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Akademický článek

KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells

Autor: Woessner Richard, Tytler Ewan M, Xie Yanhua, Kim Ki, Mor Gil, Alvero Ayesha B

Publikováno v: Journal of Translational Medicine, Vol 7, Iss 1, p 63 (2009)

Abstract Background We previously described a sub-population of epithelial ovarian cancer (EOC) cells with a functional TLR-4/MyD88/NF-κB pathway (Type I EOC cells), which confers the capacity to respond to Paclitaxel, a known TLR-4 ligand, by enhan

Externí odkaz: https://doaj.org/article/edfad35e31cd49838d642514b8067266

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Akademický článek

The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization

Autor: Camp Robert L, Ariyan Stephan, Sznol Mario, Alvero Ayesha B, McCarthy Mary M, Kluger Harriet M, Rimm David L, Mor Gil

Publikováno v: Journal of Translational Medicine, Vol 5, Iss 1, p 6 (2007)

Abstract XIAP up-regulation is associated with chemotherapy resistance. Phenoxodiol causes XIAP degradation and chemotherapy sensitization in ovarian cancer. Here we assessed XIAP expression in melanomas, using tissue microarrays containing 436 melan

Externí odkaz: https://doaj.org/article/c21ac9eeea434a6ab3c9dce6282b9c4a

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Akademický článek

Potential role of macrophages as immunoregulators of pregnancy

Autor: Abrahams Vikki M, Mor Gil

Publikováno v: Reproductive Biology and Endocrinology, Vol 1, Iss 1, p 119 (2003)

Abstract The role of the maternal immune system during pregnancy has focused mainly on the aspect of immune tolerance to the invading trophoblast and, therefore, fetus. While this is a critical aspect of reproductive immunology, it is also important

Externí odkaz: https://doaj.org/article/c7d7a4f004b2474890c854c6cebd2ca8

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