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Akademický článek

Alteration of Gut Microbiome and Correlated Amino Acid Metabolism Contribute to Hyperuricemia and Th17-Driven Inflammation in Uox-KO Mice

Autor: Siyue Song, Yu Lou, Yingying Mao, Xianghui Wen, Moqi Fan, Zhixing He, Yang Shen, Chengping Wen, Tiejuan Shao

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Although gut dysbiosis had been demonstrated to be an important factor affecting hyperuricemia (HUA) and gout, little is known for its potential mechanistic connections. In this study, Uox-KO mice model that with spontaneously developed pronounced HU

Externí odkaz: https://doaj.org/article/bc55fa2b7ddf4979b904005fe3fd18eb

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Integrated Network Pharmacology and Gut Microbiome Analysis to Reveal the Mechanism of Qu-Zhuo-Tong-Bi Decoction Against Hyperuricemia and Gout

Autor: Siyue Song, Moqi Fan, Xianghui Wen, Xiaowei Shi, Yu Lou, Zhixing He, Chengping Wen, Tiejuan Shao

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c4cf1b8cc4c9cc0ad8159d40ae2b1d2
https://doi.org/10.2139/ssrn.4356747

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Identification of absorbed constituents and evaluation of the pharmacokinetics of main compounds after oral administration of yindanxinnaotong by UPLC-Q-TOF-MS and UPLC-QqQ-MS

Autor: Huijun Yuan, Leilei Gong, Xu Haiyu, Hongjun Yang, Liang Rixin, Long Cheng, Xiaojing Ma, Lan Wang, Moqi Fan, Xiaojie Yin

Publikováno v: RSC Advances. 8:15725-15739

Yindanxinnaotong capsule (YDXNT), a traditional Chinese formula, has been used to treat cardio-cerebrovascular diseases for several decades. Previous research has focused on evaluating the pharmacological properties and main compounds of YDXNT in vit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::947534de06901da052ed2856634db086
https://doi.org/10.1039/c7ra12659j

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