A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys.

Autor: Douglas AD; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK. Electronic address: sandy.douglas@ndm.ox.ac.uk., Baldeviano GC; US Naval Medical Research Unit No. 6 (NAMRU-6), Lima, Peru., Lucas CM; US Naval Medical Research Unit No. 6 (NAMRU-6), Lima, Peru., Lugo-Roman LA; US Naval Medical Research Unit No. 6 (NAMRU-6), Lima, Peru., Crosnier C; Wellcome Trust Sanger Institute, Cambridge CB10 1HH, UK., Bartholdson SJ; Wellcome Trust Sanger Institute, Cambridge CB10 1HH, UK., Diouf A; Laboratory of Malaria and Vector Research, NIAID/NIH, Rockville, MD 20852, USA., Miura K; Laboratory of Malaria and Vector Research, NIAID/NIH, Rockville, MD 20852, USA., Lambert LE; Laboratory of Malaria Immunology and Vaccinology, NIAID/NIH, Rockville, MD 20852, USA., Ventocilla JA; US Naval Medical Research Unit No. 6 (NAMRU-6), Lima, Peru., Leiva KP; US Naval Medical Research Unit No. 6 (NAMRU-6), Lima, Peru., Milne KH; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Illingworth JJ; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Spencer AJ; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Hjerrild KA; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Alanine DG; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Turner AV; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK., Moorhead JT; US Naval Medical Research Unit No. 6 (NAMRU-6), Lima, Peru., Edgel KA; US Naval Medical Research Unit No. 6 (NAMRU-6), Lima, Peru., Wu Y; Laboratory of Malaria Immunology and Vaccinology, NIAID/NIH, Rockville, MD 20852, USA., Long CA; Laboratory of Malaria and Vector Research, NIAID/NIH, Rockville, MD 20852, USA., Wright GJ; Wellcome Trust Sanger Institute, Cambridge CB10 1HH, UK., Lescano AG; US Naval Medical Research Unit No. 6 (NAMRU-6), Lima, Peru., Draper SJ; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.

Publikováno v: Cell host & microbe [Cell Host Microbe] 2015 Jan 14; Vol. 17 (1), pp. 130-9.