Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways.

Autor: Gutierrez DA; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Contreras L; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Villanueva PJ; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Borrego EA; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Morán-Santibañez K; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Hess JD; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., DeJesus R; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Larragoity M; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Betancourt AP; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Mohl JE; Department of Bioinformatics, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Robles-Escajeda E; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Begum K; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Roy S; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Kirken RA; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Varela-Ramirez A; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA., Aguilera RJ; Cellular Characterization and Biorepository Core Facility, Border Biomedical Research Center, Department of Biological Sciences, College of Science, The University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968-0519, USA.

Publikováno v: Cells [Cells] 2022 Jan 12; Vol. 11 (2). Date of Electronic Publication: 2022 Jan 12.

A Novel Pyrazole Exhibits Potent Anticancer Cytotoxicity via Apoptosis, Cell Cycle Arrest, and the Inhibition of Tubulin Polymerization in Triple-Negative Breast Cancer Cells.

Autor: Borrego, Edgar A.^1,2 (AUTHOR) c.guerena7@gmail.com, Guerena, Cristina D.^1,2 (AUTHOR) aschiaf@emory.edu, Schiaffino Bustamante, Austre Y.^1,2 (AUTHOR) dagutierrez5@utep.edu, Gutierrez, Denisse A.^1,2 (AUTHOR) car_los_alejandro@hotmail.com, Valenzuela, Carlos A.^1,2 (AUTHOR) abetancourt@utep.edu, Betancourt, Ana P.^1,2 (AUTHOR) avarela2@utep.edu, Varela-Ramirez, Armando^1,2 (AUTHOR), Aguilera, Renato J.^1,2 (AUTHOR) eaborregopu@miners.utep.edu

Publikováno v: Cells (2073-4409). Jul2024, Vol. 13 Issue 14, p1225. 19p.

Virucidal Activity of Gold Nanoparticles Synthesized by Green Chemistry Using Garlic Extract.

Autor: Meléndez-Villanueva MA; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Ciudad Universitaria, CP 66455 San Nicolás de los Garza, Mexico., Morán-Santibañez K; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Ciudad Universitaria, CP 66455 San Nicolás de los Garza, Mexico., Martínez-Sanmiguel JJ; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Ciudad Universitaria, CP 66455 San Nicolás de los Garza, Mexico., Rangel-López R; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Ciudad Universitaria, CP 66455 San Nicolás de los Garza, Mexico., Garza-Navarro MA; Facultad de Ingeniería Mecánica y Eléctrica, Universidad Autónoma de Nuevo León, Ciudad Universitaria, CP 66455 San Nicolás de los Garza, Mexico., Rodríguez-Padilla C; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Ciudad Universitaria, CP 66455 San Nicolás de los Garza, Mexico., Zarate-Triviño DG; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Ciudad Universitaria, CP 66455 San Nicolás de los Garza, Mexico., Trejo-Ávila LM; Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Ciudad Universitaria, CP 66455 San Nicolás de los Garza, Mexico.

Publikováno v: Viruses [Viruses] 2019 Nov 30; Vol. 11 (12). Date of Electronic Publication: 2019 Nov 30.

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Assessing the Antioxidant Properties of Larrea tridentata Extract as a Potential Molecular Therapy against Oxidative Stress.

Autor: Skouta R; Department of Biology, University of Massachusetts, Amherst, MA 01003-9297, USA. rskouta@umass.edu.; Department of Chemistry and Biochemistry, Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA. rskouta@umass.edu., Morán-Santibañez K; Department of Chemistry and Biochemistry, Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA. ksmoransant@utep.edu., Valenzuela CA; Department of Biology, Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA. cavalenzuela4@miners.utep.edu., Vasquez AH; Department of Chemistry and Biochemistry, Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA. ahvasquez@miners.utep.edu., Fenelon K; Department of Biology, University of Massachusetts, Amherst, MA 01003-9297, USA. kfenelon@umass.edu.; Department of Biology, Border Biomedical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA. kfenelon@umass.edu.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2018 Jul 23; Vol. 23 (7). Date of Electronic Publication: 2018 Jul 23.