; Vol. 24 (4), pp. e55571. Date of Electronic Publication: 2023 Feb 06.
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